Publication: Role of cathepsin D activation in major adverse cardiovascular events and new-onset heart failure after STEMI
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Date
2015-04-01
Authors
ERCAN, ÇİLEM
YAMAÇ, AYLİN HATİCE
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Abstract
Increased serum levels of the activated aspartic lysosomal endopeptidase cathepsin D (CatD) have been found in patients with acute myocardial infarction (AMI). However, to date there have been no analyses of clinical follow-up data measuring the enzyme course and its role in the development of post-MI heart failure. This study aimed to evaluate the role of serum CatD activity in the development of heart failure in patients with ST-segment elevation acute myocardial infarction (STEMI).
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YAMAÇ A. H. , ERCAN Ç., -Role of cathepsin D activation in major adverse cardiovascular events and new-onset heart failure after STEMI-, HERZ, no.6, ss.912-920, 2015