Metachronous metastatic paraganglioma in jejunum as a rare entity: A case report

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Date
2015-03-01Author
MUSLUMANOGLU, MahmutYARDIMCI, ERKAN
Arici, DİLEK SEMA
CIPE, Gokhan
Bektasoglu, HÜSEYİN KAZIM
KARATEPE, Oguzhan
HASBAHCECI, Mustafa
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Show full item recordAbstract
Pheochromocytomas and paragangliomas are
neuroendocrine tumors that arise from chromaffin cells of
adrenal medulla and extra-adrenal paraganglia, respectively.
The recurrence of these neuroendocrine tumors as a jejunal
mass causing obstruction in the small intestine is an exceptional
entity. The present study reports the case of a 70-year-old male
who presented to the Emergency Department of Bezmialem
Vakif University Hospital with abdominal pain and vomiting.
The patient possessed a history of left nephrectomy due to
malignant pheochromocytoma that had invaded into the left
kidney eight months prior to presentation. Bowel obstruction was diagnosed and the patient underwent a laparoscopic
procedure. Partial resection of the jejunum was performed
and immunohistochemical studies revealed the lesion to be
malignant paraganglioma. The majority of paragangliomas
are chemo- and radioresistant. Surgical excision remains the
primary treatment. Metachronous paraganglioma arising
from the small intestine is an extremely rare entity and may
be a relevant consideration in patients presenting with bowel
obstruction.
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