Person: KURT, GÖKMEN
7 results
Search Results
Now showing 1 - 7 of 7
Publication Metadata only Effectiveness of incremental vs maximum bite advancement during Herbst appliance therapy in late adolescent and young adult patients](2019-01-01) Amuk, Nisa Gul; Baysal, Asli; Coşkun, Ramadan; Kurt, GÖKMEN; KURT, GÖKMENIntroduction: The purpose of this research was to compare the effects of Herbst appliance therapy using incremental vs maximum advancement in late adolescent and young adult patients with Class II skeletal malocclusion. Methods: Forty-two patients with skeletal Class II malocclusion were treated with cast-splint Herbst appliances. The subjects were randomly allocated into 2 groups according to activation type: incremental advancement (IA) and maximum advancement (MA). Initial forward movement in the IA group was 4 to 5 mm and was followed by subsequent bimonthly advancements of 2 mm. Single-step advancement was achieved in the MA group until an edge-to-edge incisor relationship or an overcorrected Class I molar relationship was obtained. Total treatment times were 9.7 +/- 1.1 months for the IA group and 9.5 +/- 1.1 months for the MA group. Dental, skeletal, and soft tissue measurements were performed on lateral cephalograms taken just before and at the end of the Herbst appliance therapy. Statistical significance was set at P <= 0.05. Results: All mandibular skeletal dimensions increased, and improvements of the sagittal maxillomandibular parameters were found in both groups. Protrusion and proclination of the mandibular incisors were greater in the IA group (95.90 degrees +/- 5.34 degrees) compared with the MA group (92.04 degrees +/- 7.92 degrees). Other dentoalveolar changes in both groups were intrusion of the maxillary first molars, and extrusion of the mandibular first molars and maxillary incisors. The mentolabial sulcus was flattened, soft tissue convexity was reduced, and forward movement of mandibular soft tissues was seen after Herbst therapy. Conclusions: Similar skeletal, dental, and soft tissue changes were obtained in both groups after Herbst therapy. Greater proclination and more protrusion of the mandibular incisors were found in the IA group.Publication Metadata only Effects of cell-mediated osteoprotegerin gene transfer and mesenchymal stem cell applications on orthodontically induced root resorption of rat teeth(2017-06-01T00:00:00Z) Amuk, Nisa Gul; Kurt, GÖKMEN; Baran, Yusuf; Seyrantepe, Volkan; Yandim, Melis Kartal; Adan, Aysun; Demir, Secil Akyildiz; Kiraz, Yagmur; Sonmez, Mehmet Fatih; KURT, GÖKMENAim: The aim of this study is to evaluate and compare therapeutic effects of mesenchymal stem cell (MSCs) and osteoprotegerin (OPG) gene transfer applications on inhibition and/or repair of orthodontically induced inflammatory root resorption (OIIRR).Publication Metadata only Effects of Photobiomodulation and Ultrasound Applications on Orthodontically Induced Inflammatory Root Resorption; Transcriptional Alterations in OPG, RANKL, Cox-2: An Experimental Study in Rats(2018-12-01) Amuk, Nisa Gul; Kurt, GÖKMEN; Güray, Enis; KURT, GÖKMENObjective: The aim of this study was to evaluate and compare the reparative and inhibitory effects of a light-emitting diode-mediated photobiomodulation (PBM) and of a low-intensity pulsed ultrasound (LIPUS) on orthodontically induced inflammatory root resorption (OIIRR). Materials and methods: Forty-nine Wistar rats were divided into four groups: untreated group (negative control), group treated with orthodontic appliances (positive control), PBM-treated group (wavelength: 618 nm, output power density: 20 mW/cm(2)), and LIPUS-treated group (frequency: 1.5% +/- 5% MHz, pulse repetition ratio: 1.0% +/- 10% kHz, effect area: 3.88% +/- 1% cm(2) and intensity: 30% +/- 30% mW/cm(2)). OIIRR was induced experimentally in rats for 14 days with an applied force of 100g, and therapeutic approaches were performed concurrently. At the end of the experiment, upper first molar teeth of rats were prepared for genetic analysis, scanning electron microscopy, hematoxylin and eosin staining, and tartrate-resistant acid phosphatase staining. Kruskal-Wallis and post hoc Dunn-s tests were performed. Results: Number of osteoclasts (p < 0.01), number of resorption lacunae and resorption area ratio (p < 0.001) decreased and number of total cells (p < 0.001) increased with the PBM and LIPUS applications when compared with the positive control group. Receptor activator of nuclear factor kappa B ligand (RANKL) levels of PBM and LIPUS groups were lower (p < 0.001), and osteoprotegerin (OPG) levels were higher (p < 0.001) than the positive control group. Cyclooxygenase-2 (Cox-2) expression significantly decreased with LIPUS and PBM administrations (p < 0.05). No significant difference was observed among PBM and LIPUS groups. Conclusions: PBM and LIPUS applications showed marked inhibitory and reparative effects on OIIRR by modulating the OPG/RANKL ratio, Cox-2 expression, and cell differentiation of osteoblasts and osteoclasts.Publication Metadata only Changes in pharyngeal airway dimensions following incremental and maximum bite advancement during Herbst-rapid palatal expander appliance therapy in late adolescent and young adult patients: a randomized non-controlled prospective clinical study(2019-06-01T00:00:00Z) Amuk, Nisa Gul; KURT, GÖKMEN; Baysal, Asli; Turker, Gokhan; KURT, GÖKMENObjectives: This was a parallel, assessor-blinded, randomized, non-controlled prospective trial with the objective to evaluate and compare the effects of maximum advancement (MA) and incremental advancement (IA) of mandible with cast-splint-type Herbst-rapid palatal expander (RPE) appliance on pharyngeal airway dimensions and hyoid bone position in skeletal Class II late adolescents and young adults.Publication Metadata only Incremental versus maximum bite advancement during Herbst therapy response(2019-06-01T00:00:00Z) Amuk, Nisa Gul; Baysal, Asli; Coskun, Ramadan; Kurt, GÖKMEN; KURT, GÖKMENPublication Metadata only Effects of mesenchymal stem cell transfer on orthodontically induced root resorption and orthodontic tooth movement during orthodontic arch expansion protocols: an experimental study in rats(2020-06-01T00:00:00Z) Amuk, Nisa Gul; KURT, GÖKMEN; Karsli, Erol; ÖZCAN, SERVET; Acar, Mustafa Burak; AMUK, MEHMET; LEKESİZCAN, AYÇA; Gurgan, Cem Abdulkadir; KURT, GÖKMENObjectives: The aim was to evaluate the effects of mesenchymal stem cell (MSC) transfer to periodontal ligament (PDL) on the inhibition and/or repair of orthodontically induced root resorption (OIRR) during and after arch expansion and on the orthodontic tooth movement (OTM) rate of the maxillary first molar teeth of rats.Publication Metadata only Evaluation of Time-Dependent Temperature Changes during Different Interdental Stripping Procedures by Thermal Imaging: An In Vitro Study(2019-11-01T00:00:00Z) Amuk, Nisa Gul; KURT, GÖKMEN; Cakmak, Gulsen; Er, Ozgur; KURT, GÖKMENPurpose: To investigate the temperature changes in pulp chamber of incisor and canine teeth during different stripping procedures with thermal imaging.