Person:
ŞENGÜL, YILDIZHAN

Loading...
Profile Picture
Status
Kurumdan Ayrılmıştır
Organizational Units
Organizational Unit
Job Title
First Name
YILDIZHAN
Last Name
ŞENGÜL
Name
Email Address
Birth Date

Search Results

Now showing 1 - 6 of 6
  • PublicationMetadata only
    A comparison between rate of nonmotor symptom development in essential tremor and Parkinson-s disease.
    (2015-09-01T00:00:00Z) BAKIM, BAHADIR; Sengul, YILDIZHAN; SENGUL, HS; Sural, MK; FORTA, H; ŞENGÜL, YILDIZHAN
  • PublicationMetadata only
    Sleep disturbances and excessive daytime sleepiness in migraine: A comparison between comorbidities and disability
    (2015-01-01T00:00:00Z) Sengul, YILDIZHAN; SENGUL, Hakan S.; Bakim, Bahadir; YUCEKAYA, Sevda K.; YUCEL, Selma; AKGUN, Mucella; ŞENGÜL, YILDIZHAN
    Many studies have investigated the association between headache and sleep disorders, but few have focused on migraine. The goal of this study was to evaluate sleep disturbance and excessive daytime sleepiness (EDS) in relation to migraine disability. 120 migraine patients who were diagnosed according to The International Classification of Headache Disorders-II and 45 healthy controls were recruited for the study. All participants completed the Pittsburg Sleep Quality Index (PSQI), the Epworth Sleepiness Scale, Beck Depression Inventory and Beck Anxiety Scale. Migraineurs completed Migraine Disability Assessment Scale (MIDAS) and Visual Analog Scale. The prevalence of poor sleep was 83.3% in the patients and 22.2% in the controls. All PSQI subgroup scores were higher for the patients than the controls except Hours asleep. EDS was more prominent in the patient group (19.2% vs 2.2%). In conclusion, sleep disturbance, EDS, anxiety, and depressive symptoms were detected more commonly in migraine patients and were correlated with the migraine-related disability. The results of multivariate regression analysis indicated that EDS and sleep disturbance were the most effective factors on disability.
  • PublicationMetadata only
    Evaluation of thickness of retinal nerve fiber layer, ganglion cell layer, and choroidal thickness in essential tremor: can eyes be a clue for neurodegeneration?
    (2018-06-01) Tak, Ali Zeynel Abidin; Sengul, YILDIZHAN; Karadag, Ayse Sevgi; ŞENGÜL, YILDIZHAN
    The pathology of essential tremor (ET) and underlying mechanisms of the disease are still unclear, but an increasing amount of research has been conducted on the subject. Discussions are ongoing about ET-s definition as a neurodegenerative disease. Optic coherence tomography (OCT) provides a window to the brain where direct visualization of central nervous system (CNS) changes may be possible, and it can help us to develop a new point of view on ET. The goal of this study was to examine OCT parameters in ET. 40 ET patients and 40 healthy controls, i.e., a total of 160 eyes were evaluated. Retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and choroid thinning were analyzed using spectral domain OCT. The mean age was 25.77 +/- 8.98 in the ET group and 27.25 +/- 8.22 in the control group. We found a decreased global RNFL thickness for both eyes in ET patients. All GCL and IPL thickness parameters were lower in the patients with ET (P < 0.001, P 0.03). Choroid was significantly thicker in ET patients than the controls (P < 0.001). Our study-s results suggest that the usefulness of OCT in detecting neurodegeneration in ET. RNFL, GCL, IPL measurements are highly reproduced findings of neurodegeneration. Increased choroid volume may indicate neuroinflammation. Eyes in ET may shed light on nature of the disease, and may be used as a diagnostic tool.
  • PublicationMetadata only
    Evaluation of white matter hyperintensities and retinal fiber layer, ganglion cell layer, inner-plexiform layer, and choroidal layer in migraine patients
    (2018-03-01) Tak, Ali Zeynel Abidin; Sengul, YILDIZHAN; Bilak, Semsettin; ŞENGÜL, YILDIZHAN
    The aim of our study is to assess retinal nerve fiber layer (RNFL), the ganglion cell layer (GCL), inner-plexiform layer (IPL), and choroidal layer in migraine patients with white matter lesion (WML) or without WML, using spectral domain optical coherence tomography (OCT). To our study, 77 migraine patients who are diagnosed with migraine in accordance to the International Classification of Headache Disorders (ICHD)-3 beta and 43 healthy control are included. In accordance to cranial MRI, migraine patients are divided into two groups as those who have white matter lesions (39 patients), and those who do not have a lesion (38 patients). OCT was performed for participants. The average age of participants was comparable. The RNFL average thickness parameter in the migraine group was significantly lower than in the control group (p < 0.01). However, no significant difference was detected among those migraine patients who have WML, and those who do not have. No significant difference is detected among all groups in terms of IPL, GCL, and choroidal layer measuring scales. The proofs showing that affected retinal nerve fiber layer are increased in migraine patients. However, it is not known whether this may affect other layers of retina, or whether there is a correlation between affected retinal structures and white matter lesions. In our study, we found thinner RNFL in migraine patients when we compared with controls but IPL, GCL, and choroid layer values were similar between each patient groups and controls. Also, all parameters were similar between patients with WML and without WML. Studies in this regard are required.
  • PublicationMetadata only
    Is it true that essential tremor affects sleep? A comparison between young essential tremor patients and normal controls
    (2015-10-01T00:00:00Z) Sengul, YILDIZHAN; SENGUL, Hakan; ŞENGÜL, YILDIZHAN
    Essential tremor (ET) is the most common movement disorder and cause of functional disability. ET is known as a monosymptomatic, pure motor system disease. This interpretation of ET has been questioned in the last decade. Non-motor symptoms have added to the definition of the disease. In autopsy studies, it has been reported that Lewy bodies are common in the locus coeruleus, which is known to have an active role in sleep. Previous research about sleep in ET has studied older patients. Sleep disturbances are common in older adults. Our study focused on younger patients who had the disease for a shorter period of time. 40 patients (24.9 +/- 7.0 years old) and 28 controls were recruited for the study. Sleep quality was evaluated with the Pittsburg Sleep Quality Index (PSQI). Excessive daytime sleepiness (EDS) was evaluated with the Epworth Sleepiness Scale (ESS). For assessing the possible impact of depression and anxiety on sleep we used the Beck Depression Inventory (BDI), and the Beck Anxiety Scale (BAS). We ruled out other possible causes of tremor. Tremor was evaluated using the Fahn Tolosa Marin Tremor Rating Scale (FTM-TRS). We concluded that although ET patients had bad sleep quality, this might be associated with increased anxiety levels. Mean ESS scores were higher in the patient group, but this was not statistically significant.
  • PublicationMetadata only
    Cognitive functions, fatigue, depression, anxiety, and sleep disturbances: assessment of nonmotor features in young patients with essential tremor.
    (2015-09-01T00:00:00Z) Sengul, YILDIZHAN; SENGUL, HS; YUCEKAYA, SK; YUCEL, S; BAKIM, B; PAZARCı, NK; ÖZDEMIR, G; ŞENGÜL, YILDIZHAN