Publication: The Impact of Admission Serum Creatinine Derived Estimated Glomerular Filtration Rate on Major Adverse Cardiac Events in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
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Date
2016-04-01
Authors
ULUGANYAN, MAHMUT
KARACA, GÜRKAN
ULUTAŞ, TÜRKER KEMAL
EKMEKÇİ, AHMET
BAKSHALİYEV, NİJAD
MURAT, AHMET
KÖROĞLU, BAYRAM
UYAREL, HÜSEYİN
EREN, MEHMET
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Abstract
Background: The impact of Cockroft-Gault (C-G) derived estimated glomerular filtration rate (eGFR) on mortality and major adverse cardiac events (MACEs) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) was assessed.
Methods: A total of 884 patients were classified into four categories according to admission creatine derived eGFR: < 60, 60 - < 90, 90 - < 120, and ≥ 120 mL/min/1.73 m(2).
Results: In-hospital and long-term MACEs were significantly higher in eGFR < 60 mL/min/1.73 m(2) subgroup (P < 0.001 and P = 0.028). Multivariate analysis demonstrated 7.78-fold (95% CI: 0.91 - 66.8) higher mortality risk in eGFR < 60 mL/min/1.73 m(2) subgroup.
Conclusion: As an easily applicable bedside method, C-G derived eGFR could be important for prediction of in-hospital and long-term mortality and MACE in STEMI patients undergoing primary PCI.
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Keywords
Cockcroft-Gault, Estimated glomerular filtration rate, Major adverse cardiac events, Mortality, ST-segment elevation myocardial infarction
Citation
ULUGANYAN M., KARACA G., ULUTAŞ T. K. , EKMEKÇİ A., TUSUN E., MURAT A., KÖROĞLU B., UYAREL H., BAKSHALİYEV N., EREN M., -The Impact of Admission Serum Creatinine Derived Estimated Glomerular Filtration Rate on Major Adverse Cardiac Events in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention-, Journal of Clinical Medicine Research, cilt.8, ss.325-330, 2016