Person:
SELEK, ŞAHABETTİN

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ŞAHABETTİN
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SELEK
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Now showing 1 - 7 of 7
  • PublicationMetadata only
    Investigation of Oxidative Stress Markers in the Pathogenesis of the Lung, Breast and Colon Cancer
    (2017-09-23T00:00:00Z) ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; SELEK, ŞAHBETTİN; ÇOBAN, GANİME; TÜRK, HACI MEHMET; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; SELEK, ŞAHABETTİN; ÇOBAN, GANİME; TÜRK, HACI MEHMET
  • PublicationOpen Access
    Paraoxonase-1 Phenotype and Its Relationship with Mean Platelet Volume and Oxidative Stress in Coronary Artery Disease
    (2015-09-01) SELEK, ŞAHBETTİN ; ÖZER, ÖMER FARUK ; GOKTEKİN, Omer ; KOÇYİĞİT, ABDÜRRAHİM; KALINBACOGLU, Ceren; ISLEK, Irem ; ISLEK, Tuğba; ARPACI, Beyza; Erol, Neval; MEYDAN, Sedat; GÜLER, ERAY METİN; SELEK, ŞAHABETTİN; ÖZER, ÖMER FARUK; KOÇYİĞİT, ABDÜRRAHİM; MEYDAN, SEDAT; GÜLER, ERAY METİN
    Objective: Paraoxonase-1 (PON1) 192 QR polymorphism is believed to be an important protective factor for coronary artery disease (CAD); oxidative stress plays a key role in the development of atherosclerotic CAD. Mean platelet volume (MPV) is also central to the processes, including pathophysiology of CAD and endothelial dysfunction. Thus, we aimed to determine the PON1 phenotype, MPV, and oxidative stress parameters in patients with angiographically proven CAD and to compare them with those in healthy subjects. Methods: Fifty-five CAD patients were diagnosed according to the angiography results, and 37 healthy subjects were present in this study. Serum paraoxonase and arylesterase activities were spectrophotometrically measured. Phenotype distribution was evaluated by the salt-stimulated paraoxonase activity according to arylesterase activity. Oxidative stress markers were evaluated by measuring serum total oxidant status (TOS) and total antioxidant status (TAS) as well as oxidative stress index. Results: In this study, the ratio of salt-stimulated paraoxonase/ OSI levels (S-PON1/OSI) were lower in the CAD patients and the differences were statistically significant (p<0.05). Therefore, the ratio of salt-stimulated paraoxonase/MPV (S -PON1/MPV) and S- PON1/OSI level were significantly different in the CAD patients as compared with controls group (p<0.01). Conclusion: Our study has suggested that S-PON1/OSI and SPON1/ MPV may play a significant role in CAD. To the best of our knowledge, the present study is the first to study the relationship among PON1 phenotype, MPV, and OSI in CAD patients. Thus, lowering of the oxidative stress and the regulation of MPV strategies may be a promising approach for the treatment of CAD.
  • PublicationMetadata only
    Raftlin, presepsin levels and thiol-disulfide homeostasis in acute appendicitis: A pilot study
    (2018-11-01) KOÇYİĞİT, ABDÜRRAHİM; ERSOY, YELİZ EMİNE; SELEK, ŞAHBETTİN; SÜMBÜL, BİLGE; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; MERAL, İSMAİL; YİĞİT, MEHMET; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; MERAL, İSMAİL; SÜMBÜL, BİLGE; SELEK, ŞAHABETTİN; ERSOY, YELIZ EMINE
    Objective: To investigate some of the new inflammatory and oxidative stress markers in acute appendicitis.
  • PublicationMetadata only
    Çörek Otu Yağının Sıçan Major Tükürük Bezlerinde ve Kan Parametrelerinde Radyoprotektif Etkileri
    (2016-10-30T00:00:00Z) Canpolat, Mustafa Salih; ŞAHİN YILMAZ, AYŞE ASLI; OYSU, ÇAĞATAY; GÜLER, ERAY METİN; SELEK, ŞAHBETTİN; Eriş, Ali Hikmet; MAYADAĞLI, ALPASLAN; TOK, OLGU ENİS; EŞREFOĞLU, MUKADDES; GÜLER, ERAY METİN; SELEK, ŞAHABETTİN; MAYADAĞLI, ALPASLAN; EŞREFOĞLU, MUKADDES
  • PublicationMetadata only
    Romatoid Artritli Hastalarda DMARD Kullanımının Hastalık Aktivitesi ve Oksidatif Markerları Üzerine Etkisi
    (2015-04-26T00:00:00Z) AYDIN, TEOMAN; TAŞPINAR, ÖZGÜR; KEPEKÇİ, MÜGE; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; SELEK, ŞAHBETTİN; ÇAMLI, AHMET ADİL; AYDIN, TEOMAN; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; SELEK, ŞAHABETTİN; ÇAMLI, AHMET ADİL
  • PublicationMetadata only
    Akciğer, meme ve kolon kanserli hastalarda oksidatif stres parametrelerinin değişimi
    (2019-01-01) ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; SELEK, ŞAHBETTİN; ÇOBAN, GANİME; KOÇYİĞİT, ABDÜRRAHİM; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; SELEK, ŞAHABETTİN; ÇOBAN, GANİME; KOÇYİĞİT, ABDÜRRAHİM
  • PublicationMetadata only
    Parkinson Hastalığında Oksidan ve Antioksidan Döngünün Değerlendirilmesi
    (2016-05-21T00:00:00Z) GÜLER, ERAY METİN; Uçak, Sinem; UÇKAYA, FATİH; Güneş, Halit Enes; BORUCU, MAKBULE DENİZ; SELEK, ŞAHBETTİN; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; SELEK, ŞAHABETTİN; KOÇYİĞİT, ABDÜRRAHİM