Publication: Unpredictable behavior of breast phyllodes tumors
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Date
2014-09-01
Authors
Akcakaya, ADEM
KOC, B.
EROZGEN, F.
Memmi, NAİM
HOT, S.
YILDIZ, M. K.
GUCIN, ZÜHAL
ADAS, G.
Kemik, Özgür
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Abstract
– OBJECTIVE: Phyllodes Tumor is a
rare fibroepithelial breast tumor with variable malignant potential. These tumors that currently accepted nomenclature are benign, borderline and
malignant according to the World Health Organization. It tends to behave in a benign way but it may
undergo a malignant transformation. The purpose
of this study was to present our Case load of phyllodes tumor, and evaluate the management and
follow-up the behavior of these tumors.
PATIENTS AND METHODS: 36 patients with
phyllodes tumor were treated in Bezmialem Vakif
University and Okmeydani Training and Research Hospitals analyzed retrospectively. Demographics, presenting symptoms, history, local
examination, preoperative clinical diagnosis,
treatment, postoperative histopatology, followup period were evaluated retrospectively and
studied.
RESULTS: A total of 36 patients treated for
phyllodes tumor were analyzed. Mean age of the
patients was 38 (14-79) and all were females. The
presentation of the patients was breast lump in
all cases, either as a primary or recurrent lump
presentation. The right and left breast were affected 58% and 42% respectively. 34 of these 36
cases are briefly mentioned in this paper but the
two cases, one with sarcomatous malignant
transformation and the other with fatal metastatic phyllodes tumor in an adolescent female are
discussed in detail. The mean duration of the
symptomatic mass was 9.8 ± 7.3 months (range
0.5 to 24).
CONCLUSIONS: Phyllodes tumor is a type of
tumor that may be benign or malignant. The type
with malignant features may be fatal. The tumors
diagnosed as benign may transform and become
malignant because of unknown reasons and
may be an aggressive tumor.
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Citation
Akcakaya A., KOC B., EROZGEN F., Memmi N., HOT S., YILDIZ M. K. , GUCIN Z., ADAS G., Kemik Ö., -Unpredictable behavior of breast phyllodes tumors-, EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.18, ss.2655-2661, 2014