Publication:
Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease

No Thumbnail Available
Date
2018-01-01T00:00:00Z
Authors
Acikgoz, NUSRET
Kurtoglu, Ertugrul
Yagmur, Julide
KAPICIOĞLU, YELDA
CANSEL, MEHMET
ERMİŞ, NECİP
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue

Metrics

Search on Google Scholar

Abstract
Behcet disease (BD) is a multisystemic disorder characterized by endothelial dysfunction and inflammation. Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress. Sixty patients with BD and 50 control individuals were included to investigate the relationship between MHR and endothelial dysfunction. Endothelial function was assessed by flow- and nitroglycerin-mediated dilatation technique (FMD and NMD, respectively). Serum high-sensitivity C-reactive protein (hsCRP) levels were measured in all study participants. The MHR and hsCRP levels were significantly higher in patients with active BD than in controls. Brachial artery FMD was significantly lower in patients with active BD than in controls. Brachial artery NMD was similar between groups. There was a strong inverse correlation between MHR and FMD and a strong positive correlation between MHR and serum hsCRP levels. Thus, elevated MHR may be a useful marker reflecting impaired endothelial function and systemic inflammation in patients with BD.
Description
Keywords
Citation
Acikgoz N., Kurtoglu E., Yagmur J., KAPICIOĞLU Y., CANSEL M., ERMİŞ N., -Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease-, ANGIOLOGY, cilt.69, ss.65-70, 2018
Collections
Page Views

0

File Downloads

0

Sustainable Development Goals