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Local Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis

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Date
2019-08-17
Author
Kiziltoprak, Hasan
Aycan, Zehra
Tekin, Kemal
Koc, Mustafa
Elmaogullari, Selin
Yilmaz, Aslihan Arasli
Inanc, Merve
Hekimoglu, Rumeysa
Advisor
Type
Article
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Abstract
Purpose: To evaluate the ocular surface characteristics based on Schirmer-s test, tear break-up time (TBUT), and conjunctival impression cytology (CIC) in children with Hashimoto-s thyroiditis (HT). Methods: This study included 51 children with HT and 53 control subjects. The ocular surface characteristics of participants were assessed via Schirmer-s test, TBUT, and CIC. Conjunctival samples were examined cytologically according to the Nelson grading system. Results: Schirmer-s and TBUT results were significantly lower in HT group (p < .05). All samples in both the study and control groups were evaluated as grade 0 according to the Nelson classification (p = .841), however, goblet cell density (GCD) was significantly lower in HT group (p = .001). Schirmer test results were significantly associated with the duration of HT (p = .025, r = -0.311). Conclusion: Hashimoto-s thyroiditis without any ocular complaints may cause ocular surface changes with TBUT and Schirmer-s. Although CIC analysis showed similar grading results, GCD was significantly decreased in HT group.
Subject
Kiziltoprak H., Koc M., Tekin K., Hekimoglu R., Inanc M., Yilmaz A. A. , Elmaogullari S., Aycan Z., -Local Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis-, OCULAR IMMUNOLOGY AND INFLAMMATION, 2019
URI
https://hdl.handle.net/20.500.12645/11143
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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS