Publication: Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes
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Date
2014-04-01T00:00:00Z
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Yeo, Adeline S. L.
Azhar, Nur Atiqah
Yeow, Wanyi
Talbot, C. Conover
Khan, MOHAMMAD ASİF
Shankar, Esaki M.
Rathakrishnan, Anusyah
Azizan, Azliyati
Wang, Seok Mui
Lee, Siew Kim
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Abstract
Objectives: Dengue represents one of the most serious life-threatening vector-borne infectious diseases that afflicts approximately 50 million people across the globe annually. Whilst symptomatic infections are frequently reported, asymptomatic dengue remains largely unnoticed. Therefore, we sought to investigate the immune correlates conferring protection to individuals that remain clinically asymptomatic.
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Yeo A. S. L. , Azhar N. A. , Yeow W., Talbot C. C. , Khan M. A. , Shankar E. M. , Rathakrishnan A., Azizan A., Wang S. M. , Lee S. K. , et al., -Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes-, PLOS ONE, cilt.9, sa.4, 2014