Search
Now showing items 1-10 of 108
Chemopreventive efficacy of stampidine in a murine breast cancer model
(2020-02-07)
Background: The purpose of the present study was to examine the chemopreventive effect of stampidine, an aryl phosphate derivative of stavudine, in side by side comparison with the standard anti-breast cancer drug paclitaxel ...
Chronotype and Sleep Quality in Patients with Inflammatory Bowel Disease
(2020-01-01)
Aim: Chronotype and sleep disturbance are both considered risk factors for chronic autoimmune diseases. However, there is lack of knowledge with respect to chronic inflammatory bowel disease and chronotype patterns. ...
Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium <i>Vibrio cholerae</i>.
(2020-04-29)
Due to the increasing resistance of currently used antimicrobial drugs, there is an
urgent problem for the treatment of cholera disease, selective inhibition of the α-class carbonic
anhydrases (CA, EC 4.2.1.1) from the ...
Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors.
(2020-04-22)
In our efforts to find new and selective thiazolidinone-based anti-Candida agents,
we synthesized and tested 26 thiazolidinones against several Candida spp. and Gram-positive
and Gram-negative bacteria. The compounds ...
Development of a framework for minimum and optimal safety and quality standards for hemodialysis and peritoneal dialysis
(2020-03-01)
Substantial heterogeneity in practice patterns around the world has resulted in wide variations in the quality and type of dialysis care delivered. This is particularly so in countries without universal standards of care ...
Capturing and monitoring global differences in untreated and treated end-stage kidney disease, kidney replacement therapy modality, and outcomes
(2020-03-01)
A large gap between the number of people with end-stage kidney disease (ESKD) who received kidney replacement therapy (KRT) and those who needed it has been recently identified, and it is estimated that approximately ...
Simulation of three intraoral radiographic techniques in pediatric dental patients: subjective comfort assessment using the VAS and Wong-Baker FACES Pain Raiting Scale
(2020-01-01)
Background Perception of pain associated with intraoral radiography in pediatric patients was evaluated through statistical comparisons of data obtained using the Wong-Baker FACES Pain Raiting Scale (WBFPRS) and visual ...
Triterpenoids and steroids isolated from Anatolian Capparis ovata and their activity on the expression of inflammatory cytokines
(2020-01-01)
Context: Capparis L. (Capparaceae) is grown worldwide. Caper has been used in traditional medicine to
treat various diseases including rheumatism, kidney, liver, stomach, as well as headache and toothache.
Objective: To ...