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GÖKÇAL, ELİF

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ELİF
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GÖKÇAL
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Now showing 1 - 10 of 16
  • PublicationMetadata only
    Essential Tremor and Alexithymia
    (2018-10-01) ŞENGÜL, YILDIZHAN; ŞENGÜL, HAKAN SERDAR; GÖKÇAL, ELİF; ÜSTÜN, İSMET; ÖZTÜRK, AHMET; YILMAZ, ONUR; YILDIZ, GÜLSEN; ŞENGÜL, YILDIZHAN; GÖKÇAL, ELİF; ÜSTÜN, İSMET; ÖZTÜRK, AHMET; YILMAZ, ONUR
  • PublicationMetadata only
    Evaluation of retinal alterations in Parkinson disease and tremor diseases.
    (2019-11-02T00:00:00Z) TUĞCU, BETÜL; Arif, Melikov; Babacan, Yildiz Gulsen; Gokcal, Elif; Ercan, Rukiye; UYSAL, ÖMER; Ozdemir, Hakan; TUĞCU, BETÜL; BABACAN YILDIZ, GÜLSEN; GÖKÇAL, ELİF; ERCAN, RUKIYE; UYSAL, ÖMER; ÖZDEMİR, MEHMET HAKAN
    Optical coherence tomography (OCT) has been suggested as a method for detection of retinal alterations in neurodegenerative diseases. The usefulness of OCT as a diagnostic tool to differentiate Parkinson-s disease (PD) from other tremor diseases, remains unknown. We aimed to evaluate morphological changes of the retina in patients with PD, essential tremor (ET), essential tremor-Parkinson-s disease (ET-PD) using OCT. Forty-two eyes of 21 patients with PD, 24 eyes of 12 patients with ET, 24 eyes of 12 patients with ET-PD and 44 eyes of 22 age-matched healthy controls were included in the study. All participants underwent detailed neurological and ophthalmological examination. Measurements in all quadrants of macula and retinal nerve fiber layer (RNFL) thickness using OCT were recorded. There was no significant difference among the groups regarding age, sex. The average RNFL thickness was thinner in PD patients than that of ET (p = 0.032). The RNFL thickness in superior quadrant was lower in PD group compared with the ET and control group (p = 0.001, p = 0.016). Significant differences were observed in most of the macular thickness parameters excluding foveolar and foveal thickness (p = 0.865, 0.394). Correlations were found among several OCT parameters and disease duration or severity in all patient groups (p > 0.05). Retinal alterations were found in PD patients compared to ET. However, no significant retinal changes were detected by OCT in patients with ET and ET-PD compared to controls. According to our data, retinal assessments by OCT do not seem to be satisfactory for differentiation of these disorders.
  • PublicationMetadata only
    . Kronik migrende ak madde lezyonları orta serebral arter ortalama akım hızları ve vasküler reaktivite ile ilişkili midir?
    (2017-11-30) USLU, FERDA; GÖKÇAL, ELİF; ŞENGÜL, YILDIZHAN; KARAKAYALI, ZEHRA CEMRE; UZUN, MUSTAFA; ASIL, TALİP; GÖKÇAL, ELİF; ŞENGÜL, YILDIZHAN; KARAKAYALI, ZEHRA CEMRE; USLU, FERDA; ASİL, TALIP
  • PublicationMetadata only
    Coexistence of autoimmune diseases and autoantibodies in patients with myasthenia gravis.
    (2016-01-01T00:00:00Z) TAMER, S; Gokce, Gunes; Gokcal, ELİF; YOLDAS, TK; GÖKÇAL, ELİF
  • PublicationOpen Access
    Motor and Non-Motor Symptoms in Parkinson-s Disease: Effects on Quality of Life.
    (2017-06-01) GÖKÇAL, ELİF; GÜR, VE; SELVITOP, R; Babacan, Yildiz; ASIL, TALİP; GÖKÇAL, ELİF; BABACAN YILDIZ, GÜLSEN; ASİL, TALIP
    Introduction: This study aimed to evaluate motor and non-motor symptoms in idiopathic Parkinson's disease (IPD) patients and to determine the self-reported influence of all existing symptoms on their quality of life (QoL). Methods: The sociodemographic and clinical characteristics, medical treatments, and Modified Hoehn and Yahr (mH&Y) scores of IPD patients without cognitive impairment were recorded. A survey questioning different motor and non-motor symptoms was administered to the patients. The patients were asked to rate their symptoms by number from the greatest influence to the least influence on their QoL. Subjects were divided into two groups: those suffering from IPD for ≤5 years (Group 1) and those suffering from IPD for >5 years (Group 2). These groups were compared in terms of sociodemographic and clinical characteristics, existing symptoms, and influences of these symptoms on their QoL. Results: There were 63 patients in Group 1 and 37 patients in Group 2. No statistically significant differences were detected between the groups with respect to sociodemographic characteristics or mH&Y scores. The most common motor symptoms in both of these groups were tremor and bradykinesia; meanwhile, the non-motor symptoms most frequently encountered in these groups were pain-cramps, constipation, and excessive daytime sleepiness (EDS). Again, while the symptoms that most greatly disturbed QoL in all patients were reported to be tremor and bradykinesia, the most disturbing non-motor symptom was frequent voiding/incontinence, which was a less common symptom. Pain-cramp, constipation, and EDS, which were the most frequent non-motor symptoms, were the symptoms that least disturbed QoL. Conclusion: It is widely accepted that motor symptoms determine QoL in IPD. However, non-motor symptoms are seen during all phases of the disease. The impact of non-motor symptoms on the QoL of IPD patients remains substantial. Therefore, in addition to the well-known motor symptoms, non-motor symptoms, which may be overlooked during physical examination yet may profoundly impact QoL, should be questioned and treated appropriately to improve QoL in PD patients as much as possible.
  • PublicationOpen Access
    Lambert-Eaton Myasthenic Syndrome with A Twenty-Three-Year Delay in Diagnosis
    (2017-06-01) Gokcal, ELİF; Gürsoy, AZİZE ESRA; Asil, TALİP; Ertas, Mustafa; GÖKÇAL, ELİF; GÜRSOY, AZIZE ESRA; ASİL, TALIP
    Lambert-Eaton myasthenic syndrome (LEMS) is a rare neuromuscular junction disorder resulting from the development of auto-antibodies against voltage-gated calcium channels (VGCCs) in pre-synaptic terminals (1). It has tumoral and non-tumoral forms; the former is associated with small cell lung cancer. Clinically, it is characterized by proximal weakness, autonomic symptoms, and loss/reduction of deep tendon reflexes (2). Muscular weakness, frequently occurring in the lower extremities, almost always begins symmetrically in the proximal muscles, progressing to involve the distal muscles over time (3). It may be confused with myopathic disorders due to the presence of symmetrical muscular weakness involving the proximal muscles. Herein we present the case of a non-tumoral LEMS patient who was diagnosed as having myopathy due to weakness that started in the legs nearly 23 years ago. Written consent was taken from the patient
  • PublicationMetadata only
    ETIOLOGICAL CLASSIFICATION OF ISCHEMIC STROKE IN YOUNG PATIENTS: A COMPARATIVE STUDY OF TOAST, CCS AND ASCO
    (2016-10-01) GOKCAL, ELİF; NIFTALIYEV, E.; Asil, TALİP; GÖKÇAL, ELİF; ASİL, TALIP
  • PublicationMetadata only
    PROLONGED HYPOTENSION AFTER CAROTID ARTERY STENTING: INCIDENCE, PREDICTORS AND CONSEQUENCES
    (2016-10-01) GOKCAL, ELİF; NIFTALIYEV, E.; DENIZ, C.; ERGELEN, M.; GUZEL, VİLDAN; GOKTEKIN, O.; Asil, TALİP; GÖKÇAL, ELİF; DENİZ, ÇİĞDEM; GÜZEL, VİLDAN; ASİL, TALIP
  • PublicationMetadata only
    Risk Factors, Etiological Classification, Topographical Location, and Outcome in Medullary Infarctions
    (2017-07-01T00:00:00Z) GÖKÇAL, ELİF; Baran, Gode; Niftaliyev, Elvin; GÜZEL, Vildan; ASİL, Talip; GÖKÇAL, ELİF; GÜZEL, VİLDAN; ASİL, TALIP
    An understanding of the etiological mechanisms is important for therapeutic decisions and prognostic evaluation of patients with ischemic stroke. The object of this study was to evaluate the risk factors, etiological subtypes, and topography of lesion in patients with medullary infarctions (MIs). Besides, we also investigated early neurological deterioration, new vascular events, and functional outcome of all patients at 3-month follow-up. We analyzed our database consisting of patients who were diagnosed with acute MI and who were admitted within 24 hours of onset. Etiological classification of stroke was made on the basis of the Trial of Org 1972 in Acute Stroke Treatment criteria. All of the infarctions were grouped into anteromedial, anterolateral, lateral, and posterior arterial territories and also categorized into those involving the upper, middle, or lower medulla oblongata. Early neurological deterioration, major vascular events within the first 3 months of follow-up and modified Rankin Score at 3 months were reviewed. A total of 65 patients with medullary infarctions were reviewed. Involved arterial territories differed according to the etiological classification. Large artery atherosclerosis was the most common etiological subtype; however, small vessel disease was the most common subtype in medial MIs. The lesions involving the anteromedial territory were common in the upper medullary region, whereas the lesions involving the posterior and lateral territories were common in the lower medulla oblangata. Recurrent stroke was seen in the posterior and lateral territories; however, early progression and poor functional outcome were mostly seen in lesions involving the anteromedial territories.
  • PublicationOpen Access
    Multiple Spontaneous Intracranial-Extracranial Arterial Dissections in a Patient with Osteogenesis Imperfecta
    (2017-01-01T00:00:00Z) KOLUKISA, MEHMET; GÖKÇAL, ELİF; GÜRSOY, Azize Esra; DENİZ, ÇİĞDEM; ARALAŞMAK, Ayşe; ASİL, Talip; KOLUKISA, MEHMET; GÖKÇAL, ELİF; GÜRSOY, AZIZE ESRA; DENİZ, ÇİĞDEM; ARALAŞMAK, AYŞE; ASİL, TALIP
    A 40-year-old male with osteogenesis imperfecta (OI) was admitted to the hospital with an acute right monoparesis. Diffusion-weighted MRI showed infarction in the territory of the left anterior cerebral artery (ACA) and in the left posterior cerebral artery (PCA). In his vascular imaging, occlusion of the left vertebral artery (VA) starting from V2 segment was consistent with dissection and pseudoaneurysm in the right ACA. We presented this case because of the presence of spontaneous and simultaneous occurrence of both intracranial and extracranial arterial dissections in OI.