Person:
ÇAKIR, FATMA BETÜL

Loading...
Profile Picture
Status
Kurumdan Ayrılmıştır.
Organizational Units
Organizational Unit
Job Title
First Name
FATMA BETÜL
Last Name
ÇAKIR
Name
Email Address
Birth Date

Search Results

Now showing 1 - 4 of 4
  • PublicationOpen Access
    Desmoplastic infantile ganglioglioma: Report of an unusual case with a cranial defect.
    (2014-01-01) BASARAN, RUZİYE; Cakir, FATMA BETÜL; ISIK, N; SAV, A; ELMACI, I; BAŞARAN, RUZİYE; ÇAKIR, FATMA BETÜL
  • PublicationOpen Access
    A Difficult Case of Hodgkin Lymphoma with Differential Diagnosis of Tuberculosis and Sarcoidosis.
    (2015-06-08) GÖKNAR, N; Çakır, FATMA BETÜL; KASAPCOPUR, O; YEGEN, G; GEDIK, AH; OKTEM, F; ÇAKIR, ERKAN; ÇAKIR, FATMA BETÜL
    We report here the case of a 14-year-old boy with history of fever, weight loss, and mediastinal lymphadenopathy. The clinical symptoms and laboratory findings mimicking tuberculosis and sarcoidosis complicated the diagnostic process. He was diagnosed with Hodgkin's lymphoma after several X-rays, computed tomography, positron emission tomography-computed tomography, laboratory tests and three lymph node biopsy. Clinicians should be alerted on new lesions and symptoms in high risk patients and should repeat diagnostic tests and lymph node biopsies as indicated.
  • PublicationOpen Access
    Ceftriaxone-induced hemolytic anemia in a child successfully managed with intravenous immunoglobulin
    (2016-03-01) Vehapoglu, AYSEL; GOKNAR, Nilufer; TUNA, Rumeysa; Cakir, FATMA BETÜL; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, FATMA BETÜL
    Drug-induced hemolytic anemia is an immune-mediated phenomenon that leads to the destruction of red blood cells. Here, we present a case of life-threatening ceftriaxone-induced hemolytic anemia (CIHA) in a previously healthy 3-year-old girl. We also reviewed the literature to summarize the clinical features and treatment of hemolytic anemia. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with high mortality. Our patient had a sudden loss of consciousness with macroscopic hematuria and her hemoglobin dropped from 10.2 to 2.2 g/dl over 4 hours, indicating that the patient had life-threatening hemolysis after an intravascular dose of ceftriaxone who had previously been treated with ceftriaxone in intramuscular form for six days. CIHA is associated with a positive direct antiglobulin test, revealing the presence of IgG in all cases and C3d in most cases. Our patient's direct antiglobulin test was positive for IgG (3+) and for C3d (4+). The case was managed successfully with supportive measures and intravenous immunoglobulin therapy. Ceftriaxone is used very frequently in children; an early diagnosis and proper treatment of hemolytic anemia are essential to improve the patient outcome. The pathophysiological mechanism is the same as for non-drug autoimmune hemolytic anemia. However, there is still no consensus treatment for CIHA. Intravenous immunoglobulin can be used in clinical emergencies, such as our case, or in refractory cases.
  • PublicationOpen Access
    False positivity of magnetic resonance imaging under the effect of granulocyte-colony stimulating factor in a child with leukemia
    (2013-06-01) ÇAKIR, FATMA BETÜL; Baysal, Begümhan; Doğan, Öner; ÇAKIR, FATMA BETÜL
    Granulocyte-colony stimulating factor (G-CSF) increases the proliferation and maturation of committed polymorphonuclear leukocyte precursors, as well as the function of mature polymorphonuclear leukocytes. It has previously been shown in pediatric patients that G-CSF induces reconversion of fatty bone marrow to hematopoietic bone marrow in the pelvis and lower extremities that is detectable by magnetic resonance imaging (MRI). Here, we report a 13-year-old Burkitt leukemia patient with bone pain while he was in remission. He was on G-CSF after cessation of high-dose and low-dose cytarabine chemotherapy. He was suspected to have a leukemia relapse. Pelvic MRI was consistent with leukemic infiltration. However, the pathology of bone marrow biopsy resulted in normal findings. Thus it was suggested that concurrent administration of G-CSF could be the causative agent for both bone pain and false-positive MRI findings. The control MRI after interruption of G-CSF revealed normal findings. In conclusion, radiologists should be informed about the type of therapy, including G-CSF administration, in order to overcome misinterpretation of bone marrow MRI.