Publication: Validation of microsatellite instability histology scores with Bethesda guidelines in hereditary nonpolyposis colorectal cancer
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Date
2017-04-01T00:00:00Z
Authors
Authors
Kaya, Mustafa
Basak, Fatih
Sisik, Abdullah
Hasbahceci, Mustafa
Bas, Gurhan
Alimoglu, Orhan
Topal, Cumhur Selcuk
Kir, Gozde
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Abstract
Aims: Hereditary nonpolyposis colorectal cancer (HNPCC) is a subgroup of colorectal cancer (CRC) which should be differentiated because of the high risk for additional cancers and risk evaluation for other family members, especially for CRC. It is not practical to perform genetic testing for all CRC patients; therefore, various prediction modalities, for example, Bethesda guideline (BG) were studied in the literature. We aimed to assess the association of microsatellite instability (MSI), histology scores, and BG for predicting HNPCC risk.
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Kaya M., Basak F., Sisik A., Hasbahceci M., Bas G., Alimoglu O., Topal C. S. , Kir G., -Validation of microsatellite instability histology scores with Bethesda guidelines in hereditary nonpolyposis colorectal cancer-, JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, cilt.13, ss.356-361, 2017