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BAHALI, ANIL GÜLSEL

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ANIL GÜLSEL
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BAHALI
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Now showing 1 - 9 of 9
  • PublicationOpen Access
    The relationship between pruritus and clinical variables in patients with psoriasis
    (2017-07-01) Su, Ozlem; Bahali, ANIL GÜLSEL; Onsun, NAHİDE; OZKAYA, Dilek Biyik; Dizman, DİDEM; TOPUKCU, Bugce; Uysal, Omer; BAHALI, ANIL GÜLSEL; ONSUN, NAHIDE; SU KÜÇÜK, ÖZLEM; DİZMAN, DİDEM; UYSAL, ÖMER
    Pruritus is the most commonly occurring subjective symptom of dermatological disease. Published data on both prevalence and intensity of pruritus in psoriasis is limited. Objective: In this study we aimed to investigate the prevalence of pruritus and its relation with psoriasis area severity index, body mass index and presence of systemic disease in patients with psoriasis. Methods: We analyzed data of psoriatic patients diagnosed in our psoriasis outpatient clinic between March 2013 and June 2014 collected retrospectively from PSR-TR registration system. Results: In total, 880 patients were analyzed. Pruritus was more prominent in female patients. This difference was statistically significant. No significant associations were found between age of patients, clinical type of disease and pruritus. The itching was more common in patients with higher body mass index. Presence of pruritus was correlated significantly with severity of psoriasis. Five hundred and sixty of 880 patients had no systemic disease. The presence of pruritus was not related with presence of systemic disease. Existence of systemic disease with psoriasis has minimal effect on pruritus. Study Limitations: We did not evaluate intensity of pruritus. Conclusions: Pruritus is not mentioned within the classical symptoms of psoriasis. Pruritus in psoriasis is a very unpleasant symptom with great potential to impair patient’s quality of life and may exacerbate psoriasis as a Koebner phenomenon. Keywords: Patients; Psoriasis; Pruritus
  • PublicationOpen Access
    Dermatoscopic findings of pigmented purpuric dermatosis
    (2016-09-01) Su, Ozlem; OZKAYA, Dilek Biyik; Emiroglu, NAZAN; Cengiz, FATMA PELİN; Bahali, ANIL GÜLSEL; Yildiz, PELİN; DEMIRKESEN, Cuyan; Onsun, NAHİDE; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; CENGİZ, FATMA PELIN; BAHALI, ANIL GÜLSEL; YILDIZ, PELİN; ONSUN, NAHIDE
    ackground:: Pigmented purpuric dermatosis is a chronic skin disorder of unknown aetiology characterised by symmetrical petechial and pigmented macules, often confined to the lower limbs. The aetiology of pigmented purpuric dermatosis is unknown. Dermatoscopy is a non-invasive diagnostic technique that allows the visualisation of morphological features invisible to the naked eye; it combines a method that renders the corneal layer of the skin translucent with an optical system that magnifies the image projected onto the retina. Objectives:: The aim of this study is to investigate the dermatoscopic findings of pigmented purpuric dermatosis. Methods:: This study enrolled patients diagnosed histopathologically with pigmented purpuric dermatosis who had dermatoscopic records. We reviewed the dermatoscopic images of PPD patients who attended the outpatient clinic in the Istanbul Dermatovenereology Department at the Bezmialem Vakıf University Medical Faculty. Results:: Dermatoscopy showed: coppery-red pigmentation (97%, n = 31) in the background, a brown network (34%, n = 11), linear vessels (22%, n = 7), round to oval red dots, globules, and patches (69%, n = 22; 75%, n = 24; 34%, n = 11; respectively), brown globules (26%, n = 8) and dots (53%, n = 17), linear brown lines (22%, n = 7), and follicular openings (13%, n = 4). Conclusion:: To our knowledge, this is the first study to report the dermatoscopy of pigmented purpuric dermatosis. In our opinion, dermatoscopy can be useful in the diagnosis of pigmented purpuric dermatosis.
  • PublicationOpen Access
    Which dermatology patients attend to Dermatology Outpatient Clinics during the SARS-CoV-2 outbreak in Turkey and what happened to them?
    (2020-05-11T04:00:00Z) CENGİZ, Fatma Pelin; EMİROĞLU, Nazan; BAHALI, ANIL GÜLSEL; DİZMAN, DİDEM; TAŞLIDERE, NAZAN; MERT, Ömer; Akarslan, Tahsin Cagdas; Gunes, Begum; KÜÇÜK, Özlem Su; ONSUN, Nahide; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; DİZMAN, DİDEM; TAŞLIDERE, NAZAN; GÜNEŞ, BEGÜM; MERT, ÖMER; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
    Coronavirus disease, first emerged in Wuhan, rapidly spread all over the world since December 2019. There are concerns about elective dermatology appointments and its results. Herein, we aimed to find out which type of dermatologic patients attended to dermatology outpatient clinic. The patients visiting the clinics for elective dermatologic diseases between March 11 and 18, 2020, were included in this study. Their age, sex, diagnosis of disease, requirement for emergent intervention, and their medical records about COVID-19 were obtained. There were 390 patients attending to the dermatology outpatient clinic in this period. The most common disease was acne (N: 94, 24%), only 19% of patients need emergent interventions or dose adjustment. There were 40 (10%) patients over the age of 65. After their visits, five patients were diagnosed as COVID-19 in 2weeks. Dermatologic examinations may be a vector for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission since being closed to the patient. Five of our patients were diagnosed as COVID-19 after their elective visit to hospital. Since the asymptomatic course of some young patients, most of our patients were not screened for COVID-19. Our findings support the concerns of elective physician examinations.
  • PublicationOpen Access
    Evaluation of mean platelet volume in localized scleroderma
    (2017-09-01) Bahali, ANIL GÜLSEL; Su, Ozlem; Emiroglu, NAZAN; Cengiz, FATMA PELİN; Kaya, MEHMET ONUR; Onsun, NAHİDE; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; KAYA, MEHMET ONUR; ONSUN, NAHIDE
    Abstract: Background: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation. Following activation, platelets rapidly release numerous mediators and cytokines, which contribute to inflammation. Objectives: To evaluate whether there was any relation between localized scleroderma and platelet parameters. Methods: Forty-one patients with localized scleroderma were enrolled in the study. The control group consisted of 30 healthy subjects. Results: The mean platelet volume level in the patient group was 9.9 ± 1.3 fl and in the control group was 7.6 ± 1.1 fl. This difference was statistically significant (p< 0.001). The plateletcrit values are minimally higher in the patient group as compared to the control group. It was statistically significant (p<0.001). There was no significant difference in the platelet counts between the two groups (p= 0.560) In the patient group, there was no significant relation between the mean platelet volume levels and clinical signs of disease (p=0.09). However, plateletcrit values are higher in generalized than localized forms of disease (p=0.01). Study Limitations: The limited number of patients and the retrospective nature of the study were our limitations. Conclusions: This study suggests that platelets might play a role in the pathogenesis of scleroderma. Platelet parameters may be used as markers for evaluating disease severity and inflammatory processes. Thus, there is a need for more detailed and prospective studies. Keywords: Blood platelets; Scleroderma, localized; Transforming growth factor beta
  • PublicationOpen Access
    Effectiveness of the Capparis spinosa Treatment in Vitiligo
    (2018-02-01T00:00:00Z) EMİROĞLU, NAZAN; CENGİZ, FATMA PELİN; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
  • PublicationOpen Access
    The relationship between body mass index, waist circumference and psoriatic arthritis in the Turkish population
    (2016-01-01) OZKAYA, Dilek Biyik; Onsun, NAHİDE; Su, Ozlem; Bahali, ANIL GÜLSEL; Dizman, DİDEM; Rezvani, AYLİN; Uysal, Omer; ONSUN, NAHIDE; SU KÜÇÜK, ÖZLEM; BAHALI, ANIL GÜLSEL; DİZMAN, DİDEM; REZVANİ, AYLİN; UYSAL, ÖMER
    Introduction: Psoriasis is a chronic, immune-mediated inflammatory disease predominantly affecting the skin, with a complex aetiology. Recently it has been suggested that the chronic inflammation of psoriasis may cause metabolic and vascular disorders. The relationship between obesity and psoriatic arthritis (PsA) is not clear, and there are insufficient prospective studies addressing this subject. Aim: To investigate the relationship between psoriatic arthritis, severity of psoriasis and obesity in the Turkish population. Material and methods: Patient data from psoriasis outpatient clinics from February 2007 to July 2013 were reviewed retrospectively using the Psoriasis-Turkey (PSR-TR) registration system. Patients' age, onset age, body mass index (BMI), waist circumference, psoriasis area and severity index (PASI), and arthritis information were reviewed. In the outpatient clinics, patients who had joint pain consulted rheumatology clinics. The CASPAR criteria were used for the diagnosis of arthritis. Results: A total of 443 males and 495 females enrolled in this study. The mean age of females was 43.9 years (18-93 years) and the mean age of males was 44.6 years (18-89 years). A total of 231 (25%) patients had psoriatic arthritis. Investigation of the relationship between PASI, BMI, waist circumference (WC) and arthritis revealed a statistically significant relationship between each variable. Conclusions: In this study we observed a relationship between PsA and high BMI, high WC and high PASI. Psoriatic arthritis is a chronic inflammatory disorder and a chronic inflammatory state induced by adiposity may lead to PsA.
  • PublicationOpen Access
    Evaluation of Mean Platelet Volume in Patients with Pigmented Purpuric Dermatosis
    (2017-01-01) Su, Ozlem; Bahali, ANIL GÜLSEL; OZKAYA, Dilek Biyik; Cengiz, FATMA PELİN; Emiroglu, NAZAN; Kaya, MEHMET ONUR; Onsun, NAHİDE; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; KAYA, MEHMET ONUR; ONSUN, NAHIDE
    Objective: Pigmented purpuric dermatosis (PPD) is a chronic skin disease characterized by petechial and pigmentary macules. The etiology of the disease remains unknown. Mean platelet volume (MPV) is a marker of platelet (PLT) function and activation. PLTs play important roles in inflammation and innate and adaptive immunity in addition to their roles in hemostasis and thrombosis. In this study, we investigated the possible association between MPV and PPD.
  • PublicationOpen Access
    Prognostic factors of patients with mycosis fungoides
    (2020-01-01T00:00:00Z) BAHALI, ANIL GÜLSEL; Su, Özlem Su; CENGİZ, Fatma Pelin; EMİROĞLU, Nazan; Ozkaya, Dilek Biyik; ONSUN, Nahide; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; ONSUN, NAHIDE
    Introduction: Mycosis fungoides (MF) is the most common type of primary cutaneous T-cell lymphoma. Prognostic factors may help to evaluate the course of the disease and may also be useful in selecting appropriate treatment plans for patients.
  • PublicationOpen Access
    Role of Helicobacter pylori in Rosacea
    (2018-01-01T00:00:00Z) EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
    Objective: Rosacea is a chronic, inflammatory skin disease. The etiology is not known exactly, and natural immunity, impaired dermal matrix, vasodilation, and fibrogenesis may play a role in the pathogenesis of rosacea. Many studies investigated the relationship between rosacea and Helicobacter pylori (HP) but the results were contradictory. Methods: Patients were retrospectively identified from those treated by the Department of Dermatology. A total of 47 rosacea patients and 27 healthy controls were included in the study. Helicobacter pylori (Hp Ag), Helicobacter pylori immunoglobulin A (Hp IgA), and Helicobacter pylori immunoglobulin G (Hp IgG) were investigated and statistically compared in groups. Results: There was statistically no difference between the groups in terms of Hp Ag positivity (p=0.871), Hp IgA positivity (p=0.806), and Hp IgG positivity (p=0.330). Conclusions: Although we did not observe any difference between groups, we were unable to evaluate whether there is a reduction in symptoms with HP eradication. Further studies are needed to clarify the relation between HP infections with rosacea and other dermatological disorders.