Publication: Olanzapine Intoxication-Related Transient Diabetes Insipidus
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Date
2011-01-01T00:00:00Z
Authors
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Kocer, Emel
ALÇELİK, AYTEKİN
CANAN, FATİH
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Abstract
Olanzapine is a second-generation atypical antipsychotic agent approved for the treatment of psychotic disorders and mania. The effects of olanzapine intoxication include central nervous system depression, hyperthermia, myosis, tachycardia, and orthostatic hypotension. Heretofore, only one case has been reported to develop polyuria after olanzapine overdose (560 mg). We describe a case that developed diabetes insipidus following massive olanzapine ingestion and returned to normal after desmopressin treatment.
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Kocer E., ALÇELİK A., CANAN F., -Olanzapine Intoxication-Related Transient Diabetes Insipidus-, RENAL FAILURE, cilt.33, ss.842-843, 2011