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dc.contributor.authorHamurcu, Mualla
dc.contributor.authorEKİNCİ, CANSU
dc.contributor.authorKoca, Semra
dc.contributor.authorTUĞCU, Betül
dc.date.accessioned2021-01-19T20:59:51Z
dc.date.available2021-01-19T20:59:51Z
dc.date.issued2021-01-01T00:00:00Z
dc.identifier.citationHamurcu M., EKİNCİ C., Koca S., TUĞCU B., -Evaluation of amblyopic eyes with optical coherence tomography angiography and electrophysiological tests-, INDIAN JOURNAL OF OPHTHALMOLOGY, cilt.69, ss.105-110, 2021
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28009
dc.description.abstractPurpose: To investigate the structural and functional changes of the retina and optic nerve in amblyopia. Methods: Eighteen patients with unilateral anisometropic amblyopia and 27 age-matched healthy controls were involved in this study. All patients underwent optical coherence tomography angiography (OCTA), pattern visual evoked potential (pVEP), and flash electroretinogram (fERG). Results: There was no statistically significant difference in terms of the fovea] avascular zone (FAZ), perifoveal superficial density, whole superficial density, parafoveal deep density, perifoveal deep density among the eyes (P > 0 0.05). Significant differences were found only in superficial capillary plexus (SCP) vessel density in whole (P = 0.029) and parafoveal (P = 0.008) image. In electrophysiological tests, while VEP latencies of the amblyopic eyes increased compared to nonamblyopic eyes and controls (P = 0.027), VEP amplitudes decreased in amblyopic and nonamblyopic eyes compared to controls (P = 0.01), amplitudes of the rod (P = 0.027) and cones (P < 0.001) also decreased in amblyopic eyes compared to nonamblyopic and healthy eyes. When we assessed the correlation between the parameters of OCTA and electrophysiological test, only a significant correlation was found between parafoveal SCP vessel density and VEP amplitudes (r = 0.341). Conclusion: We found a significant decrease only in SCP vessel density of the OCTA parameters in amblyopic eyes compared to healthy eyes. We detected a significant relationship between parafoveal SCP vessel density and VEP parameters, which might be associated with the underlying pathophysiology of the amblyopia.
dc.subjectAmblyopia
dc.subjectelectroretinography
dc.subjectoptical coherence tomographic angiography
dc.subjectretina
dc.subjectvisual evoked potential
dc.titleEvaluation of amblyopic eyes with optical coherence tomography angiography and electrophysiological tests
dc.typeArticle
dc.identifier.wosWOS:000601311400030
dc.identifier.scopus85098147181
dc.identifier.doi10.4103/ijo.ijo_2319_19
dc.identifier.pubmed33323589
local.publication.isinternational1
dc.contributor.institutionauthorTUĞCU, Betül


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