Publication: Serum Melatonin Levels in Patients with Sudden Sensorineural Hearing Loss
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Date
2020-07-01T00:00:00Z
Authors
Baki, Ahmet
ÖZER, Ömer Faruk
Yildiz, Muhammet
KÖKTAŞOĞLU, FATMANUR
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Abstract
Objective: This study aimed to investigate the serum melatonin levels of patients with idiopathic sudden sensorineural hearing loss (ISSNHL).
Methods: This study enrolled 22 patients with ISSNHL and 22 asymptomatic healthy volunteers. The subjects underwent pure tone audiometry and serum melatonin levels were measured.
Results: The patient group was composed of 12 women (mean age, 46.41 +/- 7.8) and 10 men (mean age, 48 +/- 6.46), and the control group was composed of 12 women (mean age, 40.25 +/- 5.28) and 10 men (mean age, 38.4 +/- 27.08). The serum melatonin levels were significantly lower in the patient group than in the control group (p=0.001). A statistically significant strong negative correlation was found between serum melatonin level and severity of hearing loss (r=-0.644; p=0.001).
Conclusion: Serum melatonin levels of patients with ISSNHL were lower than controls. A statistically significant strong negative correlation was found between serum melatonin level and the severity of hearing loss.
Description
Keywords
Sudden hearing loss, melatonin, antioxidant
Citation
Baki A, Özer ÖF, Yıldız M, Köktaşoğlu F. Serum Melatonin Levels in Patients with Sudden Sensorineural Hearing Loss. Bezmialem Science 2020;8(3):269-74.