Person: EREN, SABRİ BAKİ
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Publication Open Access Letter to the Editor regarding article by Hussein et al. doi:10.1007/s00405-014-3309-7(2015-10-01) Eren, SABRİ BAKİ; TUGRUL, Selahattin; OZUCER, Berke; Meric, Aysenur; Ozturan, ORHAN; EREN, SABRİ BAKİ; MERİÇ HAFIZ, AYŞENUR; ÖZTURAN, ORHANPublication Open Access Effect of Radiofrequency on DNA Damage and Oxidative Status in Patients with Turbinate Hypertrophy.(2019-11-01) Tugrul, S; Koçyiğit, A; Senturk, E; Doğan, Remzi; Eren, SB; Ozturan, ORHAN; Kesgin, S; ŞENTÜRK, EROL; TUĞRUL, SELAHATTİN; DOĞAN, REMZI; EREN, SABRİ BAKİ; ÖZTURAN, ORHAN; KOÇYİĞİT, ABDÜRRAHİMThe radiofrequency devices that are used generate radiofrequency in the frequency range of 1.5 and 2.5 MHz. This study aims to demonstrate whether systematic oxidative status and DNA are influenced in this frequency range. In study, 27 patients who received radiofrequency treatment on inferior turbinate as they were diagnosed with inferior turbinate hypertrophy. DNA damage was assessed by alkaline comet assay in peripheral lymphocyte cells. Plasma levels of total antioxidant status (TAS), total oxidative status (TOS) were determined by using an automated measurement method and oxidative stress index (OSI) was calculated (OSI was calculated as: OSI = (TOS/TAS) × 100). There were increased in the OSI and TOS values on days 1 and 15 as compared to the samples taken before the radiofrequency administration. Significant decreases were seen in TAS values on days 1 and 15. As for the DNA damage, no significant differences were found on day 15 compared to the preoperative values even though there was a statistically insignificant increase on day 1. Administration of radiofrequency radiation on inferior turbinates results in increased oxidative stress in the acute period and a decrease in the anti-oxidative system. Although this effect causes a slight increase in the DNA damage in the early post-operative period, the damage is restored to the pre-operative levels on day 15. Therefore, we believe that a more conservative approach should be selected for radiofrequency treatment instead of using it routinely.Publication Open Access Factors influencing the longevity and replacement frequency of Provox voice prostheses.(2015-11-01) OZKUL, MH; Meric, AYŞENUR; TUGRUL, SELHATTİN; EREN, SABRİ BAKİ; YENIGUN, A; YENİGÜN, ALPER; EREN, SABRİ BAKİ; TUĞRUL, SELAHATTİN; MERİÇ HAFIZ, AYŞENURINTRODUCTION This study aimed to assess the factors that influence the longevity and replacement frequency of Provox voice prostheses following their placement. METHODS The medical records of 27 patients who received Provox voice prostheses after total laryngectomy and attended follow-up regularly between 1998 and 2012 were retrospectively reviewed. The success rate of the Provox voice prostheses (i.e. whether speech was achieved), quality of speech achieved, number and type of complications encountered, frequency of prostheses replacement and reasons for prostheses replacements were evaluated. RESULTS All 27 patients were men and their mean age was 63.0 (range 43–78) years. The mean follow-up period was 60.3 (range 1–168) months. Fluent and understandable speech was achieved in 85.0% of the patients. The mean duration before prosthesis replacement had to be performed was 17.1 (range 1–36) months. The most frequent complication was fluid leakage through the prosthesis. There was a strong positive correlation of 77.1% between the longevity of prostheses and postoperative follow-up duration (r = 0.771; p < 0.01). CONCLUSION The voice prosthesis is a tool that can be delivered in a practical fashion and replaced easily with no serious complications. It is a means by which speech can be restored, with a high success rate, after total laryngectomy. In the present study, we found that postoperative follow-up duration was the most important factor influencing the longevity of the Provox voice prosthesis.Publication Open Access A randomised prospective trial of trans-septal suturing using a novel device versus nasal packing for septoplasty.(2010-06-01T00:00:00Z) KORKUT, AY; Teker, AYŞENUR; EREN, SABRİ BAKİ; GEDIKLI, O; ASKINER, O; MERİÇ HAFIZ, AYŞENUR; EREN, SABRİ BAKİBackground: Nasal packing or trans-septal sutures are used to prevent postoperative complications in septoplasty. Trans-septal suturing is not commonly used, since it takes time and is technically difficult with the available devices following septoplasty. Methods: This study included 64 patients who underwent septoplasty. Following septoplasty, the patients were divided into two groups: group I had trans-septal sutures placed using a novel device and group 2 had the nose packed with a tampon. The duration of surgery, postoperative symptoms and complications were compared. Results: All of the postoperative symptoms were significantly less in the group with trans-septal sutures. The mean duration of surgery was 34.9 minutes in the nasal packing group and 37.8 minutes in the trans-septal suture group, and the difference was significant (p = 0.026). No postoperative bleeding, submucoperichondrial haematomas, infections or abscesses occurred in any of the patients, whilst nasal perforation was observed in one patient in each group. Two (5.4%) patients in group I and one (3.7%) patient in group 2 had postoperative adhesions. Conclusions: We have developed a simple, inexpensive device for performing trans-septal suturing that is easy to use in the nasal cavity. We conclude that the use of continuous septal suturing with our device is an easy modification of the standard procedure, with only a small increase in operating time.Publication Open Access Are There Any Systemic Effects of the Intratympanic Administration of Dexamethasone?(2018-07-01T00:00:00Z) Senturk, Erol; Tugrul, Selahattin; Yildirim, Yavuz Selim; DOĞAN, Remzi; EREN, SABRİ BAKİ; ÖZTURAN, ORHAN; ŞENTÜRK, EROL; YILDIRIM, YAVUZ SELİM; DOĞAN, REMZI; EREN, SABRİ BAKİ; ÖZTURAN, ORHANObjective: Systemic absorption of steroids is reasonable because of the lipophilic nature of steroids and high vascularity of the middle ear mucosa. To date, however, of the clinical trials designed to investigate this subject, to the best of our knowledge, none has been based on objective methods. This study aims to demonstrate whether the intratympanic administration of dexamethasone has any systemic effects.Publication Open Access Isolated Traumatic Facial Palsy Based on Pinprick to the Tympanic Membrane(2015-08-01) TUGRUL, Selahattin; SENTURK, EROL; SEZEN GOKTAS, Seda; Eren, SABRİ BAKİ; Ozturan, ORHAN; ŞENTÜRK, EROL; EREN, SABRİ BAKİ; ÖZTURAN, ORHANTranstympanic penetrating trauma is one of the reasons of rarely seen peripheral facial paralysis. In this case, we observed the traumatic facial paralysis which was formed by the facial canal damage of the dehiscent tympanic segment of the facial nerve as a result of a knitting needle penetrating the tympanic membrane, which was not previously studied in the literature.