Person:
ÖZER, ÖMER FARUK

Loading...
Profile Picture
Google ScholarScopusORCIDPublons
Status
Organizational Units
Organizational Unit
Job Title
First Name
ÖMER FARUK
Last Name
ÖZER
Name
Email Address
Birth Date

Search Results

Now showing 1 - 3 of 3
  • PublicationMetadata only
    The changes of oxidative stress markers and vitamin E in patients with diabetes using SGLT2 inhibitors
    (2023-01-01) Buyukaydin B.; ÖZER Ö. F.; ÖZDER A.; YILDIZ C.; BÜYÜKAYDIN, BANU; ÖZER, ÖMER FARUK; ÖZDER, ACLAN; YILDIZ, CANER
    Objectives: This study aimed to research the diversities of vitamin E and oxidative stress parameters related to sodium-glucose transport protein 2 (SGLT2) inhibitor use by type 2 diabetes mellitus (T2DM) patients. Methods: This observational clinical study collected data from 67 T2DM patients (55.7±9.3 years, 46% female). Vitamin E, total oxidant status (TOS), total antioxidant status (TAS), total thiol, native thiol, myeloperoxidase, and catalase levels were evaluated. The TOS/TAS ratio was calculated as the oxidative stress index. Correlations of the parameters to each other and differences based on SGLT2 inhibitor use were recorded. Results: The mean hemoglobin A1c was 7.1 (5.5–13.1). SGLT2 inhibitors (all combinations) were used by 25 patients (37.3%). The mean level of vitamin E was 6 (3.6–9.8) mg/L. There was a positive correlation between vitamin E and low-density lipoprotein cholesterol (p<0.001). While there was no significant correlation between vitamin E and all included oxidative stress parameters, the level of vitamin E was statistically lower in patients using pioglitazone (p=0.036) and statins (p<0.001). In patients using SGLT2 inhibitors, fasting glucose, triglycerides, alanine aminotransferase, and the spot urine protein/creatinine ratio were significantly lower, and the mean TAS was higher (p<0.05). Conclusion: While no differences were observed in vitamin E and other oxidative parameters related to SGLT2 inhibitor use, the increase in TAS provides motivation for further research investigating the antioxidant properties of these inhibitors.
  • PublicationMetadata only
    Diagnostic and Prognostic Value of Pentraxin 3, Interleukin-6, CRP, and Procalcitonin Levels in Patients with Sepsis and Septic Shock
    (2024-03-01) Palalioǧlu B.; Erdoǧan S.; Atay G.; Tugrul H.; ÖZER Ö. F.; ÖZER, ÖMER FARUK
    Introduction and Purpose: In this prospective study, we aim to evaluate the effects of antibiotherapy on pentraxin-3 (PTX3), C-reactive protein (CRP), and interleukin-6 (IL-6) levels in patients with sepsis and septic shock. Materials and Methods: In our study, CRP, procalcitonin, IL-6, and PTX3 levels at initial and 48 hours of the antibiotherapy of patients who were admitted to the pediatric intensive care unit (PICU) with the diagnosis of sepsis and septic shock between June 2020 and March 2021 were compared. Patients were compared with the age-appropriate case-control group formed from the patients who received pre-operative routines to investigate the diagnostic value. Results: CRP, IL-6, and PTX3 levels of the patients were significantly higher compared to controls (P 32 pg/mL, 88.9% sensitivity, 65.6% specifity). Conclusion: The results of this study indicated that IL-6 level is an appropriate biomarker with high specificity in the diagnosis of sepsis and septic shock and in evaluating the response to treatment and determining the prognosis.