Publication:
A New Parameter Predicting Chronic Total Occlusion of Coronary Arteries: Platelet Distribution Width

No Thumbnail Available
Date
2014-01-01T00:00:00Z
Authors
Vatankulu, Mehmet Akif
Sonmez, Osman
Ertas, Gokhan
BACAKSIZ, AHMET
Turfan, Murat
Erdogan, Ercan
Tasal, Abdurrahman
Kul, Seref
Uyarel, Huseyin
Goktekin, Omer
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue
Abstract
Platelet distribution width (PDW) measures the variability in platelet size and is a marker of platelet activation. We investigated whether PDW is associated with the extent of coronary artery disease (CAD) and coronary total occlusions (CTOs). We studied 162 patients: 108 had a coronary lesion with a diameter stenosis of 50%, the CAD(+) group, and 54 patients had normal coronary anatomy, the CAD(-) group. The CAD(+) group was subdivided into CAD(+) CTO(+) and CAD(+) CTO(-) groups. Among patients with CAD, the CTO(+) group had a significantly greater PDW (%) than the CTO(-) group (16.9 +/- 2.8, 15.4 +/- 3.0, and 15.4 +/- 1.9, respectively; P = .008). In a receiver-operating characteristic analysis, a PDW cut point of 15.7% was identified in patients with CTO(+) (area under curve = 0.64, 95% confidence interval 0.54-0.75). A PDW value of more than 15.7% demonstrated a sensitivity of 64% and a specificity of 66%. The PDW is a simple platelet index that may predict the presence of CTO.
Description
Keywords
Citation
Vatankulu M. A. , Sonmez O., Ertas G., BACAKSIZ A., Turfan M., Erdogan E., Tasal A., Kul S., Uyarel H., Goktekin O., -A New Parameter Predicting Chronic Total Occlusion of Coronary Arteries: Platelet Distribution Width-, ANGIOLOGY, cilt.65, ss.60-64, 2014
Sustainable Development Goals