Person:
SÜMBÜL, BİLGE

Loading...
Profile Picture
Status
Organizational Units
Organizational Unit
Job Title
First Name
BİLGE
Last Name
SÜMBÜL
Name
Email Address
Birth Date

Search Results

Now showing 1 - 10 of 12
  • PublicationMetadata only
    Çocukluk çagı kistik fibrosiz dısı bronsektazi hastalarının anaerobik ve aerobik yükü
    (2014-04-10T00:00:00Z) Çakır, Erkan; Daşkaya, Hayrettin; Sümbül, Bilge; ÇAKIR, ERKAN; DAŞKAYA, HAYRETTİN; SÜMBÜL, BİLGE
  • PublicationMetadata only
    Karında Şişlik ile Saptanan Pott Apsesi Olgusu
    (2022-05-25T00:00:00Z) Karakuş, Hatice Dilara; Akkoyunlu, Yasemin; Sümbül, Bilge; Altıntaş, Fazılhan; Aslan, Turan; KARAKUŞ, HATİCE DİLARA; AKKOYUNLU, YASEMİN; SÜMBÜL, BİLGE; ALTINTAŞ, FAZILHAN; ASLAN, TURAN
  • PublicationMetadata only
    Anaerobic and aerobic bacterial load of childhood non-cystic fibrosis bronchiectasis
    (2014-09-07T00:00:00Z) Iraz, Meryem; Çakır, Erkan; Gedik, Ahmet Hakan; Daşkaya, Hayrettin; Sümbül, Bilge; Keskin, N; Umutoğlu, Tarık; ÇAKIR, ERKAN; DAŞKAYA, HAYRETTİN; SÜMBÜL, BİLGE
  • PublicationOpen Access
    Usefulness of oxidative stress marker evaluation at admission to the intensive care unit in patients with COVID-19
    (2021-07-01T00:00:00Z) Daşkaya, Hayrettin; Yılmaz, Sinan; Uysal, Harun; Sümbül, Bilge; Karaaslan, Kazım; DAŞKAYA, HAYRETTİN; YILMAZ, SİNAN; UYSAL, HARUN; ÇALIM, MUHITTIN; SÜMBÜL, BİLGE; YURTSEVER, İSMAİL; KARAASLAN, KAZıM
    Objective:Two critical processes in the coronavirus disease 2019 (COVID-19) pandemic involve assessing patients- intensive care needs and predicting disease progression during patients- intensive care unit (ICU) stay. We aimed to evaluate oxidative stress marker status at ICU admission and ICU discharge status in patients with COVID-19.Methods:We included patients in a tertiary referral center ICU during June-December 2020. Scores of Acute Physiology and Chronic Health Evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA), and clinical severity, radiologic scores, and healthy discharge status were noted. We collected peripheral blood samples at ICU admission to evaluate total antioxidants, total oxidants, catalase, and myeloperoxidase levels.Results:Thirty-one (24 male, 7 female) patients were included. At ICU admission, patients- mean APACHE II score at ICU admission was 17.61 ± 8.9; the mean SOFA score was 6.29 ± 3.16. There was no significant relationship between clinical severity and oxidative stress (OS) markers nor between radiological imaging and COVID-19 data classification and OS levels. Differences in OS levels between patients with healthy and exitus discharge status were not significant.Conclusions:We found no significant relationship between oxidative stress marker status in patients with COVID-19 at ICU admission and patients- ICU discharge status.
  • PublicationMetadata only
    Covid-19-un akut böbrek hasar belirteçleri uzerine etkisi
    (2022-05-25T00:00:00Z) Akkoyunlu, Yasemin; Koçyiğit, Abdürrahim; Elçioğlu, Ömer Celal; Güler, Eray Metin; Sümbül, Bilge; Okay, Gülay; Durdu, Bülent; Bolukçu, Sibel; Kazancıoğlu, Rümeyza; Aslan, Turan; AKKOYUNLU, YASEMİN; KOÇYİĞİT, ABDÜRRAHİM; ELÇİOĞLU, ÖMER CELAL; SÜMBÜL, BİLGE; OKAY, GÜLAY; DURDU, BÜLENT; KAZANCIOĞLU, RÜMEYZA; ASLAN, TURAN
  • PublicationMetadata only
    Efficacy of Tocilizumab in Patients with a Moderate and Severe COVID-19: A Retrospective Single Center Cohort Study
    (2021-11-01T00:00:00Z) Karakuş, Hatice Dilara; Okay, Gülay; Akkoyunlu, Yasemin; Sümbül, Bilge; Durdu, Bülent; Meriç Koç, Meliha; Aslan, Turan; KARAKUŞ, HATİCE DİLARA; OKAY, GÜLAY; AKKOYUNLU, YASEMİN; SÜMBÜL, BİLGE; DURDU, BÜLENT; MERİÇ KOÇ, MELİHA; ASLAN, TURAN
  • PublicationMetadata only
    Kistik fibrozis dısı bronsektazili çocuk hastaların bronkoalveolar lavaj sıvılarında cathelicidin (LL37) ve human beta 2 defensin düzeyleri
    (2015-04-02T00:00:00Z) Gedik, Ahmet Hakan; Çakır, Erkan; Sümbül, Bilge; Daşkaya, Hayrettin; ÇAKIR, ERKAN; SÜMBÜL, BİLGE; DAŞKAYA, HAYRETTİN
  • PublicationOpen Access
    The relationship of Serum Histone H3.3 and H4 with chronic Hepatitis B
    (2020-09-01T00:00:00Z) Sümbül, Bilge; Şentürk, Hakan; Köker, İbrahim Hakkı; Koçhan, Koray; İnce, Ali Tüzün; Biberci Keskin, Elmas; İNCE, ALİ TÜZÜN; BİBERCİ KESKİN, ELMAS; SÜMBÜL, BİLGE; KOÇHAN, KORAY; KÖKER, İBRAHİM HAKKI; ŞENTÜRK, HAKAN
    Objective: To determine the role of serum histone H3.3 and H4 in patients with chronic hepatitis B to explore any relationship between the two.Methods: The prospective controlled clinical pilot study was conducted in the Gastroenterology Clinic of Bezmialem Vakif University, Istanbul, Turkey, from January to October 2017, and comprised biopsy-proven patients with chronic hepatitis B and healthy controls. Demographics, hepatitis B virus deoxyribonucleic acid quantity, hepatitis B e-antigen, aspartate aminotransferase, alanine transaminase, international normalized ratio, total/direct bilirubin, albumin and thrombocyte counts as well as histological activity index and fibrosis scores were noted. Data was analysed using SPSS 22.Results: Of the 140 subjects, 70(50%) each were cases and controls. The overall mean age of the sample was 43.38±15.07 years (range: 18-70 years). There was positive correlation of histone H3.3 with hepatitis B virus deoxyribonucleic acid, aspartate aminotransferase, alanine transaminase and international normalized ratio levels. Histone H4 levels only correlated with hepatitis B virus deoxyribonucleic acid and international normalized ratio. Hepatitis B e-antigen positivity was present in 14(20%) of the cases.Conclusion: Histone H3.3 levels appeared to be associated with pathophysiological changes in chronic hepatitis B patients, suggesting that future treatments should target H3.3.Keywords: Histone H3.3, Histone H4, Extracellular histone, Chronic Hepatitis B, HBV.(JPMA 70: 1596; 2020)DOI:https://doi.org/10.5455/JPMA.19365
  • PublicationMetadata only
    Actinomyces Odontolyticus Enfeksiyonlarına 2 Olgu ile Bakış
    (2021-05-20T00:00:00Z) Karakuş, Hatice Dilara; Akkoyunlu, Yasemin; Uslu, Ayşe Betül; Ekşi, Çağla; Sümbül, Bilge; Meriç Koç, Meliha; KARAKUŞ, HATİCE DİLARA; AKKOYUNLU, YASEMİN; USLU, AYŞE BETÜL; EKŞİ, ÇAĞLA; SÜMBÜL, BİLGE; MERİÇ KOÇ, MELİHA
  • PublicationMetadata only
    The Effects of Polypharmacy, Nutritional and Functional Status on the Progression of COVID-19 in Older Adults
    (2021-08-01T00:00:00Z) Ogun, Hamza; Akkoyunlu, Yasemin; Durdu, Bülent; Okyaltırık, Fatmanur; Kazancıoğlu, Rümeyza; Meriç Koç, Meliha; Gülen, Bedia; Sümbül, Bilge; Okay, Gülay; Bolukcu, Sibel; Sönmez, Ertan; Kaçmaz, Asiye Bahar; Soysal, Pınar; Tan, Semen Gökçe; SOYSAL, PINAR; DURDU, BÜLENT; AKKOYUNLU, YASEMİN; OGUN, HAMZA; OKYALTIRIK, FATMANUR; OKAY, GÜLAY; SÜMBÜL, BİLGE; SÖNMEZ, ERTAN; MERİÇ KOÇ, MELİHA; KAZANCIOĞLU, RÜMEYZA