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ÜNVER, NURCAN

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NURCAN
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ÜNVER
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Now showing 1 - 10 of 14
  • PublicationMetadata only
    Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases.
    (2019-04-01) UNVER, NURCAN; COBAN, GANİME; ARıCı, DİLEK SEMA; BUYUKPıNARBASıLı, NUR; Gucin, ZÜHAL; MALYA, FATMA ÜMİT; ONARAN, OI; TOPALAN, K; ÜNVER, NURCAN; ÇOBAN, GANİME; ARICI, DILEK SEMA; BÜYÜKPINARBAŞILI, NUR; GÜCİN, ZÜHAL; MALYA, FATMA ÜMİT
  • PublicationMetadata only
    Differential expression of P16 and P21 in benign and malignant uterine smooth muscle tumors
    (2011-08-01T00:00:00Z) Unver, NURCAN; Acikalin, Mustafa Fuat; Oner, Ulku; Ciftci, Evrim; Ozalp, S. Sinan; Colak, Ertugrul; ÜNVER, NURCAN
    The diagnosis of benign and malignant uterine smooth muscle tumors depends on morphologic criteria such as nuclear atypia, coagulative tumor cell necrosis and mitotic activity. Most of these tumors are readily classifiable into benign or malignant categories using these criteria. However, the distinction between leiomyomas and leiomyosarcomas may at times be problematic. Hence, it would be useful to have additional markers which could help to distinguish these tumors. The aim of the study was to evaluate p16 and p21 expressions in uterine smooth muscle tumors and determine whether p16 and p21 have a potential value in the differential diagnosis of problematic cases. In addition, we evaluated whether the differential expression of p16 and p21 in uterine leiomyosarcomas correlated with tumor recurrence and patient survival.
  • PublicationMetadata only
    Relationship between the poor glycemic control and risk factors, life style and complications.
    (2017-01-01T00:00:00Z) KAYAR, Yusuf; ILHAN, Aysegul; KAYAR, Nuket Bayram; Unver, NURCAN; Coban, GANİME; EKINCI, Iskender; HAMDARD, Jamsid; PAMUKCU, Ozgul; EROGLU, Hatice; ÜNVER, NURCAN; ÇOBAN, GANİME
    It has shown that the decrease of blood glucose levels in patient with diabetes mellitus decreases mortality and morbidity rates. Main purpose in diabetes is to achieve and prevent the glycemic control. We aimed to evaluate the relationship between poor glycemic control and metabolic parameters, individual life and complications. Seven hundred fifty seven patients with type II diabetes mellitus have evaluated with demographical characteristic, body mass index, abdominal circumferences, blood pressures, dietary compliances, physical exercise statuses and laboratory analysis; and the relationship of these parameteres were investigated. Poor glycemic control was found significantly associated with duration of diabetes, age of onset, family history, job status, educational status, antidiabetic drugs, body mass index, abdominal circumference, hypertension, lipid and fasting plasma glucose levels. There was a significant relationship between the glycemic control and dietary compliance, physical activity, self blood glucose monitoring and drug compliance. While there is a significant relationship between the poor glycemic control and nephropathy, retinopathy, neuropathy and cardiovascular diseases; no significant relationship was seen in the cerebrovascular diseases and arthropathy. We have pointed the relationship of glycemic control with sociodemographic, medical status, life style, lipid levels and complications. Better results can be obtained by eliminating the factors related to poor glycemic control.
  • PublicationOpen Access
    Co-existence of acute appendicitis and inflammatory myofibroblastic tumor of the small intestine: A case report
    (2015-09-01) Unver, NURCAN; Coban, GANİME; ONARAN, Oyku Izel; ARSLAN, ADNAN; Malya, FATMA ÜMİT; HASBAHCECI, Mustafa; ÜNVER, NURCAN; ÇOBAN, GANİME; KUNDUZ, ENVER; ARSLAN, ADNAN; MALYA, FATMA ÜMİT
    Introduction: Inflammatory myofibroblastic tumor as a rare neoplastic lesion is seen most commonly in the pulmonary system. Beside the presence of limited number of inflammatory myofibroblastic tumors of the gastrointestinal tract in the literature, co-existence with acute appendicitis has not been reported before. Presentation of case: A 27-year-old woman admitted to emergency department with acute abdominal pain at the right lower quadrant. The initial diagnosis was as acute appendicitis. Intraoperatively, a mass with a diameter of almost 5 cm originated from the distal ileal segments neighboring the appendix was seen. The patient was managed by segmental resection of the small intestine including the mass with appendectomy. Histologically, there were bundles of spindle cells accompanied by lymphoplasmocytic infiltration. The immunohistochemical studies showed that tumor cells were positive for smooth muscle actin, vimentin, perinuclear activity for anaplastic lymphoma kinase and CD 68. The final pathologic diagnosis was inflammatory myofibroblastic tumor. Discussion: Concomitant resection of tumoral lesions detected in the neighbor intestinal segments during appendectomy should be considered to diagnose and treat. For the diagnosis of inflammatory myofibroblastic tumor, immunohistochemistry pattern including positivity for actin, vimentin, CD 68 and anaplastic lymphoma kinase plays a crucial role. Therefore, detailed immunohistochemistry analysis should be performed in suspicious cases. Conclusion: Coexistence of inflammatory myofibroblastic tumor located in the gastrointestinal system with acute appendicitis is a rare event. Complete surgical excision should be regarded as the mainstay of the treatment. Long-term follow up with serial imaging techniques is recommended.
  • PublicationMetadata only
    Spinal cord ischemia after endoscopic ultrasound guided celiac plexus neurolysis: case report and review of the literature
    (2017-01-01) Koker, Ibrahim Hakki; Aralasmak, AYŞE; Unver, NURCAN; Asil, TALİP; Senturk, HAKAN; KÖKER, İBRAHİM HAKKI; ARALAŞMAK, AYŞE; ÜNVER, NURCAN; ASİL, TALIP; ŞENTÜRK, HAKAN
    Introduction: Endosonography guided celiac plexus neurolysis is efficacious in the management of severe pain due to advanced pancreatic cancer. Although endoscopic ultrasound (EUS) guided celiac neurolysis (CN) is mostly a safer procedure than the percutaneous posterior approach, severe complications such as paraplegia have been reported.
  • PublicationMetadata only
    Biphasic malignant mesothelioma of the testis: Case report.
    (2017-03-01) ARMAĞAN, ABDULLAH; ÇOBAN, GANİME; ÜNVER, NURCAN; KIZILTAN, HURİYE ŞENAY; GÜCİN, ZÜHAL; ÇOBAN, GANİME; ÜNVER, NURCAN; KIZILTAN, HURİYE ŞENAY
  • PublicationMetadata only
    EUS-guided FNA of a portal vein thrombus in hepatocellular carcinoma
    (2015-06-01T00:00:00Z) Kayar, Yusuf; Turkdogan, Kenan Ahmet; Baysal, Birol; ÜNVER, NURCAN; Danalioglu, Ahmet; ŞENTÜRK, HAKAN; ÜNVER, NURCAN; ŞENTÜRK, HAKAN
    Portal vein thrombosis is a relatively rare but well-known complication of cirrhosis that has a prevalence of between 1% and 5.7%. On the contrary, in case of hepatocellular carcinoma (HCC), it is a much more frequent complication. In this paper, we presented three cases that had liver cirrhosis, mass and portal vein thrombosis in liver. We were not able to diagnose the cases through imaging methods, laboratory results or histopathologically, however, they were diagnosed with endoscopic ultrasonography-fine needle aspiration EUS-FNA from portal vein thrombus.
  • PublicationMetadata only
    Evaluation of solid pseudopapillary tumor of the pancreas: One tertiary center experience
    (2018-01-01) KAYAR, Yusuf; Unver, NURCAN; ÇOBAN, GANİME; GÜCİN, ZÜHAL; EKINCI, Iskender; EMEGIL, Sebnem; KAYAR, Nuket Bayram; BAYSAL, Birol; BUGDACI, Mehmet Sait; ŞENTÜRK, HAKAN; ÜNVER, NURCAN; ÇOBAN, GANİME; GÜCİN, ZÜHAL; ŞENTÜRK, HAKAN
  • PublicationMetadata only
    Clinical evaluation of simultaneous integrated boost in brain metastasis patients with helical intensity modulated radiotherapy
    (2018-04-01) KIZILTAN, HURİYE ŞENAY; ERIS, A.H.; MERAL, İSMAİL; SEYITHANOGLU, H.; DÜNDAR, TOLGA TURAN; EREN, F.; UNVER, NURCAN; AYDIN, TEOMAN; MAYADAĞLI, ALPASLAN; BAYIR, A.G.; CELIKTEN, M.; KIZILTAN, HURİYE ŞENAY; MERAL, İSMAİL; DÜNDAR, TOLGA TURAN; TEKÇE, ERTUĞRUL; ÜNVER, NURCAN; AYDIN, TEOMAN; MAYADAĞLI, ALPASLAN
    Background: This study was performed to assess patient survival and treatment toxicity after helical tomotherapy (HT) with simultaneous integrated boost (SIB) radiotherapy (RT) for cancer patients with one to eight brain metastases (BM) who have been treated with or without surgery. Materials and Methods: A total of 48 brain metastasis (BM) patients were included in this retrospective study between April 2015 and December 2016,. The patients were treated with image-guided intensity modulated radiation therapy (IMRT) on the helical tomotherapy (HT) machine. Whole brain HT as 25 Gy and SIB to metastasis sites as 35 Gy was delivered in 10 fractions. The patient were aged between 50 to 80 years old, volume of the BM was between 6 to 75 cc and the number of brain metastasis was between 1 to 8, Karnofsky Performance Score (KPS) ranged between 50-90 and RPA I-III. Surgery was performed to two patients before RT. The maximum patient follow-up time was 20 months. Results: The primary neurotoxicity observed in patients was grade I- II brain edema related headache and lethargy. In patients who had survived 3- 12 months, KPS improved median score of 20 points and RPA was grade I after six months. Twelve patients had passed away at the end of a 20- month follow-up. Conclusion: HT utilizing SIB treatment for 1- 8 BM was achieved successfully with no significant toxicity. An improvement of performance status indicators of patients following RT was observed.
  • PublicationOpen Access
    A Primary Adenosquamous Carcinoma of the Stomach: Report of Two Cases
    (2017-07-01) Gecer, MELİN; Unver, NURCAN; HASBAHCECI, Mustafa; Gucin, ZÜHAL; Tosuner, ZEYNEP; Akcakaya, ADEM; Arici, Sema; GEÇER, MELİN; ÜNVER, NURCAN; GÜCİN, ZÜHAL; TOSUNER, ZEYNEP; ÇOBAN, EZGİ; AKÇAKAYA, ADEM; ARICI, DILEK SEMA
    Primary gastric adenosquamous carcinomas are extremely rare tumors. A gradual transition between the malignant glandular and squamous components of the tumor is seen on performing a histopathological evaluation. These tumors are known to have poorer clinical outcomes than conventional adenocarcinomas. We aimed to present two cases of primary adenosquamous carcinomas that were diagnosed at the later stage in our institute.