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TEKÇE, ERTUĞRUL

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ERTUĞRUL
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TEKÇE
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Radiation therapy for squamous cell cancer of the skin in a patient with xeroderma pigmentosum

2022-06-01T00:00:00Z, Altinok, Pelin, Tekçe, ERTUĞRUL, Ergün, Selmasönmez, Mayadagli, Alpaslan, TEKÇE, ERTUĞRUL, MAYADAĞLI, ALPASLAN

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Clinical evaluation of simultaneous integrated boost in brain metastasis patients with helical intensity modulated radiotherapy

2018-04-01, KIZILTAN, HURİYE ŞENAY, ERIS, A.H., MERAL, İSMAİL, SEYITHANOGLU, H., DÜNDAR, TOLGA TURAN, EREN, F., UNVER, NURCAN, AYDIN, TEOMAN, MAYADAĞLI, ALPASLAN, BAYIR, A.G., CELIKTEN, M., KIZILTAN, HURİYE ŞENAY, MERAL, İSMAİL, DÜNDAR, TOLGA TURAN, TEKÇE, ERTUĞRUL, ÜNVER, NURCAN, AYDIN, TEOMAN, MAYADAĞLI, ALPASLAN

Background: This study was performed to assess patient survival and treatment toxicity after helical tomotherapy (HT) with simultaneous integrated boost (SIB) radiotherapy (RT) for cancer patients with one to eight brain metastases (BM) who have been treated with or without surgery. Materials and Methods: A total of 48 brain metastasis (BM) patients were included in this retrospective study between April 2015 and December 2016,. The patients were treated with image-guided intensity modulated radiation therapy (IMRT) on the helical tomotherapy (HT) machine. Whole brain HT as 25 Gy and SIB to metastasis sites as 35 Gy was delivered in 10 fractions. The patient were aged between 50 to 80 years old, volume of the BM was between 6 to 75 cc and the number of brain metastasis was between 1 to 8, Karnofsky Performance Score (KPS) ranged between 50-90 and RPA I-III. Surgery was performed to two patients before RT. The maximum patient follow-up time was 20 months. Results: The primary neurotoxicity observed in patients was grade I- II brain edema related headache and lethargy. In patients who had survived 3- 12 months, KPS improved median score of 20 points and RPA was grade I after six months. Twelve patients had passed away at the end of a 20- month follow-up. Conclusion: HT utilizing SIB treatment for 1- 8 BM was achieved successfully with no significant toxicity. An improvement of performance status indicators of patients following RT was observed.

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Can low-dose radiotherapy volumes be one of the contributing factors to early relapses in lung cancer patients?

2018-03-01T00:00:00Z, Kiziltan, Huriye Senay, MAYADAĞLI, Alpaslan, TEKÇE, ERTUĞRUL, ERİŞ, ALİ HİKMET, Kablan, Ozgur, Altinok Sut, Pelin, KIZILTAN, HURİYE ŞENAY, MAYADAĞLI, ALPASLAN, TEKÇE, ERTUĞRUL, ERİŞ, ALİ HİKMET, KABLAN, ÖZGÜR, ALTINOK SÜT, PELİN

© 2018 The Authors. Precision Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Shandong Cancer Hospital & Institute.Objective: Several studies have shown that low-dose radiotherapy (RT) might increase tumor invasion and metastases. Whereas multiple RT fields that increase low-dose RT areas are often used to prevent damage to organs at risk. We carried out a clinical trial with the concern that low-dose RT sites could increase invasions or metastases when multiple sites were used. Methods: A clinical retrospective study was carried out on 50 lung cancer patients with stage II–IIIB cancer, who underwent RT and/or chemotherapy, had Eastern Cooperative Oncology Group performances 1–3, were aged 45–87 years, and without metastases. RT was carried out for 5 days with 180–200 cGy fractions per day with a total dose of 54–66 Gy. The radiation dose volume areas V5, V10, V20, V40, V50, and V60 of lung were calculated and analyzed by Mann–Whitney U-test and L par test on disease-free and overall survival statistically. Results: It was determined that V5, V10, and V20, which constitute the low RT dose areas of the lung, positively affected the recurrence-free and overall survival minimally according to r correlation values. Conclusion: Low-dose RT volumes were positively affected minimally by recurrence-free survival and overall survival in the present study. The effects of low-dose radiation must be evaluated more clearly in studies.

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Low dose radiotherapy after the sonodynamic and photodynamic therapy with spirulina for relapsed cancer treatment: With literature review and three case reports

2018-08-01, KIZILTAN, HURİYE ŞENAY, ERIS, ALİ HİKMET, TEKÇE, ERTUĞRUL, AYDIN, TEOMAN, KABLAN, ÖZGÜR, MAYADAĞLI, ALPASLAN, KIZILTAN, HURİYE ŞENAY, ERİŞ, ALİ HİKMET, TEKÇE, ERTUĞRUL, AYDIN, TEOMAN, KABLAN, ÖZGÜR, MAYADAĞLI, ALPASLAN

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FDG PET/CT findings in a rare case of synchronous primary malignant pericardial mesothelioma and nasopharyngeal carcinoma

2019-02-01, Erdoğan, Ezgi Başak, Mayadağlı, Alpaslan, Tekçe, Ertuğrul, ERDOĞAN, EZGİ BAŞAK, MAYADAĞLI, ALPASLAN, TEKÇE, ERTUĞRUL

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PublicationOpen Access

Effects of Low-Dose Radiation on the Survival of Lung Cancer Patients

2018-04-01, Kiziltan, HURİYE ŞENAY, Mayadagli, ALPASLAN, Eris, ALİ HİKMET, Kablan, Ozgur, TURAN, Sezgi, EVREN, Evrim, SUT, Pelin Altinok, Tekce, ERTUĞRUL, BAYIR, Ayse Gunes, KIRSEVER, Esra, KIZILTAN, HURİYE ŞENAY, MAYADAĞLI, ALPASLAN, ERİŞ, ALİ HİKMET, KABLAN, ÖZGÜR, TEKÇE, ERTUĞRUL

Objective: Some previous studies have shown that low-dose radiotherapy (RT) can increase tumor invasion and metastasis. Multiple RT fields are usually used to prevent the damage to the organs at risk. We performed a clinical study with a concern that low-dose RT might increase invasion or metastasis. Ionizing radiation (IR) can enhance the potential tumor micro-environment by modifying the host micro-metastatic cancer cells.

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Düşük doz radyoterapi volümlerinin akciğer kanseri hastalarında yaşam üzerine etkileri

2017-07-01, KIZILTAN, HURİYE ŞENAY, MAYADAĞLI, ALPASLAN, ERİŞ, ALİ HİKMET, KABLAN, ÖZGÜR, EROĞUZ, SEZGİ TURAN, EVRİM, EVREN, ALTINOK SÜT, PELİN, TEKÇE, ERTUĞRUL, GÜNEŞ BAYIR, AYŞE, KIRSEVER, ESRA, KIZILTAN, HURİYE ŞENAY, MAYADAĞLI, ALPASLAN, ERİŞ, ALİ HİKMET, KABLAN, ÖZGÜR, ALTINOK SÜT, PELİN, TEKÇE, ERTUĞRUL, GÜNEŞ BAYIR, AYŞE

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Diş CBCT ile oluşan tiroid üzerindeki radyasyon doz etkisinin gösterilmesi

2018-02-01, ERİŞ, ALİ HİKMET, KIZILTAN, HURİYE ŞENAY, KABLAN, ÖZGÜR, TEKÇE, ERTUĞRUL, BERK, KEMAL, ÜNVER, TUBA, MAYADAĞLI, ALPASLAN, AYDIN, TEOMAN, ŞİMŞEK, CEREN, AKSOY, DİRENÇ ÖZLEM, BİLGİN, SABRİYE ŞENNUR, ERİŞ, ALİ HİKMET, KIZILTAN, HURİYE ŞENAY, KABLAN, ÖZGÜR, TEKÇE, ERTUĞRUL, ALTINOK SÜT, PELİN, MAYADAĞLI, ALPASLAN, AYDIN, TEOMAN, AKSOY, DİRENÇ ÖZLEM

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PublicationOpen Access

Dosimetric comparison of modern radiotherapy techniques for gastric cancer after total gastrectomy.

2020-12-01T00:00:00Z, Altinok, Pelin, Tekçe, ERTUĞRUL, Karaköse, Fatih, Berk, Kemal, Kalafat, Ümmühan, Kiziltan, Huriye Senay, Akgün, Züleyha, Mayadagli, Alpaslan, TEKÇE, ERTUĞRUL, MAYADAĞLI, ALPASLAN