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Gold nanoconjugates reinforce the potency of conjugated cisplatin and doxorubicin
Osteosarcoma or osteogenic sarcoma is the most common and prevalent cancerous tumor of bone and occurs especially in children and teens. Recent treatment strategy includes a combination of both chemotherapy and surgeries. ...
Glycyrrhizin induces reactive oxygen species-dependent apoptosis and cell cycle arrest at G(0)/G(1) in HPV18(+) human cervical cancer HeLa cell line
Cervical cancer is the fourth most common cancer among women worldwide and is a major cause of morbidity and mortality. High-risk Human Papilloma Virus (mostly type 16 & 18) infection is the primary risk factor for the ...
Prediction of functionally significant single nucleotide polymorphisms in PTEN tumor suppressor gene: An in silico approach
The phosphatase and tensin homolog (PTEN) gene plays a crucial role in signal transduction by negatively regulating the PI3K signaling pathway. It is the most frequent mutated gene in many human-related cancers. Considering ...
Profiling Deleterious Non-synonymous SNPs of Smoker-s Gene CYP1A1
CYP1A1 gene belongs to the cytochrome P450 family and is known better as smokers- gene due to its hyperactivation as a consequence of long term smoking. The expression of CYP1A1 induces polycyclic aromatic hydrocarbon ...
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