Publication: Impact of admission blood glucose levels on prognosis of elderly patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention
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Date
2013-01-01
Authors
Authors
Ekmekci, Ahmet
Uluganyan, MAHMUT
Tufan, Fatif
Uyarel, Huseyin
Karaca, Gurkan
Kul, Seref
Gungor, Baris
Ertas, Gokhan
Erer, Betul
Sayar, Nurten
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Abstract
Objective: Admission hyperglycemia in acute myocardial infarction (MI) is related with increased in-hospital and long term mortality and major cardiac adverse events. We aimed to investigate how admission hyperglycemia affects the short and long term outcomes in elderly patients (> 65 years) after primary percutaneous coronary intervention for ST elevation myocardial infarction.
Methods: We retrospectively analyzed 677 consecutive elderly patients (mean age 72.2 ± 5.4). Patients were divided into two groups according to admission blood glucose levels. Group 1: low glucose group (LLG), glucose < 168 mg/dL; and Group 2: high glucose group (HGG), glucose > 168 mg/dL.
Results: In-hospital, long term mortality and in-hospital major adverse cardiac events were higher in the high admission blood glucose group (P < 0.001). Multivariate regression analysis showed: Killip > 1, post-thrombolysis in MI < 3 and admission blood glucose levels were independent predictors of in-hospital adverse cardiac events (P < 0.001).
Conclusions: Admission hyperglycemia in elderly patients presented with ST elevation myocardial infarction is an independent predictor of in-hospital major adverse cardiac events and is associated with in-hospital and long term mortality.
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Keywords
In-hospital mortality, Admission hyperglycemia, Elderly patients, Long-term mortality, Major adverse cardiac events
Citation
Ekmekci A., Uluganyan M., Tufan F., Uyarel H., Karaca G., Kul S., Gungor B., Ertas G., Erer B., Sayar N., et al., -Impact of admission blood glucose levels on prognosis of elderly patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention-, JOURNAL OF GERIATRIC CARDIOLOGY, cilt.10, ss.310-316, 2013