Publication: Neural precursor cell-expressed developmentally down-regulated 4-like: a new biomarker in the pathophysiology of endometrial cancer
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Date
2018-09-01T00:00:00Z
Authors
Authors
YILMAZ, ERCAN
GÜL, MEHMET
MELEKOĞLU, RAUF
Coskun, Ebru Inci
Sahin, NURHAN
GÜL, SEMİR
BAŞTEMUR, AYŞE GÜLÇİN
Ciplak, Baris
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Abstract
Objectives Endometrial cancer is the most frequent tumor of the female genital tract. Ubiquitin is a small protein (8.5 kDa) found in all eukaryotic cells, binds to substrate proteins via a three-phase enzymatic pathway referred to as ubiquitination and plays an important role in cellular stability. Neural precursor cell-expressed developmentally down-regulated 4-like (NEDD4L) functions in the last phase of this enzymatic process. In this study, we investigated NEDD4L protein expression in endometrial cancer.
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YILMAZ E., GÜL M., MELEKOĞLU R., Coskun E. I. , Sahin N., GÜL S., BAŞTEMUR A. G. , Ciplak B., -Neural precursor cell-expressed developmentally down-regulated 4-like: a new biomarker in the pathophysiology of endometrial cancer-, JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, cilt.46, ss.3709-3716, 2018