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REZVANİ, AYLİN

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AYLİN
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REZVANİ
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Now showing 1 - 10 of 13
  • PublicationOpen Access
    The HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis and Is Associated with Resistant Psoriasis in the Turkish Population
    (2019-01-01T00:00:00Z) ONSUN, NAHİDE; Pirmit, Serpil; Ozkaya, Dilek; Çelik, Şirin; Rezvani, Aylin; CENGİZ, Fatma Pelin; Kekik, Cigdem; ONSUN, NAHIDE; REZVANİ, AYLİN; CENGİZ, FATMA PELIN
    Background. Psoriasis is a multifactorial immune-mediated infammatory disease triggered by both genetic and environmental factors. Te strong association between psoriasis and HLA-C∗06 allele has been demonstrated in various races. Te HLAC∗12 allele is closely related to the HLA-C∗06 family of alleles and shares identical sequences. To the best of our knowledge, there is no information about the relationship between HLA-C∗12 and psoriasis in the Turkish population. Te present study aims to determine this relationship. Methods. Tis case control study involved 150 patients with plaque-type psoriasis and 145 age- and gender-matched healthy individuals. Severity of psoriasis was measured using the PASI scores of all patients and joint involvement was investigated with CASPAR criteria. HLA-C alleles were determined with a Tepnel-Lifecodes system. Results. HLA-C∗06, HLA-C∗12, and HLA-C∗04 alleles were most commonly observed in psoriasis patients. HLA-C∗06 and HLA-C∗12 were signifcantly more frequent in the psoriasis group. HLA-C∗06 was 4.11 times more common in psoriasis patients. An increase in PASI (Psoriasis Area Severity Index) scores was compatible with HLA-C∗12 positivity. A need for systemic treatment was highly noticeable in patients with the HLA-C∗12 allele. Conclusions. HLA-C∗12 was found as the second most frequent allele with psoriasis in Turkish population and was associated with severe psoriasis. Our study is limited as we could not investigate other potentially related alleles other than HLA-C alleles and risk factors increasing severity of psoriasis.
  • PublicationOpen Access
    Factors Influencing Subspecialty Training and Career Choices: A National Survey of Physical and Rehabilitation Medicine Residents
    (2019-03-01T00:00:00Z) TOLU, SENA; REZVANİ, AYLİN; Gurcan Atci, Aysel; ŞENDUR, ÖMER FARUK; Kuran, Banu; Ataman, Sebnem; Bodur, Hatice; Oncu Alptekin, Julide; ÇAPKIN, ERHAN; Dogan, Deniz; doi.org/10.5606/ArchRheumatol.2019.6742; TOLU, SENA; REZVANİ, AYLİN
    Objectives: This study aims to determine the preferences of physical and rehabilitation medicine (PRM) residents in Turkey for future career choices, subspecialty training plans, and practice location and to identify the factors that influence those preferences.
  • PublicationOpen Access
    Turkish League Against Rheumatism National Recommendations for the Management of Ankylosing Spondylitis
    (2011-01-01T00:00:00Z) Bodur, Hatice; Sivas, Filiz; Yilmaz, Ozlem; Ozgocmen, Salih; Gunaydin, Rezzan; Kaya, Taciser; Ataman, Sebnem; ALTAN İNCEOĞLU, LALE; ALTAY, ZÜHAL; Aydog, Ece; BİRTANE, MURAT; Borman, Pinar; Bugdayci, Derya Soy; BÜTÜN, BÜLENT; Cakirbay, Hasim; Duruoz, Tuncay; Gurer, Gulcan; Hepguler, Simin; Kamanli, Ayhan; Kuru, Omer; Kucukdeveci, Ayse; Nacir, Baris; Olmez, Nese; REZVANİ, AYLİN; Yanik, Burcu Corekci; REZVANİ, AYLİN
    Objectives: To develop Turkish League Against Rheumatism (TLAR) National Recommendations for the management of ankylosing spondylitis (AS). Materials and methods: A scientific committee of 25 experts consisting of six rheumatologists and 19 physical medicine and rehabilitation specialists was formed by TLAR. Recommendations were based on the 2006 ASsessment in Ankylosing Spondylitis International Working Group (ASAS)/European League Against Rheumatism (EULAR) recommendations and a systematic review of associated publications between January 2005 and September 2010. A Delphi process was used to develop the recommendations. Twelve major recommendations were constructed for the management of AS. Voting using a numerical rating scale assessed the strength of each recommendation. Results: The 12 recommendations include patient assessment, patient follow-up along with pharmacological and nonpharmacological methods. Some minor additions and changes have been made to the ASAS/EULAR recommendations. All of the recommendations had sufficient strength. Conclusion: National recommendations for the management of AS were developed based on scientific evidence and consensus expert opinion. These recommendations will be updated regularly in accordance with recent developments. Key words: Ankylosing spondylitis; national recommendations; treatment
  • PublicationOpen Access
    Axial Spondyloarthritis and Autosomal Dominant Polycystic Kidney Disease in Two Siblings: A Rare Cooccurrence.
    (2018-03-04) YURDAKUL, OZAN VOLKAN; TAMER, AF; Küçükakkaş, OKAN; REZVANI, AYLİN; YURDAKUL, OZAN VOLKAN; KÜÇÜKAKKAŞ, OKAN; REZVANİ, AYLİN
    Autosomal dominant polycystic kidney disease (ADPKD) is the most frequently occurring hereditary kidney disease, and axial spondyloarthritis (SpA) is one of the most frequently occurring rheumatic diseases. Treatment-related decisions for axial SpA may pose a challenge in case of renal involvement. -e authors describe two siblings with cooccurrence of these two diseases. -e association of these two diseases is not well known. Practitioners should monitor renal function in SpA patients and take treatment-related decisions regarding renal involvement. Antitumor necrosis factor-alpha (anti-TNF-α) agents may be used in case nonsteroidal anti-in
  • PublicationOpen Access
    Functional limitations due to foot involvement in spondyloarthritis.
    (2016-07-01) OZARAS, N; HAVAN, N; POYRAZ, E; Rezvanı, AYLİN; AYDıN, TEOMAN; REZVANİ, AYLİN; AYDIN, TEOMAN
    [Purpose] Spondyloarthritis is a major inflammatory disease followed-up in the rheumatology clinics, foot involvement in spodyloarthritis is common. The functional states of patients with spondyloarthritis are usually evaluated globally. The aim of this study was to assess the foot involvement-related functional limitations in patients with spondyloarthritis. [Subjects and Methods] Patients with ankylosing spondylitis and psoriatic arthritis with foot pain more than 4 weeks who underwent anteroposterior and lateral feet radiography were enrolled into the study. A “clinical findings score” was calculated by assigning 1 point for every finding of swelling, redness, and tenderness. C-reactive protein and erythrocyte sedimentation rate were used as serum markers for disease activity. Foot radiograms were evaluated using the spondyloarthropathy tarsal radiographic index and the foot-related functional state of patients was determined by the Turkish version of the Foot and Ankle Outcome Score. [Results] There were no relationships between Foot and Ankle Outcome Score subscales and clinical findings score, serum markers, or radiologic score. Pain and symptoms subscale scores were result positively correlated with activity of daily living, sport and recreation, and quality of life subscale scores. [Conclusion] Pain and symptoms are the main determinants of foot-related functional limitations in spondyloarthritis. Key words: Foot, Spondyloarthritis, Foot and Ankle Outcome Score
  • PublicationOpen Access
    Can ultrasound be an assessment tool for sagittal spine mobility and chest expansion in patients with ankylosing spondylitis?
    (2018-09-01T00:00:00Z) Yurdakul, OZAN VOLKAN; REZVANI, AYLİN; YURDAKUL, OZAN VOLKAN; REZVANİ, AYLİN
  • PublicationOpen Access
    Differential diagnosis of multiple vertebral compression: butterfly vertebrae.
    (2015-11-01) OZARAS, N; GUMUSSU, K; DEMIR, SE; Rezvani, AYLİN; REZVANİ, AYLİN
    [Purpose] A butterfly vertebra is a rare congenital anomaly resulting from a symmetric fusion defect. Only a few cases of butterfly vertebra have been described. This anomaly may be isolated or associated with Pfeiffer, Jarcho-Levins, Crouzon, or Alagille syndrome. [Subject and Methods] We herein describe a 38-year-old man who presented with neck and low back pain and was found to have butterfly vertebrae at the T9 and L3 levels. He also had Behçet’s disease and psoriasis. [Results] The patient’s symptoms improved with analgesics and physiotherapy. [Conclusion] To our knowledge, butterfly vertebrae at two levels have never been reported. Butterfly vertebrae may be confused with vertebral fractures in lateral radiographs, and awareness of this anomaly is important for a correct diagnosis
  • PublicationOpen Access
    Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with postmenopausal osteoporosis.
    (2016-08-01) AKARıRMAK, Ü; KOÇYIĞIT, H; ESKIYURT, N; ESMAEILZADEH, S; KURU, Ö; YALÇINKAYA, EY; PEKER, Ö; EKIM, AA; ÖZGIRGIN, N; ÇALıŞ, M; Rezvani, AYLİN; ÇEVIKOL, A; EYIGÖR, S; ŞENDUR, ÖF; İRDESEL, J; INSTRUCT, Study; REZVANİ, AYLİN
    Objective: In our study, we aimed to evaluate the influence of training on compliance and persistence with bisphosphonate treatment given on a weekly vs. monthly basis in postmenopausal osteoporosis patients. Methods: A total of 979 patients with postmenopausal osteoporosis (mean age: 63.2 ± 7.2 years) were included in this national, multicenter, prospective non-interventional observational cohort registry study. Patients were randomized into training (n ¼ 492, 50.3%, mean age: 63.4 ± 7.2 years) and control (n ¼ 487, 49.7%, mean age: 63.0 ± 7.1 years) groups. Patients in each intervention group were given weekly (44.9% and 44.6% for training and control subjects, respectively) or monthly (55.1% and 55.4%, respectively) bisphosphonate regimens. After the initial visit, patients were followed up at three-month intervals throughout 12 months of treatment for evaluation of persistence, compliance and adverse events. Results: On average, 79.4% of the patients were persistent with the treatment with a mean of 350.4 days of duration during the 12-month follow-up period. The mean compliance in the compliant and fully compliant group remained at an average of 86.6%. No significant difference was detected between the training and control groups in terms of compliance and persistence. Significantly longer persistence (360.0 ± 89.0 vs. 345.0 ± 108.0 days; p ¼ 0.035), higher percentage of persistent patients (83.4% vs. 74.2%; p ¼ 0.012) and higher compliance rates (88.8% vs. 83.3%; p ¼ 0.002) were noted in monthly regimen patients in comparison to those given weekly regimen. Conclusion: Our findings revealed remarkably high rates for persistence and compliance with bisphosphonate treatment in postmenopausal osteoporosis, with no impact of training on compliance and persistence rates. Longer persistence and better compliance rates were achieved with the monthly bisphosphonate regimen when compared to the weekly regimen.
  • PublicationOpen Access
    The relationship between body mass index, waist circumference and psoriatic arthritis in the Turkish population
    (2016-01-01) OZKAYA, Dilek Biyik; Onsun, NAHİDE; Su, Ozlem; Bahali, ANIL GÜLSEL; Dizman, DİDEM; Rezvani, AYLİN; Uysal, Omer; ONSUN, NAHIDE; SU KÜÇÜK, ÖZLEM; BAHALI, ANIL GÜLSEL; DİZMAN, DİDEM; REZVANİ, AYLİN; UYSAL, ÖMER
    Introduction: Psoriasis is a chronic, immune-mediated inflammatory disease predominantly affecting the skin, with a complex aetiology. Recently it has been suggested that the chronic inflammation of psoriasis may cause metabolic and vascular disorders. The relationship between obesity and psoriatic arthritis (PsA) is not clear, and there are insufficient prospective studies addressing this subject. Aim: To investigate the relationship between psoriatic arthritis, severity of psoriasis and obesity in the Turkish population. Material and methods: Patient data from psoriasis outpatient clinics from February 2007 to July 2013 were reviewed retrospectively using the Psoriasis-Turkey (PSR-TR) registration system. Patients' age, onset age, body mass index (BMI), waist circumference, psoriasis area and severity index (PASI), and arthritis information were reviewed. In the outpatient clinics, patients who had joint pain consulted rheumatology clinics. The CASPAR criteria were used for the diagnosis of arthritis. Results: A total of 443 males and 495 females enrolled in this study. The mean age of females was 43.9 years (18-93 years) and the mean age of males was 44.6 years (18-89 years). A total of 231 (25%) patients had psoriatic arthritis. Investigation of the relationship between PASI, BMI, waist circumference (WC) and arthritis revealed a statistically significant relationship between each variable. Conclusions: In this study we observed a relationship between PsA and high BMI, high WC and high PASI. Psoriatic arthritis is a chronic inflammatory disorder and a chronic inflammatory state induced by adiposity may lead to PsA.
  • PublicationOpen Access
    Reliability and validity of the Turkish version of the fibromyalgia rapid screening tool (FiRST).
    (2017-02-01) CELIKER, R; ALTAN, L; Rezvani, AYLİN; AKTAS, I; TASTEKIN, N; DURSUN, E; DURSUN, N; SARıKAYA, SİYAMİ; OZDOLAP, S; AKGUN, K; ZATERI, C; BIRTANE, M; REZVANİ, AYLİN; SARIKAYA, SİYAMİ
    [Purpose] An easy-to-use, psychometrically validated screening tool for fibromyalgia is needed. This study aims to evaluate the reliability and validity of the Turkish version of the Fibromyalgia Rapid Screening Tool by correlating it with 2013 American College of Rheumatology alternative diagnostic criteria and the Hospital Anxiety and Depression Scale. [Subjects and Methods] Subjects were 269 Physical Medicine and Rehabilitation clinic outpatients. Patients completed a questionnaire including the Fibromyalgia Rapid Screening Tool (twice), 2013 American College of Rheumatology alternative diagnostic criteria, and the Hospital Anxiety and Depression Scale. Scale reliability was examined by test-retest. The 2013 American College of Rheumatology alternative diagnostic criteria was used for comparison to determine criterion validity. The sensitivity, specificity, and positive and negative likelihood ratios were calculated according to 2013 American College of Rheumatology alternative diagnostic criteria. Logistic regression analysis was conducted to find the confounding effect of the Hospital Anxiety and Depression Scale on Fibromyalgia Rapid Screening Tool to distinguish patients with fibromyalgia syndrome. [Results] The Fibromyalgia Rapid Screening Tool was similar to the 2013 American College of Rheumatology alternative diagnostic criteria in defining patients with fibromyalgia syndrome. Fibromyalgia Rapid Screening Tool score was correlated with 2013 American College of Rheumatology alternative diagnostic criteria subscores. Each point increase in Fibromyalgia Rapid Screening Tool global score meant 10 times greater odds of experiencing fibromyalgia syndrome. [Conclusion] The Turkish version of the Fibromyalgia Rapid Screening Tool is reliable for identifying patients with fibromyalgia.