Person:
ÇAY, ALI

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ALI
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ÇAY
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Now showing 1 - 7 of 7
  • PublicationOpen Access
    Does ozone administration have a protective or therapeutic effect against radiotherapy-induced testicular injury?
    (2019-03-01) AYDOĞDU, İBRAHİM; İLBEY, YUSUF ÖZLEM; ÇOBAN, GANİME; EKİN, RAHMİ GÖKHAN; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALİ; KIZILTAN, HURİYE ŞENAY; EKİN, ZÜBEYDE YILDIRIM; SILAY, MESRUR SELÇUK; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALI; KIZILTAN, HURİYE ŞENAY
    Objective: We investigate the protective and therapeutic effects of ozone therapy (OT) in radiotherapy (RT)‑induced testicular damage. Methods: Thirty healthy adult male Wistar rats divided into five groups consisting of six animals each as follows: (1) Control (C), (2) RT, (3) OT, (4) OT + RT, and (5) RT + OT group. Histopathological findings, Johnsen scores, thiobarbituric acid‑reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) levels were evaluated. Results: RT caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase, and GPx levels were significantly lower in the RT group when compared to the control group. Pre and postRT OT significantly increased GSH, SOD, catalase, and GPx levels and decreased TBARS level. Furthermore, testicular weight and Johnsen score were increased with OT. Conclusions: The present study showed that OT is protective and therapeutic in radiation‑induced testicular damage. OT may be beneficial to the patients who underwent RT.
  • PublicationMetadata only
    Prenatal ultrasound findings and a new ultrasonographic sign of epidermolysis bullosa with congenital pyloric atresia: a report of three cases
    (2014-10-07T00:00:00Z) DURAL, Ozlem; ACAR, Deniz K.; EKIZ, Ali; ASLAN, Halil; POLAT, İbrahim; YILDIRIM, Gokhan; GULAC, Bekir; ERDEMOGLU, Yeliz; Cay, ALİ; HACıHASANOGLU, Osman; ÇAY, ALI
  • PublicationMetadata only
    Effects of carbon dioxide pneumoperitoneum on exocrine and endocrine functions, and oxidative state of rat pancreas
    (2020-07-01T00:00:00Z) Sag, Sefa; İMAMOĞLU, MUSTAFA; SARIHAN, HALUK; YULUĞ, ESİN; ALVER, AHMET; GEZE SAATÇI, ŞÜKRAN; ÇAY, Ali; ÇAY, ALI
    We investigated the effects of increased intra-abdominal pressure during laparoscopy on the endocrine and exocrine functions, oxidative stress and histopathology of the pancreas in rats. We established three experimental groups of eight animals. Group 1 was the untreated control. Forth other two groups, pneumoperitoneum with CO(2)was established for 60 min at 6 mm Hg for group 2 and 12 mm Hg for group 3; groups 2 and 3 animals were allowed to re-perfuse for 30 min. Amylase, glucagon and insulin levels were analyzed in blood samples and insulin:glucagon ratio was calculated. Histopathology and malondialdehyde assay were performed on pancreatic tissue samples. Histological damage scores for vasocongestion were increased significantly in groups 2 and 3 compared to group 1. Histological damage scores for inflammatory cell infiltration were increased significantly in group 3 compared to group 1. Malondialdehyde levels were increased significantly in group 3 compared to group 1. We found no significant differences among groups for serum amylase levels or histological damage scores for hemorrhage. Insulin and glucagon levels, and the insulin:glucagon ratio was increased significantly in group 3 compared to groups 1 and 2. We found that in rats routine laparoscopy caused increased serum insulin and glucagon levels, and histopathological changes that indicated ischemia-reperfusion injury to the pancreas.
  • PublicationOpen Access
    Prenatal diagnosis of mediastinal neurenteric cyst: a case report and review of the literature
    (2018-10-01) Cay, ALİ; Aydogdu, Ibrahim; Mirapoglu, Semih Lutfu; Toprak, HÜSEYİN; ÇAY, ALI; AYDOĞDU, İBRAHİM; TOPRAK, HÜSEYİN
    Neurenteric cyst is a very rare developmental anomaly. Prenatal diagnosis of mediastinal neurenteric cysts has been reported rarely. We present a case of neurenteric cyst associated with vertebral anomalies diagnosed by prenatal ultrasonography at 31 weeks of gestation, which was treated successfully in the early neonatal period. In addition, we searched the English literature for all cases of mediastinal neurenteric cyst diagnosed in the prenatal period reported to date. We found that only 17 cases were reported previously. We reviewed the reports of these 17 patients along with our case, and we investigated the prenatal and postnatal diagnosis and treatment approaches and the factors influencing the prognosis. Fetuses with mediastinal neurenteric cysts should be monitored regularly by ultrasonography. Fetuses with no signs of hydrops are more likely to survive with proper neonatal center transfer, regular follow-up, and appropriate postnatal approach. Fetuses with hydrops findings have a high risk of fetal and neonatal death.
  • PublicationMetadata only
    Does ozone administration have a protective or therapeutic effect against radiotherapy-induced testicular injury
    (2019-03-01T00:00:00Z) Aydogdu, Ibrahim; Ilbey, YUSUF ÖZLEM; ÇOBAN, GANİME; Ekin, Rahmi Gokhan; Mirapoglu, Semih Lutfi; Cay, Ali; Kiziltan, Huriye Senay; Ekin, Zubeyde Yildirim; Silay, Mesrur Selcuk; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; İLBEY, YUSUF ÖZLEM; ÇOBAN, GANİME; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALI; KIZILTAN, HURİYE ŞENAY
    Objective: We investigate the protective and therapeutic effects of ozone therapy (OT) in radiotherapy (RT)-induced testicular damage. Methods: Thirty healthy adult male Wistar rats divided into five groups consisting of six animals each as follows: (1) Control (C), (2) RT, (3) OT, (4) OT + RT, and (5) RT + OT group. Histopathological findings, Johnsen scores, thiobarbituric acid-reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) levels were evaluated. Results: RT caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase, and GPx levels were significantly lower in the RT group when compared to the control group. Pre and postRT OT significantly increased GSH, SOD, catalase, and GPx levels and decreased TBARS level. Furthermore, testicular weight and Johnsen score were increased with OT. Conclusions: The present study showed that OT is protective and therapeutic in radiation-induced testicular damage. OT may be beneficial to the patients who underwent RT.
  • PublicationMetadata only
    IRF4 Positivity is a Novel Diagnostic and Prognostic Marker for Diffuse Large B Cell Lymphoma
    (2018-11-01T00:00:00Z) GÜLER, Beril; ÇAKIR, FATMA BETÜL; Cay, A.; Mirapoglu, S.; Turkmen, A. Vehaboglu; Aki, H.; ÇAKIR, FATMA BETÜL; GÜLER, BERIL; ÇAY, ALI
  • PublicationMetadata only
    Does ozone administration have a protective effect against cisplatin-induced histological changes in rat testis?
    (2017-01-01) Aydogdu, Ibrahim; EKIN, Rahmi G.; Yildiz, PELİN; MIRAPOGLU, Semih L.; Cay, ALİ; KILINCASLAN, Huseyin; SEMERCİ, MEHMET BÜLENT; ILBEY, Yusuf O.; AYDOĞDU, İBRAHİM; ÇAY, ALI