Now showing items 1-10 of 9074
Assessment of the antiproliferative and apoptotic roles of sulfonamide carbonic anhydrase IX inhibitors in HeLa cancer cell line
Carbonic anhydrase IX (CA IX) has recently been validated as an antitumor/antimetastatic drug target. In this study, we examined the underlying molecular mechanisms and the anticancer activity of sulfonamide CA IX ...
The application of molecular modelling studies to understand the selectivity and potency of several novel carbonic anhydrase inhibitors
The application of molecular modelling studies to understand the selectivity and potency of several novel carbonic anhydrase inhibitorsAtilla AkdemirComputer-Aided Drug Discovery Laboratory, Department of Pharmacology, ...
Effects of Intrathecai Verapamil on Cerebral Vasospasm in Experimental Rat Study
BACKGROUND: Verapamil a calcinarn channel blacker, has shown promising results on cerebral vasospasm. However, it has not yet been accepted for treatment or prevention purposes because of the associated side effects, ...
A retrospective study: Do all impacted teeth cause pathology?
Objective: The objective of this study is to determine the incidence of impacted teeth and the frequency of pathologies they caused by cone beam computed tomography (CBCT) retrospectively. Materials and Methods: In this ...