Person: BEKTAŞOĞLU, HÜSEYİN KAZIM
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Publication Metadata only COMPARISON OF LIFT AND FISTULOTOMY IN TREATMENT OF INTERSPHINCTERIC AND LOW TRANSSPHINCTERIC ANAL FISTULA: PROSPECTIVE RANDOMIZED STUDY.(2015-05-01T00:00:00Z) Yardimci, E.; Cipe, G.; Hasbahceci, M.; Aysan, E.; Bektasoglu, HÜSEYİN KAZIM; Idiz, U.; Muslumanoglu, M.; BEKTAŞOĞLU, HÜSEYİN KAZIMPublication Metadata only Laparoscopic sleeve gastrectomy in management of weight regain after failed laparoscopic plication.(2013-01-01T00:00:00Z) Coskun, H; Cipe, G; Bozkurt, S; Bektasoglu, HÜSEYİN KAZIM; Hasbahceci, M; Muslumanoglu, M; BEKTAŞOĞLU, HÜSEYİN KAZIMPublication Open Access Comparison of Laparoscopic and Conventional Cystotomy/Partial Cystectomy in Treatment of Liver Hydatidosis(2019-01-01) Bektasoglu, HÜSEYİN KAZIM; HASBAHCECI, Mustafa; Taşçı, Yunus; Aydogdu, Ibrahim; MALYA, FATMA ÜMİT; Kunduz, ENVER; Dolay, KEMAL; BEKTAŞOĞLU, HÜSEYİN KAZIM; AYDOĞDU, İBRAHİM; MALYA, FATMA ÜMİT; KUNDUZ, ENVER; DOLAY, KEMALIntroduction. Hydatidosis is a zoonotic infection and treatment is mandatory to avoid complications. Surgery remains the frst choice in the treatment especially for CE2-CE3b cysts. Open or laparoscopic approaches are available. However, comparative studies are limited. Materials and Methods. Data of patients who underwent cystotomy/partial cystectomy for liver hydatidosis between January 2012 and September 2016 (n=77) were evaluated retrospectively. Recurrent cases and the patients with previous hepatobiliary surgery were excluded. 23 patients were operated upon laparoscopically and named as Group 1. 48 patients operated conventionally named as Group 2. Demographics, cyst characteristics, operative time, length of hospital stay, recurrences, and surgery related complications were evaluated. Results. Groups were similar in terms of demographics, cyst characteristics, and operative time. Te length of hospital stay was 3.4 days in Group 1 and 4.7 days in Group 2 (p=0,007). Te mean follow-up period was 17.8 months and 21.7 months, respectively (p=0.170). Overall complication rates were similar in two groups (p=0.764). Tree conversion cases occurred (13%). One mortality was seen in Group 2. Four recurrences occurred in each group (17% versus 8.3%, respectively) (p=0.258). Conclusions. Laparoscopy is a safe and feasible approach for surgical treatment of liver hydatidosis. Recurrence may be prevented by selection of appropriate cases in which exposure of cysts does not pose an intraoperative difcultyPublication Open Access Metachronous metastatic paraganglioma in jejunum as a rare entity: A case report(2015-03-01) Bektasoglu, HÜSEYİN KAZIM; CIPE, Gokhan; YARDIMCI, ERKAN; Arici, DİLEK SEMA; HASBAHCECI, Mustafa; KARATEPE, Oguzhan; MUSLUMANOGLU, Mahmut; BEKTAŞOĞLU, HÜSEYİN KAZIM; YARDIMCI, ERKAN; ARICI, DILEK SEMAPheochromocytomas and paragangliomas are neuroendocrine tumors that arise from chromaffin cells of adrenal medulla and extra-adrenal paraganglia, respectively. The recurrence of these neuroendocrine tumors as a jejunal mass causing obstruction in the small intestine is an exceptional entity. The present study reports the case of a 70-year-old male who presented to the Emergency Department of Bezmialem Vakif University Hospital with abdominal pain and vomiting. The patient possessed a history of left nephrectomy due to malignant pheochromocytoma that had invaded into the left kidney eight months prior to presentation. Bowel obstruction was diagnosed and the patient underwent a laparoscopic procedure. Partial resection of the jejunum was performed and immunohistochemical studies revealed the lesion to be malignant paraganglioma. The majority of paragangliomas are chemo- and radioresistant. Surgical excision remains the primary treatment. Metachronous paraganglioma arising from the small intestine is an extremely rare entity and may be a relevant consideration in patients presenting with bowel obstruction.Publication Open Access Transvaginal Small Bowel Evisceration following Abdominoperineal Resection(2018-01-01) Kunduz, ENVER; Bektasoglu, HÜSEYİN KAZIM; Yigman, SAMET; Akbulut, HÜSEYİN; KUNDUZ, ENVER; BEKTAŞOĞLU, HÜSEYİN KAZIM; YIĞMAN, SAMET; AKBULUT, HÜSEYİNAbdominoperineal resection (APR) is one of the surgical techniques performed for the distal rectal cancer. The perineal herniation is one of the complications of APR surgery. In this report, we aim to demonstrate a rare case of small bowel evisceration and strangulation secondary to the transvaginal herniation evolved in the late stage after perineal hernia repair following laparoscopic APR.Publication Metadata only Prospective multi-center study of surgeon-s assessment of the gallbladder compared to histopathological examination to detect incidental malignancy.(2019-08-01T00:00:00Z) Firat, YD; Idiz, UO; Cakir, C; Yardimci, ERKAN; Yazici, P; Bektasoglu, HÜSEYİN KAZIM; Bozkurt, E; Ucak, R; Gucin, ZÜHAL; Uresin, T; Hasbahceci, M; YARDIMCI, ERKAN; BEKTAŞOĞLU, HÜSEYİN KAZIM; GÜCİN, ZÜHALPublication Metadata only Midgut malrotation causing intermittent intestinal obstruction in a young adult.(2014-01-01T00:00:00Z) Bektasoglu, HÜSEYİN KAZIM; Idiz, UO; Hasbahceci, M; Yardimci, ERKAN; Firat, YD; Karatepe, O; Muslumanoglu, M; BEKTAŞOĞLU, HÜSEYİN KAZIM; YARDIMCI, ERKANPublication Open Access Analysis of Appendiceal Neoplasms on 3544 Appendectomy Specimens for Acute Appendicitis: Retrospective Cohort Study of a Single Institution(2018-06-27) Destek, Sebahattin; Bektasoglu, HÜSEYİN KAZIM; Unver, NURCAN; Aydogan, CEYHUN; Timocin, GİZEM; KUNDUZ, ENVER; BEKTAŞOĞLU, HÜSEYİN KAZIM; ÜNVER, NURCAN; AYDOĞAN, CEYHUN; TİMOÇİN, GİZEM; DESTEK, SABAHATTİNBACKGROUND Appendiceal neoplasms are rare and generally determined in appendectomy specimens for acute appendicitis. Depending on a tumor's histopathology and size, appendectomy or right hemicolectomy are the surgical treatment options. Adenocarcinomas, mucinous neoplasms, goblet cell carcinoids and neuroendocrine tumors are the types of the primary appendiceal neoplasm histopathology. In this study, we aimed to determine the incidence of appendiceal neoplasms in an acute appendicitis cohort. Also, histopathological distributions, demographic data, preoperative radiological diagnosis, and intraoperative findings were revealed for analysis, retrospectively. MATERIAL AND METHODS Between October 2011 and September 2017, 3554 appendectomies were performed for acute appendicitis in Bezmialem University Hospital, Istanbul Turkey. The medical records of these consecutive 3554 patients were evaluated retrospectively. After the histopathological analysis of the appendectomy specimens, a total of 28 patients were detected as having appendiceal neoplasm including appendiceal adenocarcinoma, low grade mucinous neoplasia, and appendiceal neuroendocrine tumors. RESULTS Appendiceal neoplasms were determined in 28 out of 3554 acute appendicitis patients with an incidence of 0.78%. According to the histopathological types, 3 of the cases (10.7%) were appendiceal adenocarcinoma, 8 of the cases (28.5%) were low grade mucinous neoplasia, and 17 of the cases (60.8%) were neuroendocrine tumors. The overall incidence of the appendiceal neuroendocrine tumors was 0.48%. CONCLUSIONS The information obtained from our study suggests that pathological examination of the specimen may not be necessary if there is no doubt according to preoperative radiological diagnosis and/or intraoperative findings of the surgeon.Publication Metadata only The weight and ghrelin changes of fecal microbiota transplantation in rats(2018-09-01T00:00:00Z) Idiz, Cemile; Bektasoglu, HÜSEYİN KAZIM; CELIKTEN, Mert; NAYCI, Ali Emre; OKMEN, Hasan; IDIZ, Ufuk Oguz; Demirci, Selami; AYSAN, Erhan; BEKTAŞOĞLU, HÜSEYİN KAZIMBackground: Fecal microbiota transplantation is a promising method to solve obesity. Our study-s aim was to investigate the changes of weight and ghrelin levels in obese rats receiving fecal microbiota transplantation from lean rats. Methodology: Twenty-one rats were divided into three equal groups: Group 1: Obese control group; group 2: Obese recipient group; and group 3: Lean donor group. Feces which was collected from donor group was transferred to the rats in recipient group, orally by gavage, 3 times every other day. The weight and ghrelin levels were measured from each rat at the beginning and end of the study. Results: There was statistically significant weight gain in donor group (p: 0.001), but there were no statistical significant weight chances was detected in control and recipient groups (p: 0.82, p: 0.12, respectively). There was an increase in donor and control groups, but a decrease was observed in the recipient group at ghrelin levels. However, there was no significant difference at ghrelin levels in any groups (p: 0.05, p: 0.2, p: 0.4, respectively). There was a significant relation in control group in weight and ghrelin changes (p: 0.007), but no significant relation was detected in either recipient or donor groups (p: 0.29, 0.53, respectively). Conclusion: Metabolism changes of obese rats were observed after fecal microbiota transplantation, and it was the only group that decreasing ghrelin levels.Publication Open Access Relationship between intestinal microbiota and colorectal cancer(2015-10-15T00:00:00Z) Cipe, Gokhan; Idiz, Ufuk Oguz; Firat, Deniz; Bektasoglu, HÜSEYİN KAZIM; BEKTAŞOĞLU, HÜSEYİN KAZIMThe human gastrointestinal tract hosts a complex and vast microbial community with up to 10(11) - 10(12) microorganisms colonizing the colon. The gut microbiota has a serious effect on homeostasis and pathogenesis through a number of mechanisms. In recent years, the relationship between the intestinal microbiota and sporadic colorectal cancer has attracted much scientific interest. Mechanisms underlying colonic carcinogenesis include the conversion of procarcinogenic diet-related factors to carcinogens and the stimulation of procarcinogenic signaling pathways in luminal epithelial cells. Understanding each of these mechanisms will facilitate future studies, leading to the development of novel strategies for the diagnosis, treatment, and prevention of colorectal cancer. In this review, we discuss the relationship between colorectal cancer and the intestinal microbiota.