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ÖZER, ÖMER FARUK

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ÖMER FARUK
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Now showing 1 - 10 of 19
  • PublicationMetadata only
    Protective effect of dexpanthenol against nephrotoxic effect of amikacin: An experimental study
    (2017-05-01) Dogan, ELİF ECE; ERKOC, Reha; EKINCI, Iskender; HAMDARD, Jamshid; DONER, Baris; KARATOPRAK, CUMALİ; Coban, GANİME; Ozer, Omer Faruk; Kazancioglu, RÜMEYZA; DOĞAN, ELİF ECE; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZA
    Background: Amikacin has the largest spectrum among aminoglycosides, its nephrotoxic effect limits its utilization. Our purpose in this study is to review the protective effect of dexpanthenol against the nephrotoxic effect of amikacin, accompanied with histopathological and biochemical parameters.
  • PublicationMetadata only
    The predictive value of signal peptide-CUB-EGF domain-containing protein1 (SCUBE1) in terms of the duration of peripheral ischemia and exposure to reperfusion
    (2017-01-01) SÖĞÜT, Ozgur; Sonmez, ERTAN; YIGIT, Mehmet; Turkdogan, Kenan Ahmet; KUCUKDAGLI, Okkes Taha; YİĞİT, Eda; Ozer, Omer Faruk; CİVELEK, Cemil; SÖNMEZ, ERTAN; ÖZER, ÖMER FARUK
    Biomarkers play important roles in the diagnosis and follow-up of ischemic diseases. This study investigated the predictive value of signal peptide-CUB-EGF domain-containing protein1 (SCUBE1) in rats with peripheral ischemia that were subjected to reperfusion. Forty rats were divided into five equal groups as follows (eight rats per group): a control group (to determine the basal levels of the markers), three ischemia groups (groups 1-3), and a reperfusion group (group 4). There were no significant differences in SCUBE1 levels between the control and ischemia groups. However, the SCUBE1 level was markedly higher in the reperfusion group than in the control and ischemia groups (p<0.05). The results indicate that SCUBE1 levels are not biomarkers of the induction of ischemia. However, they are potentially markers of reperfusion in rats with acute peripheral occlusions.
  • PublicationOpen Access
    Comparison of the biochemical and radiological criteria for lumbar disc degeneration
    (2018-09-01) Seyithanoglu, MEHMET HAKAN; Kitis, SERKAN; Ozer, Omer Faruk; Kocyigit, ABDÜRRAHİM; DÜNDAR, Tolga; Papaker, Meliha Gundeg; SEYİTHANOĞLU, MEHMET HAKAN; KİTİŞ, SERKAN; ÖZER, ÖMER FARUK; KOÇYİĞİT, ABDÜRRAHİM
    Background: The relationship between radiological degeneration criteria on lumbar magnetic resonance imaging (MRI) and both the keratan sulfate (KS) and chondroitin sulfate (ChS) levels was examined in disc material taken from patients undergoing lumbar disc herniation (LDH) surgery. To examine whether the biochemical and radiological degeneration criteria testing the reliability of radiological degeneration findings agreed and to evaluate the contribution of the KS/ChS ratio to disc form (protruding or extruding).
  • PublicationMetadata only
    The diagnostic role of signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 in non-ST-elevation acute coronary syndrome
    (2015-01-01) Sonmez, ERTAN; TURKDOGAN, Kenan Ahmet; KARABACAK, Mustafa; CİVELEK, Cemil; YILMAZ, Cahit; Ozer, Omer Faruk; ÇAVUŞ, Umut Yucel; SÖNMEZ, ERTAN; ÖZER, ÖMER FARUK
    Objective: Chest pain and/or electrocardiogram changes in non-ST elevation or suspicious chest pain and cardiac marker elevations are defined as non-ST-elevation acute coronary syndrome (NSTE-ACS). Serial electrocardiogram and marker follow-up are needed to make a diagnosis of NSTE-ACS and to eliminate noncoronary chest pain (NCCP). Signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 (SCUBE1) is stored within the a granules of inactive platelets and secreted at a high rate during thrombosis. We believe that SCUBE1 may be a sensitive early diagnostic indicator in distinguishing coronary-induced chest pain from noncoronary-induced chest pain.
  • PublicationMetadata only
    Comparison of serum thiol-disulphide homeostasis and total antioxidant-oxidant levels between exudative age-related macular degeneration patients and healthy subjects
    (2017-10-01) Elbay, AHMET; Ozer, Omer Faruk; AKKAN, Julide Canan Umurhan; Celik, Ugur; KUTLUTURK, Isil; Koytak, Arif; OZDEMIR, Hakan; ELBAY, AHMET; ÖZER, ÖMER FARUK; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKAN
    The purpose of the study was to calculate serum total oxidant status (TOS), total antioxidant status (TAS), and dynamic thiol-disulphide (T-D) homeostasis in patients with age-related macular degeneration (AMD), and compare the results with healthy individuals.
  • PublicationMetadata only
    The Diagnostic Value of SCUBE1 in Unstable Angina Pectoris Patients
    (2016-12-01) OZKAN, Abuzer; Sonmez, ERTAN; OZDEMIR, Serdar; Ozer, Omer Faruk; MUHARREM, Nasifov; Gulen, BEDİA; KESKIN, Muhammed; SÖNMEZ, ERTAN; ÖZER, ÖMER FARUK; GÜLEN, BEDİA
    Aim: Signal peptide complement C1r/C1s, Uegf, and Bmp1-epidermal growth factor-like domain-containing protein 1 (SCUBE1) has been used in research as a biomarker in acute coronary syndrome (ACS). The aim of this study is to determine if SCUBE1 and routine laboratory parameters are effective in distinguishing the patients presenting with clinical symptoms of unstable angina pectoris (USAP) from the patients who have non-ST-segment elevated myocardial infarction (NSTEMI) and non-cardiac chest pain patients (NCCP).
  • PublicationMetadata only
    Pediatric reference intervals of free thyroxine and thyroid stimulating hormone in three different hospitals
    (2018-10-01) Aral, Hale; Ozer, Omer Faruk; Onur, Hatice; ÇİLİNGİRTÜRK, AHMET METE; Ozgen, Ilker Tolga; Ayyıldız, Mevlude; ÖZER, ÖMER FARUK; ÖZGEN, İLKER TOLGA
    Objective: Using data retrieved from three different hospitals, we established indirect reference intervals of free thyroxine (FT4) and thyroid stimulating hormone (TSH) for the Centaur XP or the Immulite 2000 instruments, in separate reference limits at each subset.
  • PublicationMetadata only
    Oxidative Stress Level in Patients with Subarachnoid Hemorrhage.
    (2021-12-12T00:00:00Z) Abdallah, Anas; Guler, Eray Metin; Çınar, İrfan; Papaker, Meliha Gündağ; Dündar, Tolga Turan; Yurtsever, İSMAİL; GUNDAG, MELİHA; ÖZER, ÖMER FARUK; YURTSEVER, İSMAİL; DÜNDAR, TOLGA TURAN
  • PublicationMetadata only
    Effects of Cichorium Intybus Extract on Seizure Development, Bcl-2, Siklin B1 ve beta-Tubulin Levels in Pentylenetetrazole-Kindling Model of Epilepsy in Rats
    (2015-09-01) Erkeç, Özlem Ergül; Meral, Ismail; Kara, Mehmet; Kocyigit, ABDÜRRAHİM; Armagan, Metin; Ozer, Omer Faruk; MERAL, İSMAİL; KOÇYİĞİT, ABDÜRRAHİM; ÖZER, ÖMER FARUK
  • PublicationMetadata only
    Do Low Serum UCH-L1 and TDP-43 Levels Indicate Disturbed Ubiquitin-Proteosome System in Autism Spectrum Disorder?
    (2017-09-01T00:00:00Z) Cetin, Ihsan; Tezdig, Ihsan; TARAKCLOGLU, Mahmut Cem; Kadak, Muhammed Tayyib; Demirel, Omer Faruk; Ozer, Omer Faruk; Erdogan, Firat; Dogangun, Burak; ÖZER, ÖMER FARUK
    Introduction: The mechanism of ubiquitination-related abnormalities causing neural development problems is still unclear. We examined the association between autism and serum transactive response DNAbinding protein-43 (TDP-43) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) levels, both of which are members of the ubiquitinproteosome system.