Person: ŞENOL, HALIL
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Publication Metadata only Synthesis of New Oleanane Triterpenoids Including Fatty Acids Esters and Investigation of Their in vitro Cytotoxic Effects on 3T3 Fibroblast and PC3 Prostate Cancer Cell Lines(2019-12-19) Dağ, Aydan; Topçu, Gülaçtı; Atasoy, Sezen; Aktaş, Asude Sena; Şenol, Halil; ŞENOL, HALIL; DAĞ, AYDAN; ATASOY, SEZEN; TOPÇU, GÜLAÇTIPublication Metadata only Ursolik Asit ve Oleanolik Asitten Hareketle alfa-Amirin ve beta-Amirin Sentezi için Yeni ve Etkin Bir Yöntem(2017-04-29) SEÇEN, HASAN; ŞENOL, HALİL; TOPÇU, GÜLAÇTI; TUNCAY, SALİH; ÖCAL, NÜKET; ŞENOL, HALIL; TOPÇU, GÜLAÇTIPublication Metadata only Oleanolik Asit Türevlerinin Sentezi ve Sitotoksik Aktivitelerinin Araştırılması(2017-04-02) TUNCAY, SALİH; ŞENOL, HALİL; GÜLER, ERAY METİN; ÖCAL, NÜKET; SEÇEN, HASAN; KOÇYİĞİT, ABDÜRRAHİM; TOPÇU, GÜLAÇTI; ŞENOL, HALIL; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; TOPÇU, GÜLAÇTIPublication Metadata only Effect of Lipids in Tissue Factor Activity Isolated From Sheep and Lamb Lung(2017-05-25) TENEKECİGİL, ASLIHAN; ŞENOL, HALİL; ŞENOL, AYŞE MERVE; EMEKLİ, NESRİN; ŞENOL, HALILPublication Metadata only Bazı Uvaol Türevlerinin Sentezi ve in vitro Biyoaktivitelerininİncelenmesi(2017-04-29) Tuncay, Salih; Öcal, Nüket; Seçen, Hasan; Şenol, Halil; Güler, Eray Metin; Topçu, Gülaçtı; Koçyiğit, Abdürrahim; Akdemir, Atilla; ŞENOL, HALIL; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; TOPÇU, GÜLAÇTIPublication Metadata only Nükleer Faktör Kappa-B İnhibisyon Etkili Ursan Türevi Triterpenlerin Sentezi(2017-04-02) TUNCAY, SALİH; SEÇEN, HASAN; ÖCAL, NÜKET; TOPÇU, GÜLAÇTI; AKDEMİR, ATİLLA; ŞENOL, HALİL; ŞENOL, HALIL; AKDEMİR, ATİLLA; TOPÇU, GÜLAÇTIPublication Metadata only Synthesis and rearrangement reactions of 1,4-dihydrospiro[1,4-methanonaphthalene-9,1′-cyclopropane] derivatives(2018-10-04T00:00:00Z) Bayrak, Cetin; Senol, Halil; Sirtbasi, Sedef; Şahin, Ertan; Menzek, Abdullah; ŞENOL, HALILPublication Metadata only Synthesis of New 4-Thiazolidinone Derivatives and Investigation of their in vitro Cytotoxic Effects on Breast Cancer(2019-12-19) Şenol, Halil; Atasoy, Sezen; Güzeldemirci, Nuray; ŞENOL, HALIL; ATASOY, SEZENPublication Metadata only Computer Aided Design and Synthesis of New Ursane Triterpenoids with Nuclear Factor Kappa B Inhibition Effect(2019-12-19) Şenol, Halil; Akdemir, Atilla; Topçu, Gülaçtı; ŞENOL, HALIL; AKDEMİR, ATİLLA; TOPÇU, GÜLAÇTIPublication Metadata only Synthesis of Oleanolic Acid Analogues and Their Cytotoxic Effects on 3T3 Cell Line(2018-01-01) Tuncay, Salih; Kocyigit, ABDÜRRAHİM; SEÇEN, Hasan; Ocal, Nuket; Topcu, GÜLAÇTI; Guler, ERAY METİN; ŞENOL, HALIL; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; TOPÇU, GÜLAÇTIBackground: Oleanolic acid (OA) is a known natural compound with many important biological activities. Thirteen oleanolic acid derivatives linked at C-3 and C-28 were synthesized and their structures were confirmed by H-1- and C-13 NMR and mass spectral analyses. Among them, compounds 4, 6, 8-10, 12, 13 were synthesized for the first time. They were evaluated for their cytotoxic activity. They showed proliferative effect at low concentrations while cytotoxic effect was observed at high concentrations in a dose dependent manner.