Person: HAKYEMEZ, İSMAİL NECATİ
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- PublicationMetadata onlyPlatelet parameters in hepatic hydatid cysts(2013-07-01T00:00:00Z) Sit, Mustafa; Aktaş, Gülali; Yilmaz, Edip Erdal; Hakyemez, Ismail Necati; Alçelik, Aytekin; Küçükbayrak, Abdülkadir; HAKYEMEZ, İSMAİL NECATİ
- PublicationMetadata onlySeroprevalence of Rubella in northeastern Turkey(2013-07-01) Akkoyunlu, YASEMİN; Arvas, Gulhan; OZSARI, Tamer; Hakyemez, Ismail Necati; KAYA, Bulent; ASLAN, Turan; AKKOYUNLU, YASEMİN; HAKYEMEZ, İSMAİL NECATİAim The aim of this study was to search rubella prevalence and compare the results with national and international data.
- PublicationOpen AccessLung cancer, brucellosis and tuberculosis: Remarkable togetherness(2013-08-01) Akkoyunlu, MUHAMMED EMİN; AKKOYUNLU, YASEMİN; Hakyemez, Ismail Necati; Erboy, Fatma; ARVAS, Gulhan; ASLAN, Turan; AKKOYUNLU, MUHAMMED EMİN; AKKOYUNLU, YASEMİN; HAKYEMEZ, İSMAİL NECATİ
- PublicationMetadata onlyEvaluation of patients with Tularemia in Bolu province in northwestern Anatolia, Turkey(2014-03-01T00:00:00Z) Mengeloglu, Zafer; Duran, Arif; Hakyemez, Ismail Necati; Ocak, Tarik; Kucukbayrak, Abdulkadir; KARADAG, Mustafa; Tas, Tekin; Akdeniz, Hayrettin; HAKYEMEZ, İSMAİL NECATİIntroduction: Tularemia is a zoonotic disease caused by Francisella tularensis. Here we present an epidemic occurring in Bolu province, located in northwestern Anatolia in Turkey, and some features of the cases.
- PublicationOpen AccessAnalysis of infectious spondylodiscitis: 7-years data(2018-11-01) Koc, Meliha Meric; Okay, GÜLAY; Akkoyunlu, YASEMİN; Bolukcu, SİBEL; Durdu, BÜLENT; Hakyemez, Ismail Necati; OKAY, GÜLAY; AKKOYUNLU, YASEMİN; BOLUKÇU, SİBEL; DURDU, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; MERİÇ KOÇ, MELİHAObjective: Infectious spondylodiscitis (SD) is an infectious disease that is rare and difficult to diagnose due to its non-specific clinical features. In this study, we aimed to describe the clinical and diagnostic features of infectious spondylodiscitis. Methods: All patients who were diagnosed with SD at our hospital during a 7-year period from January 1, 2011 through December 31, 2017 were included in the study. Spondylodiscitis is divided into the following three types: pyogenic, tuberculous, and brucellar. Clinical and laboratory data were collected retrospectively from the medical records of the patients. Results: Of the 118 patients, 66 (55.9%) were female, 81 (68.6%) had pyogenic SD (PSD), 21 (17.8%) had tuberculous SD (TSD), and 16 (13.6%) had brucellar SD (BSD). The mean age was 59.3 ± 14.6 years. Leucocytosis was significantly higher in patients with PSD (p=0.01) than in patients with other types of SD. Thoracic involvement (47.6%) was significantly higher in patients with TSD (p=0.005) than in other patients. Sacral involvement (12.5%) was significantly higher in patients with BSD (p=0.01) than in other patients. Paravertebral abscess formation (42.8%) occurred most frequently in patients with TSD. Microbiologic agents were defined in 50% (18/36) of the surgical specimens and in 12.5% of the fine needle aspiration biopsy (FNAB) specimens. Staphylococcus aureus was the most common microbiological agent in patients with PSD. Spinal surgery was defined as a risk factor for PSD (p = 0.0001). Binary logistic regression analysis revealed that female gender, thoracic involvement and night sweats were the predictive markers for TSD (OR 4.5 [95% CI 1.3-15.3] and OR 5 [95% CI 1.7-14.6]). Conclusion: PSD is the most frequent form of SD. Leucocytosis is most common in patients with PSD. Thoracic involvement and paraspinal abscess were prominent in patients with TSD. Sacral involvement was most common in patients with BSD. Thoracic involvement, female gender and night sweats were the predictive markers for TSD. The microbiological culture positivity rate was higher in surgical specimens compared to FNAB specimens. The need for surgical treatment was most common in patients with TSD.
- PublicationMetadata onlyRed Cell Volume Distribution Width to Platelet Ratio is an Important Predictor of Liver Fibrosis and Cirrhosis in Chronic Hepatitis B(2016-08-01) Hakyemez, Ismail Necati; BOLUKÇU, SİBEL; Durdu, BÜLENT; ASLAN, Turan; HAKYEMEZ, İSMAİL NECATİ; BOLUKÇU, SİBEL; DURDU, BÜLENTObjective: In recent years, a lot of non-invasive tests have been examined for estimating the severity of liver fibrosis in patients with chronic hepatitis B (CHB). We aimed to evaluate the role of simple and valuable platelet-derived indices in estimating the stage of fibrosis and cirrhosis in patients with CHB.
- PublicationMetadata onlyTakayasu arteritis initially mimicking infective endocarditis(2011-01-01T00:00:00Z) Alcelik, Aytekin; Karacay, Sevim; Hakyemez, Ismail Necati; Akin, Busra; Ozturk, Serkan; Savli, Haluk; HAKYEMEZ, İSMAİL NECATİ
- PublicationMetadata onlyDetermining immunoassay cutoff value using Western blot results to predict hepatitis C infection in blood donors with low-titer anti-HCV reactivity(2013-07-01T00:00:00Z) Kucukbayrak, Abdulkadir; CAKMAK, Saadet; Hakyemez, Ismail Necati; Tas, Tekin; Akdeniz, Hayrettin; HAKYEMEZ, İSMAİL NECATİSince the 1990s, blood donors have been scanned for anti-hepatitis C virus (anti-HCV) antibodies, which can be defined by enzyme immunoassay as a screening test. In this population, false-reactive ratios have been high. Recently, some authors have aimed to find a cutoff value for anti-HCV different from those established by test manufacturers to predict HCV infection. In this study, 321 patients, after two repeating tests, had reactive results in s/co 2.61 s/co, with 74.1 % sensitivity and 71.6 % specificity (area under the curve, 0.820; 95 % confidence interval, 0.753 to 0.887). We suggest that an effective cutoff value for anti-HCV other than that established by the manufacturer cannot be assigned to predict hepatitis C infection for blood donors in low-prevalence areas.
- PublicationMetadata onlyInfective endocarditis case due to streptococcus parasanguinis presented with spondylodiscitis(2016-01-01) Hakyemez, Ismail Necati; Durdu, BÜLENT; Okay, GÜLAY; GULTEPE, Bilge; Bolukcu, SİBEL; ASLAN, Turan; HAKYEMEZ, İSMAİL NECATİ; DURDU, BÜLENT; OKAY, GÜLAY; BOLUKÇU, SİBEL; SÜMBÜL, BİLGEStreptococcus parasanguinis is a natural member of oral flora. It is an opportunistic pathogen, and rarely cause systemic infections due to it-s low virulence. Subacute infective endocarditis may present with various clinical manifestations (eg., spondylodiscitis). A sixty-five years old male patient from Northern Iraq has referred to our emergency service with high fever, weight loss, back pain and inability to walk. The patient was a veterinarian. He was operated three years ago for colonic carcinoma and irradiated. In magnetic resonance imaging, spondylodiscitis was detected localized in lumbar 1-2 region. Transthorasic echocardiography demonstrated aortic valve vegetation. S. parasanguinis was identified in the blood cultures. In conclusion; all in all, it-s remarkable to isolate S. parasanguinis as a causal agent of infective endocarditis in a patient who is a veterinarian with history of colonic carcinoma presented with clinical manifestation of spondylodiscitis.
- PublicationOpen AccessMortality markers in nosocomial Klebsiella pneumoniae bloodstream infection(2016-10-28) Durdu, BÜLENT; Hakyemez, Ismail Necati; BOLUKÇU, SİBEL; OKAY, GÜLAY; ASLAN, Turan; DURDU, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; BOLUKÇU, SİBEL; OKAY, GÜLAY; SÜMBÜL, BİLGEPurpose: Klebsiella pneumoniae is the most common endogen agent for nosocomial infections. In this study, mortality markers were investigated in patients with nosocomial K. pneumoniae blood stream infection (NKp BSI). Methods: The characteristics of patients >16 years who had NKp BSI diagnosis by daily active surveillance between January 2012 and January 2016 were retrospectively evaluated. Patients who died until 28th day of the clinical follow up and those who survived until this time were statistically compared in terms of various risk factors. Results: One hundred ninety patients were included into the study. Mortality rate was 47.9%, carbapenem resistance was 43.2%. Statistical analysis have shown that in presence of post-NKp BSI sepsis, septic shock, following in intensive care unit (ICU), meropenem resistance, kidney failure, NKp BSI secondary to pneumonia, use of invasive instruments such as central venous catheter (CVC), urinary catheter (UC) and mechanical ventilator (MV), colostomy, transfusion and hemodialysis mortality was significantly higher. In patients admitted into the hospital for neurological disorders, pancreaticobiliary tract (PBT) diseases and patients who have undergone endoscopic retrograde cholangiopancreatography (ERCP) and patients in whom NKp BSI secondary to PBT infection mortality rate was lower. Conclusions: Sepsis, septic shock, clinical conditions requiring ICU treatment and meropenem resistance increase mortality rates in NKp BSI significantly. Mortality was higher also in patients with NKp BSI secondary to pneumonia, in kidney failure and when invasive instruments were used. On the other hand, in patients who were admitted to the hospital for neurological disorders and PBT diseases mortality rate was lower.