Person: İNAN, BEKİR
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Publication Open Access Aortic Dissection In Case with Chronic Kidney Disease(2017-10-01) Buyukaydin, BANU; Alay, Murat; Kazancioglu, RÜMEYZA; UGUR, Aycan; Tunc, MUHAMMED; TEKER, Melike Elif; Inan, BEKİR; ERKOC, Reha; BÜYÜKAYDIN, BANU; KAZANCIOĞLU, RÜMEYZA; TUNÇ, MUHAMMED; İNAN, BEKİRAortic disection is an urgent clinical problem that rapid diagnosis and appropriate treatment is life-saving. Hypertension is one of the major risk factors. In this paper, a 56 years old female patient with hypertension and renal failure was presented. In this case after clinical suspicion aortic dissection was diagnosed with imaging studies. Endovascular aortic repair was performed but after surgery, patient died because of possible hemorrhage complication.Publication Open Access Effects of ischemic preconditioning and iloprost on myocardial ischemia-reperfusion damage in rats(2013-01-01) Ay, YASİN; Kara, Ibrahim; Aydin, CEMALETTİN; TEKER, Melike Elif; Senol, Serkan; Inan, BEKİR; BASEL, Halil; Uysal, Omer; Zeybek, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; UYSAL, ÖMER; ZEYBEK, RAHMİThis study investigates the effects of cardiac ischemic preconditioning and iloprost on reperfusion damage in rats with myocardial ischemia/reperfusion. 38 male Wistar Albino rats used in this study were divided into 5 groups. The control group (Group 1) (n=6), ischemia/reperfusion (IR) group (Group 2) (n=8), cardiac ischemic preconditioning (CIP) group (Group 3) (n=8), iloprost (ILO) group (Group 4) (n=8), and cardiac ischemic preconditioning + iloprost (CIP+ILO) group (Group 5) (n=8). Pre-ischemia, 15 minutes post-ischemia, 45 minutes post-reperfusion, mean blood pressure (MBP), and heart rates (HR) were recorded. The rate-pressure product (RPP) was calculated. Post-reperfusion plasma creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), troponin (cTn) vlaues, and infarct size/area at risk (IS/AAR) were calculated from myocardial tissue samples. Arrhythmia and ST segment elevations were evaluated during the ischemia and reperfusion stages. Although the MBP, HR, RPP values, biochemical parameters of CK-MB and LDH levels, IS/AAR rates, ST segment elevation values were found to be similar in CIP and CIP+ILO groups and the IR and ILO groups (p>0.05), CIP-containing group values had a positively meaningful difference (p<0.05) compared with the IR and ILO group. While mild-moderate findings of damage were observed in Group 3 and Group 5, severely findings of damage were releaved in Group 2 and Group 4. The arrhythmia score of the ILO group was meaningfully lower (F: 41.4, p<0.001) than the IR group. We can conclude that the effects of myocardial reperfusion damage can be reduced by cardiac ischemic preconditioning, intravenous iloprost reduced the incidence of ventricular arrhythmia associated with reperfusion, and its use with CIP caused no additional changes.Publication Open Access Straight versus S-shaped sternotomy: a histologic study in the sheep model(2014-10-01) KÜÇÜKDURMAZ, FATİH; İNAN, BEKİR; KÜÇÜKDURMAZ, FATİHIntroduction: Straight sternotomy is the most common access for open heart surgery. Techniques have been proposed for maximizing sternal stability in high-risk patients. This trend implies a growing need for newer surgical techniques. The aim of this experimental study in the sheep model is to evaluate median vs. S shaped sternotomy the feasibility of using a special device to accelerate the sternal instability and bone healing. Materials and methods: We enrolled 31 sheep, weighing 18–30 kg. For all animals a midline skin incision was made. In group I (n = 16 animals), straight median sternotomy and in group II (n = 15 animals), S-shaped incision was marked on the periosteum of the sternum by new created device for standard S-shaped sternotomy. Sternum biopsies were performed on second surgery month for all survived animals from the sternum and the surrounding soft tissue. Results: No early superficial wound complications were observed. Overall mortality in the initial approach group was 19.3% (6 sheep). In group I; 3 sheep had died on first surgery day, the reason may be hemorrhage and in group II; 3 sheep developed intractable VF during surgery procedure or immediately afterwards so died. There were statistically significant differences in the scores of bone healing between group 1 and group 2 (4.2 vs.7.3, ANOVA, p < 0.001). Discussion: Our work is based on the use of a standard S-shaped sternotomy procedure on sheep sternum. In our experience with the sternal healing in the sheep model, the process of new bone formation was accelerated with S- shaped cut than straight sternotomy procedurePublication Open Access Surgical treatment of lower limb ischemia in diabetic patients - long-term results(2013-12-01T00:00:00Z) İNAN, BEKİR; Aydin, Unal; Ugurlucan, Murat; AYDIN, CEMALETTİN; Teker, Melike Elif; İNAN, BEKİR; AYDIN, CEMALETTİNIntroduction: Lower limb ischemia may cause nonhealing ulcers, infection, amputation and even mortality in diabetic patients. In this study, we review our data of ischemic lower limb revascularization procedures in diabetic patients and present the early, mid- and long-term results.Publication Open Access Comparison of the Health Related Quality of Life of Patients Following Mitral Valve Surgical Procedures in the 6-Months Follow-up: A Prospective Study(2013-04-01T00:00:00Z) AY, YASİN; KARA, İBRAHİM; AYDIN, CEMALETTİN; KAHRAMAN AY, Nuray; İNAN, BEKİR; Basel, Halil; ZEYBEK, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; ZEYBEK, RAHMİPurpose: The aim of the present study is to evaluate the health-related quality of life of the patients who underwent mitral valve repair (MvRp) and mitral valve replacement (MVR).Publication Open Access Venous Insufficiency in Pediatric Patients(2019-10-01T00:00:00Z) Acikel, Melike Elif Teker; İNAN, BEKİR; İNAN, BEKİRObjective: The diagnosis and treatment of chronic venous disease has been well standardized in adults. However, the diagnosis of chronic venous insufficiency in pediatric patients, except for Klippel-Trenaunay syndrome and post-thrombotic syndrome, could not be established. In this retrospective study, we planned to present pediatric patients diagnosed with venous insufficiency by our clinic. Methods: Between January 2016 and May 2018, patients under 18 years of age who were referred to our clinic were included in this study. Venous Doppler ultrasonography was performed in patients and reflux in deep and superficial veins was evaluated. The reflux time is simply duration of inverse flow. A reflux time of >500 ms was used to define the valve insufficiency of the superficial and perforating veins. A reflux time of >1 s was used to define the valve insufficiency of the deep venous system. Venous reflux parameters were compared using t-test. Results: Twenty-five patients were identified in this study. The mean age of the patients was 12 (4-17) years. As a result of clinical examination, 11 patients had varicose venous or venous malformation, 9 patients had swelling (pedal edema), and 6 patients had edema or venous ulcer. Two patients had normal examination findings. Chronic inflammation, hyperpigmentation was not present. No venous thrombomboemboli story was available in any patient. Conclusion: The uncertainty of the factors that cause venous reflux in children still maintains itself today. However, this uncertainty will continue for a long time as the methods used in the diagnosis and treatment of chronic venous disease are the same in both adults and children.