Publication: Dry Eye and Dry Nose Caused by the Effect of Allergic Rhinitis on Tear and Nasal Secretion Osmolarity.
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Date
2020-03-17T00:00:00Z
Authors
Elbay, A
Yenigun, A
Ozturan, O
Bayraktar, H
Ozer, Ömer Faruk
Dogan, R
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Abstract
Objective: Allergic rhinitis is a type 1 hypersensitivity reaction of immunoglobulin E in the rhino-ocular mucosa. This study was
planned to demonstrate in patients with allergic rhinitis to evaluate changes in tear, nasal secretions, and blood osmolarity compared to
healthy individuals. Method: Forty allergic rhinitis patients, 25 patients with acute upper respiratory tract infections, and 26 healthy
participants were included in the study. Positive patients with allergic symptoms and skin prick test results were included in the
allergic rhinitis group. Tear, nasal secretion, and blood osmolarity values were examined for the 3 groups. Result: In patients with
allergic rhinitis, tear and nasal secretion osmolarity values were significantly higher in patients with acute upper respiratory tract
infections and those of the healthy participants (P ¼ .001, P ¼ .038). In blood osmolarity measurements, there was no statistical
difference between the groups (P ¼ .489). In patients with allergic rhinitis, Schirmer test results were significantly shorter than
patients who had acute upper respiratory tract infection and those of the healthy participants (P ¼ .001, P ¼ .001). Patients with
allergic rhinitis and acute upper respiratory tract infections had significantly shorter Schirmer test results than in healthy participants (P ¼ .001, P ¼ .001). Conclusion: Tear osmolarity was increased in allergic rhinitis patients, and this was thought to lead
to dry eye findings. In the presence of allergic rhinitis, nasal secretions were found more hyperosmolar than tears. Nasal secretion
osmolarity was higher in allergic rhinitis patients than in patients with acute upper respiratory tract infections and control group.
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Citation
Yenigun A., Elbay A., Ozdem A., Bayraktar H., Ozer Ö. F. , Dogan R., Ozturan O., -Dry Eye and Dry Nose Caused by the Effect of Allergic Rhinitis on Tear and Nasal Secretion Osmolarity.-, Ear, nose, & throat journal, 2020