Person:
ÇAKIN, ZEYNEP EBRU

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ZEYNEP EBRU
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ÇAKIN
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Now showing 1 - 3 of 3
  • PublicationMetadata only
    Association between Consumption of Cow-s Milk and Iron Deficiency Anemia in Children: Are There Roles for Hepcidin-25/Ferroportin? A Case-Control Study
    (2020-07-01T00:00:00Z) Vehapoglu, Aysel; Ozgurhan, Gamze; USTABAŞ KAHRAMAN, Feyza; ÇAKIN, ZEYNEP EBRU; SÜMBÜL, BİLGE; VEHAPOĞLU TÜRKMEN, AYSEL; USTABAŞ KAHRAMAN, FEYZA; ÇAKIN, ZEYNEP EBRU; SÜMBÜL, BİLGE
    Systemic iron homeostasis is regulated by the interaction of the peptide hormone, hepcidin and the iron exporter, ferroportin. The objective was to investigate the relationship between the consumption of cow-s milk and iron deficiency anemia in children 2-10 years old and its association with the hepcidin-25 and ferroportin concentrations. The study population consisted of 187 prepubescent children of similar ideal body weight (IBW:90-120%); 82 children with iron deficiency anemia (37girls and 45boys; 4.27 +/- 0.28 years) and 105 (47girls and 58boys; 4.25 +/- 0.34 years) healthy age-sex-matched controls. Serum fasting hepcidin-25/ferroportin concentrations were measured by enzyme immunoassay in all subjects. Mean cow-s milk consumption in the anemic group (373 +/- 248 mL/d) tended to be higher than that in the control group (320 +/- 226 mL/d), but the result was not statistically significant (p = 0.063).The mean hepcidin-25 level was significantly higher in the anemic group (19.5 +/- 18.4 ng/mL) than in the healthy controls (11.0 +/- 10.7, p < 0.001). The mean ferroportin level was lower in the anemic group (21.04 +/- 5.74 ng/mL) than in the healthy controls (22.68 +/- 4.77 ng/ml, p = 0.037). Consuming cow-s milk was not associated with IDA in prepubertal children, provided that it was adequately supplemented with iron-enriched foods. We observed a significant increase in hepcidin-25 levels and a decrease in ferroportin levels in children with iron deficiency anemia compared with healthy controls. Children who consumed more cow-s milk had higher levels of hepcidin-25. Iron deficiency anemia is not a concern when cow-s milk is given to children if the complementary foods are rich in iron.
  • PublicationMetadata only
    Is overweight/obesity a risk factor for atopic allergic disease in prepubertal children? A case-control study
    (2021-01-01T00:00:00Z) VEHAPOĞLU TÜRKMEN, Aysel; ÇAKIN, ZEYNEP EBRU; USTABAŞ KAHRAMAN, Feyza; NURSOY, MUSTAFA ATİLLA; TOPRAK, ALİ; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIN, ZEYNEP EBRU; USTABAŞ KAHRAMAN, FEYZA; NURSOY, MUSTAFA ATİLLA; TOPRAK, ALİ
    Objectives: It is unclear whether body weight status (underweight/normal weight/overweight/obese) is associated with allergic disease. Our objective was to investigate the relationship between body weight status (body mass index; BMI) and atopic allergic disease in prepubertal children, and to compare children with atopic allergic diseases with non atopic healthy children.
  • PublicationMetadata only
    aspirasyon sendromları
    (selen yayıncılık, 2022-06-01) Çakın Z. E.; Çakır E.; ÇAKIN, ZEYNEP EBRU; ÇAKIR, ERKAN