Person: İZZETTİN, FIKRET VEHBI
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Publication Metadata only Determination of CYP2C19 polymorphisms, adverse drug reaction, and medication adherence in patients utilized selective serotonin reuptake inhibitors(2015-02-01T00:00:00Z) Deniz, Semanur; SANCAR, MESUT; OKUYAN, BETÜL; ATA, PINAR; Bingol-Ozakpinar, Ozlem; TALAS, Anil; GUNES, Tufan; CALISKAN, Mecit; Izzettin, Fikret Vehbi; İZZETTİN, FIKRET VEHBIPublication Metadata only Assessment of pharmacy technicians- attitudes and responsibilities toward patient oriented pharmacy practices at community pharmacy(2012-02-01T00:00:00Z) SANCAR, MERT; OKUYAN, BETÜL; Tamyuksel, E.; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBIPublication Metadata only Assessment of attitude and knowledge in patients utilized disposable insulin pens at community pharmacy setting(2016-04-01T00:00:00Z) OKUYAN, BETÜL; Semerci, Z.; Odabasi, G.; Izzettin, FİKRET VEHBİ; SANCAR, MERT; İZZETTİN, FIKRET VEHBIPublication Metadata only Assessment of individuals- knowledge and attitudes towards utilization of analgesics at community pharmacy setting(2019-02-01T00:00:00Z) Torun, B.; ÖZKAN, ONUR CAN; Zortul, H.; Kesedar, S.; Izzettin, FİKRET VEHBİ; SANCAR, MERT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBIPublication Metadata only Impact of a pharmaceutical care program on glycemic control, medication knowledge and medication adherence levels of type 2 diabetic patients residing at a nursing home(2017-02-01T00:00:00Z) Saglam, Nimet; Apikoglu-Rabus, Sule; OKUYAN, BETÜL; Izzettin, Fikret V.; Yildirim, NURAN; İZZETTİN, FIKRET VEHBIPublication Metadata only Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats(2017-09-01T00:00:00Z) Bami, Erliasa; Ozakpinar, Ozlem Bingol; Ozdemir-Kumral, Zarife Nigar; Koroglu, Kutay; ERCAN, FERİHA; CIRAKLI, Zeynep; ŞEKERLER, TURGUT; Izzettin, FİKRET VEHBİ; SANCAR, MESUT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBIThis study aims to determine the potential protective effects of ferulic acid against cisplatin-induced nephrotoxicity and to compare its effect with curcumin, a well-known protective agent against cisplatin- induced toxicity in rats. Administration of cisplatin resulted in high BUN (Blood Urea Nitrogen), creatinine, MDA (Malondialdehyde), MPO (Myeloperoxidase), TOS (Total Oxidative Status), PtNT (Protein Nitrotyrosine) levels (p < 0.05). Histological observations showed abnormal morphology of kidney; in addition with appearance of TUNEL positive cells indicating apoptosis in cisplatin administered group. HO-1 (Heme Oxygenase-1) levels measured by RT-PCR (Real Time Polymerase Chain Reaction), and TAS (Total Antioxidative Status) revealed antioxidant depletion due to cisplatin toxicity in animals (p < 0.05). All parameters showed improvement in groups treated with ferulic acid (p < 0.05). Ferulic acid treatment was found significant in preventing oxidative stress, increasing antioxidative status and regaining histological parameters to normal, indicating nephroprotective and antioxidant effects of this phenolic compound.Publication Metadata only Characteristics of the drug-disease information service demanded from the community pharmacist(2011-04-01T00:00:00Z) APIKOGLU-RABUS, S.; Pakalpakcil, O.; OKUYAN, BETÜL; SANCAR, MERT; Soydeger-Carli, B.; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBIPublication Open Access Determination of Potential Drug-Drug Interactions Using Various Software Programs in a Community Pharmacy Setting(2019-03-01T00:00:00Z) SANCAR, MESUT; Kasik, Aksa; OKUYAN, BETÜL; Batuhan, Sevda; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBIObjectives: The aim of the present study was to compare various software programs in detecting potential drug-drug interactions in a community pharmacy setting. Materials and methods: Details of prescriptions were collected from 50 community pharmacies located in İstanbul in March and April 2015 (two days per week). From each pharmacy, the first 20 prescriptions that included more than one drug were collected to evaluate potential drug-drug interactions. The following software programs were utilized to detect potential drug-drug interactions: micromedexsolutions.com, medscape.com, and drugs.com. The number of potential interactions detected by the software programs was determined. Results: At least one potential drug-drug interaction was detected in 39.2% of the 1000 prescriptions by one of the software programs. According to the rates of total drug-drug interactions gathered from various software programs, these programs gave the following results: medscape.com 33.3%, drugs.com 31.3%, and micromedexsolutions.com 21.2%. Conclusion: After comparing different software programs, the potential drug-drug interactions found by the programs proved to be different. Therefore, we recommend that pharmacists confirm with a different program before making a decision when they detect clinically significant potential drug-drug interactions.Publication Metadata only Importance of medication dose adjustment in hospitalized patients with impaired renal function at internal medicine ward: the possible impact of clinical pharmacist(2018-02-01T00:00:00Z) Altan, Aysenur; Ozkan, Oznur; DEMIRTUNC, Refik; OKUYAN, BETÜL; Izzettin, Fikret Vehbi; SANCAR, MESUT; İZZETTİN, FIKRET VEHBIPublication Metadata only Evaluation of drug burden index and medication utilization in geriatric patients at community pharmacy(2015-02-01T00:00:00Z) SANCAR, MESUT; Girgin, Irem; Selcuk, Aysu; Yang, Seonkyeong; Izzettin, Fikret Vehbi; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBI