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UZUNER, SELÇUK

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SELÇUK
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Now showing 1 - 10 of 12
  • PublicationOpen Access
    Evaluation of 563 children with chronic cough accompanied by a new clinical algorithm
    (2015-10-06) GEDIK, Ahmet Hakan; BAHALI, Kayhan; KUCUKKOC, Mehmet; NURSOY, Mustafa; GOKCE, Selim; Cakir, ERKAN; Ozkaya, EMİN; Uzuner, SELÇUK; Erenberk, UFUK; Torun, EMEL; DEMIR, Aysegul Dogan; AKSOY, Fadlullah; ÇAKIR, ERKAN; TORUN, EMEL; ERENBERK, UFUK; UZUNER, SELÇUK; NURSOY, MUSTAFA ATİLLA; ÖZKAYA, EMİN; AKSOY, FADLULLAH
    Background: This study aims to evaluate the children with chronic cough and to analyze their etiological factors according to the age groups. Method: Five hundred sixty-three children with chronic cough were included. The last diagnosis were established and were also emphasized according to the age groups. Results: The mean age was 5.4 ± 3.8 years (2-months–17-years) and 52 % of them were male. The most common final diagnosis from all the participants were: asthma (24.9 %), asthma-like symptoms (19 %), protracted bacterial bronchitis (PBB) (11.9 %), and upper airway cough syndrome (9.1 %). However, psychogenic cough was the second most common diagnosis in the subjects over 6 years of age. Conclusion: Asthma and asthma-like symptoms were the most common diagnosis in children. Different age groups in children may have a different order of frequencies. Psychogenic cough should be thought of in the common causes especially in older children.
  • PublicationOpen Access
    Pulmonary Edema in the Acute Stage of Rheumatic Fever Treated with Double-Valve Replacement in a Pediatric Patient
    (2020-03-01T00:00:00Z) Yozgat, Yilmaz; Uzuner, Selcuk; YEŞİLBAŞ, OSMAN; Ogur, Mustafa; YAKUT, KAHRAMAN; Yozgat, Can Yilmaz; Temur, Hafize Otcu; AY, YASİN; YOZGAT, YILMAZ; UZUNER, SELÇUK; YAKUT, KAHRAMAN; AY, YASİN
    Cardiogenic pulmonary edema (CPE) is a rare clinical condition of acute rheumatic fever (ARF) in the early stage. Generally, CPE can be convalesced by steroid and anticongestive treatment. Herein, we describe a case of a 14-year-old boy with ARF presenting with bilateral pulmonary edema secondary to acute mitral and aortic insufficiency. In this case, the pulmonary edema of ARF was successfully managed by combined surgical replacements of both valves.
  • PublicationOpen Access
    Hematological indices for differential diagnosis of Beta thalassemia trait and iron deficiency anemia.
    (2014-01-01) OZGURHAN, G; DEMIR, AD; Uzuner, SELÇUK; NURSOY, MUSTAFA ATİLLA; TURKMEN, S; KACAN, A; VEHAPOĞLU TÜRKMEN, AYSEL; UZUNER, SELÇUK; NURSOY, MUSTAFA ATİLLA
    Background. The two most frequent types of microcytic anemia are beta thalassemia trait (𝛽-TT) and iron deficiency anemia (IDA). We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis and 𝛽-TT in the same patient groups. Methods. A total of 290 carefully selected children aged 1.1–16 years were evaluated. We calculated 12 discrimination indices in all patients with hemoglobin (Hb) values of 8.7–11.4 g/dL. None of the subjects had a combined case of IDA and 𝛽-TT. All children with IDA received oral iron for 16 weeks, and HbA2 screening was performed after iron therapy. The patient groups were evaluated according to red blood cell (RBC) count; red blood distribution width index; the Mentzer, Shine and Lal, England and Fraser, Srivastava and Bevington, Green and King, Ricerca, Sirdah, and Ehsani indices; mean density of hemoglobin/liter of blood; and mean cell density of hemoglobin. Results. The Mentzer index was the most reliable index, as it had the highest sensitivity (98.7%), specificity (82.3%), and Youden’s index (81%) for detecting 𝛽-TT; this was followed by the Ehsani index (94.8%, 73.5%, and 68.3%, resp.) and RBC count (94.8%, 70.5%, and 65.3%). Conclusion.The Mentzer index provided the highest reliabilities for differentiating 𝛽-TT from IDA.
  • PublicationOpen Access
    Subdural empyema, brain abscess, and superior sagittal sinus venous thrombosis secondary to Streptococcus anginosus
    (2021-01-01T00:00:00Z) YEŞİLBAŞ, Osman; YOZGAT, Can Yılmaz; Tahaoglu, Irmak; BURSAL DURAMAZ, BURCU; TÜREL, Özden; TEKİN, NUR; UZUNER, SELÇUK; Abdallah, Anas; YEŞİLBAŞ, OSMAN; YOZGAT, YILMAZ; BURSAL DURAMAZ, BURCU; TÜREL, ÖZDEN; TEKİN, NUR; UZUNER, SELÇUK
    Streptococcus anginosus can be frequently isolated from brain abscesses, but is a rare cause of the liver, lung, and deep tissue abscesses. In this report, we present a patient with subdural empyema, brain abscess, and superior sagittal cerebral venous thrombosis as complications of rhinosinusitis whose purulent empyema sample yielded S. anginosus. A 13-year-old female patient was referred to our pediatric intensive care unit with altered mental status, aphasia, and behavioral change. On a brain computed tomography scan, subdural empyema extending from the left frontal sinus to the frontal interhemispheric area and left hemispheric dura was detected. Intravenous ceftriaxone, vancomycin, and metronidazole treatments were started. Subdural empyema was surgically drained. Postoperative brain magnetic resonance venography imaging showed superior sagittal sinus thrombosis. Cultures obtained from purulent empyema sample revealed S. anginosus. On the third day of hospitalization, a brain computed tomography scan showed brain edema, especially in the left hemisphere and significantly increased subdural empyema that had been previously drained. She was reoperated and decompressive craniectomy was performed. On the fifth day, partial epileptic seizures occurred. Brain magnetic resonance imaging showed a brain abscess on the interhemispheric area. The magnetic resonance imaging findings of abscess formation improved on 30th day and she was discharged on the 45th day after the completion of antibiotic therapy.
  • PublicationOpen Access
    The relationship between severity of disease and vitamin D levels in children with atopic dermatitis
    (2017-01-01) Su, Ozlem; BEHALI, Anil Gulsel; DEMIR, Aysegul Dogan; OZKAYA, Dilek Biyik; Uzuner, SELÇUK; Dizman, DİDEM; Onsun, NAHİDE; SU KÜÇÜK, ÖZLEM; UZUNER, SELÇUK; DİZMAN, DİDEM; ONSUN, NAHIDE
    Introduction: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disorder. Vitamin D is a liposoluble vitamin synthesized mainly in the skin. Vitamin D has several effects on the skin. Aim: To assess the serum level of vitamin D in children with AD and determine its relation to AD severity. Material and methods: Sixty patients with AD were enrolled in the study. We evaluated disease severity using the SCORing Atopic Dermatitis (SCORAD) index. The control group consisted of 37 healthy subjects. Results: The mean serum concentration of 25(OH)D3 in patients with AD was not statistically different from control subjects (p = 0.065). The vitamin D level was significantly lower in moderate and severe AD compared with mild AD, and this difference was statistically significant (p = 0.001 and p = 0.004). Vitamin D showed a negative correlation with serum total IgE levels (p = 0.007). There was no significant correlation between total IgE levels and SCORAD scores (p = 0.089). Conclusions: This study suggests that a low serum vitamin D level is inversely associated with severity of AD in children. Vitamin D has not been included in the routine treatment of AD because of the conflicting results of various studies. Thus, there is a need for more detailed and prospective studies.
  • PublicationOpen Access
    Proper Interventions in a Newborn with Cerebro-Costo-Mandibular Syndrome
    (2018-01-01T00:00:00Z) Tanyeri Bayraktar, Bilge; Bayraktar, Suleyman; Karacanoglu, Dilek; ARALAŞMAK, Ayşe; UZUNER, SELÇUK; ARALAŞMAK, AYŞE; UZUNER, SELÇUK
    Cerebro-costo-mandibular syndrome is characterized by severe micrognathia with glossoptosis, short to cleft soft palate, bell-shaped small thorax with gaps between the posterior ossified rib and anterior cartilaginous rib and postnatal growth and mental deficiency. We present the clinical course and the early aggressive treatment of a newborn diagnosed as cerebro-costo-mandibular syndrome. The management of the patients with this syndrome is important over the morbidity and mortality. Most babies died due to respiratory distress. Although brain anomalies are uncommon in cerebro-costo-mandibular syndrome, hypoxia may cause neurodevelopmental disorders. In this case report, we emphasize the importance of proper ventilation and feeding in patients with cerebro-costo-mandibular syndrome to maintain normal development. Multidisciplinary approach is essential in monitoring of these patients.
  • PublicationOpen Access
    A 13-Year-Old Boy Who Has Kawasaki Disease Shock Syndrome Presents with Parotitis
    (2020-03-01T00:00:00Z) YOZGAT, Yılmaz; UZUNER, SELÇUK; Demir, Aysegul Dogan; OĞUR, MUSTAFA; Yozgat, Can Yilmaz; TÜREL, Özden; YOZGAT, YILMAZ; UZUNER, SELÇUK; OĞUR, MUSTAFA; TÜREL, ÖZDEN
    We report a 13-year-old boy who (initially) had symptoms of toxic shock-like syndrome and mumps. Then, the patient was hospitalized in the pediatric intensive care unit (PICU) because of his ongoing hemodynamic instability (low blood pressure of 70/30 mm Hg and capillary refill time of > 4 seconds). During his stay in the PICU, the patient was treated with fluid resuscitation and vasoactive infusion and at the same time was diagnosed with Kawasaki disease shock syndrome (KDSS), when giant right coronary artery aneurysms were detected on echocardiographic examination. This case illustrates the risk of KDSS in patient who carries both parotitis and toxic shock-like syndrome. The clinicians should be cautious about detecting any types of coronary artery aneurysms in such patients. This is the first case of KDSS associated with parotitis reported in the literature.
  • PublicationOpen Access
    Dermatological Manifestation of Pediatrics Multisystem Inflammatory Syndrome Associated with COVID-19 in a 3-Year-Old Girl.
    (2020-06-04T00:00:00Z) Yozgat, CY; Uzuner, S; Duramaz, BB; Yozgat, Yılmaz; Erenberk, U; Iscan, A; Turel, O; UZUNER, SELÇUK; YOZGAT, YILMAZ; ERENBERK, UFUK; TÜREL, ÖZDEN
  • PublicationOpen Access
    Osteocalcin, Cortisol Levels, and Bone Mineral Density in Prepubertal Children with Asthma Treated with Long-Term Fluticasone Propionate
    (2012-01-01) Ozkaya, EMİN; NURSOY, Mustafa A.; Erenberk, UFUK; Cakir, ERKAN; ÖZKAYA, EMİN; NURSOY, MUSTAFA ATİLLA; UZUNER, SELÇUK; ERENBERK, UFUK; ÇAKIR, ERKAN
    Aims: The objective of this study is to determine the effects of the long-term treatment with inhaled fluticasone propionate on osteocalcin, cortisol levels, and bone mineral status in children with asthma. Methods: This cross-sectional study examined 230 prepubertal children with asthma (aged 6–11) who had intermittently used inhaled fluticasone propionate for at least 5 years at a mean daily dose of 200 μg (range: 200-350 μg). Serum osteocalcin, cortisol, and bone mineral density (BMD) of the lumbar spine were obtained from each participant. The control group consisted of gender- and age-matched children (n = 170) who were newly diagnosed with asthma and who were not being treated with corticosteroid. Results: The average age (± SEM) was 8.9 ± 0.7 years, their mean (± SEM) daily steroid dose was 180.3 ± 55.0 μg, with 236.5 ± 17.2 g total steroid use during treatment. Between the study and the control groups, no significant differences were observed in cortisol, osteocalcin levels, and BMD (p > 0.05). Conclusion: Long-term treatment with inhaled fluticasone propionate (100 μg twice daily) revealed no negative effects on serum osteocalcin, cortisol levels, and BMD in children with asthma.
  • PublicationOpen Access
    Evaluation of diagnostic components and management of childhood pulmonary tuberculosis: a prospective study from Istanbul, Turkey.
    (2022-01-31T00:00:00Z) Dogan Demir, Aysegul; Kut, Arif; Ozaydin, Erhan; Cakir, Fatma Betul; Nursoy, Mustafa; Ustabas Kahraman, Feyza; Erenberk, Ufuk; Uzuner, Selcuk; Collak, Abdulhamit; Cakin, Zeynep Ebru; Cakir, Erkan; ÇAKIR, FATMA BETÜL; USTABAŞ KAHRAMAN, FEYZA; ERENBERK, UFUK; UZUNER, SELÇUK; ÇAKIR, ERKAN
    Introduction: The diagnosis of childhood tuberculosis is difficult and most of the patients are diagnosed clinically. The objective of this study is to reveal the diagnostic and therapeutic components of childhood pulmonary tuberculosis and to analyze the changes that occurred in our country over the years. Methodology: All patients diagnosed with tuberculosis between 2006 and 2016 were included. Demographic characteristics, diagnostic and treatment outcomes were recorded and patients were followed up prospectively. Results: A total of 492 patients were included in the study. 97% had Bacillus Calmette-Guerin vaccine, 36% were diagnosed with microbiologically-confirmed tuberculosis and 64% were diagnosed with clinically-proven tuberculosis. 94% of the patients had symptoms consistent with tuberculosis, all patients had radiologic findings, 74% had a history of tuberculosis contact and 63% had tuberculin skin test positivity. The diagnoses included primary tuberculosis in 62%, secondary tuberculosis in 21%, progressive primary tuberculosis in 13% and miliary tuberculosis in 4%. 48% of the patients received a treatment regimen containing three drugs as the initial treatment, and drug-related side effects developed in 12%. Isoniazid resistance was detected in 13% of the patients and rifampicin resistance was detected in 8%. None of the patients died due to tuberculosis. In the last 50 years in Turkey, the rates of Bacillus Calmette-Guerin vaccination and diagnosis of tuberculosis cases have increased and the mortality rates have decreased over the years. Conclusions: Our study is one of the few prospective studies and revealed the differences between the recent data and the past 50 years in childhood tuberculosis in Turkey.