2018-10-01, ŞENGÜL, YILDIZHAN, ŞENGÜL, HAKAN SERDAR, GÖKÇAL, ELİF, ÜSTÜN, İSMET, ÖZTÜRK, AHMET, YILMAZ, ONUR, YILDIZ, GÜLSEN, ŞENGÜL, YILDIZHAN, GÖKÇAL, ELİF, ÜSTÜN, İSMET, ÖZTÜRK, AHMET, YILMAZ, ONUR

2015-09-01T00:00:00Z, BAKIM, BAHADIR, Sengul, YILDIZHAN, SENGUL, HS, Sural, MK, FORTA, H, ŞENGÜL, YILDIZHAN

2017-11-30, USLU, FERDA, GÖKÇAL, ELİF, ŞENGÜL, YILDIZHAN, KARAKAYALI, ZEHRA CEMRE, UZUN, MUSTAFA, ASIL, TALİP, GÖKÇAL, ELİF, ŞENGÜL, YILDIZHAN, KARAKAYALI, ZEHRA CEMRE, USLU, FERDA, ASİL, TALIP

2018-12-01, Şengül, YILDIZHAN, TUNÇ, ABDULKADİR, YILMAZ, ONUR, ÖZTÜRK, AHMET, ŞENGÜL, YILDIZHAN, TUNÇ, ABDULKADIR, YILMAZ, ONUR, ÖZTÜRK, AHMET

2018-04-01, Şengül, Hakan Serdar, ŞENGÜL, YILDIZHAN, Yücel, Selma, Forta, Hulki, ŞENGÜL, YILDIZHAN

2015-01-01T00:00:00Z, Sengul, YILDIZHAN, SENGUL, Hakan S., Bakim, Bahadir, YUCEKAYA, Sevda K., YUCEL, Selma, AKGUN, Mucella, ŞENGÜL, YILDIZHAN

Many studies have investigated the association between headache and sleep disorders, but few have focused on migraine. The goal of this study was to evaluate sleep disturbance and excessive daytime sleepiness (EDS) in relation to migraine disability. 120 migraine patients who were diagnosed according to The International Classification of Headache Disorders-II and 45 healthy controls were recruited for the study. All participants completed the Pittsburg Sleep Quality Index (PSQI), the Epworth Sleepiness Scale, Beck Depression Inventory and Beck Anxiety Scale. Migraineurs completed Migraine Disability Assessment Scale (MIDAS) and Visual Analog Scale. The prevalence of poor sleep was 83.3% in the patients and 22.2% in the controls. All PSQI subgroup scores were higher for the patients than the controls except Hours asleep. EDS was more prominent in the patient group (19.2% vs 2.2%). In conclusion, sleep disturbance, EDS, anxiety, and depressive symptoms were detected more commonly in migraine patients and were correlated with the migraine-related disability. The results of multivariate regression analysis indicated that EDS and sleep disturbance were the most effective factors on disability.

2017-11-30, Şengül, Hakan Serdar, ŞENGÜL, YILDIZHAN, YILDIZ, GÜLSEN, ŞENGÜL, YILDIZHAN, BABACAN YILDIZ, GÜLSEN

2018-11-01T00:00:00Z, ŞENGÜL, YILDIZHAN, Sengul, Hakan Serdar, Tunc, Abdulkadir, ŞENGÜL, YILDIZHAN

Objective - Migraine is a common and often debilitating disorder. Although the existence of a link between migraine and certain psychological features has long been known, data on dissociative experiences in migraine patients is insufficient. The aim of this study was to evaluate the presence of psychoform and somatoform dissociative experiences among migraine patients without aura and to examine their relationship with pain perception and disability.

2016-09-01T00:00:00Z, Sengul, Hakan Serdar, ŞENGÜL, YILDIZHAN, Yucel, Selma, Forta, Hulki, ŞENGÜL, YILDIZHAN

Objective: In multiple sclerosis (MS); memory, attention, information processing speed, and executive function deficits associated with cortical demyelination and atrophy can be seen in the early phases. In essential tremor (ET) cognitive impairment associated with cerebral-thalamocortical pathway dysfunction, which is characterized by visuospatial functions, verbal memory, and executive functions were seen. We aimed to evaluate cognitive impairment in patients with MS and ET, and to compare the features of impairment.

2021-05-01T00:00:00Z, Sengul, Yildizhan, Temur, Hafize Otcu, Sengul, Hakan S., Ustun, Ismet, Radler, Keith, ALKAN, ALPAY, Louis, Elan D., ŞENGÜL, YILDIZHAN, ÜSTÜN, İSMET, ALKAN, ALPAY

Essential tremor (ET) is a complex, neurodegenerative disorder that includes motor and non-motor symptoms. There is growing interest in its non-motor features, including sleep disturbances (SD). There are no studies evaluating the brain structural correlates of SD in ET. We aimed to identify brain microstructural changes related to SD in ET. SD was evaluated using the Pittsburg sleep quality index (PSQI). Diffusion tensor imaging (DTI), with reported measures being fractional anisotropy (FA) and apparent diffusion coefficient (ADC), was used to evaluate microstructural brain changes. DTI data were compared in ET patients with vs. without SD. The mean age of 40 ET patients was 49.20 +/- 21.06 years. The mean PSQI score was 6.13 +/- 3.99, and 18 (45.0%) patients had SD. The mean PSQI score of patients with vs. without SD was 9.78 +/- 2.98 vs. 3.14 +/- 1.28 (p < 0.001). Patients with vs. without SD differed significantly with respect to several DTI findings: right (R) superior cerebellar peduncle ADC (p = 0.04), left (L) dorsolateral prefrontal cortex FA (p < 0.01), L frontooccipital fasciculus FA (p = 0.02), R posterior corona radiata (RPCR) FA (p = 0.01), L posterior corona radiata FA (p = 0.04), R posterior thalamic radiation (RPTR) FA (p = 0.02), and fornix FA (p = 0.03) Significant correlations between PSQI scores and RPCR FA (r = - 0.50, p = 0.02) and RPTR FA (r = - 0.67, p = 0.001) were also observed. Our findings suggest that certain brain changes may be associated with the clinical expression of SD in ET. These changes are discussed in terms of their possible neuroanatomical and physiological significance.