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COŞKUN, HALIL

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HALIL
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COŞKUN
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  • PublicationMetadata only
    The effects of different mechanisms on the development of post-ERCP pancreatitis in an ERCP model in rats
    (2013-12-01T00:00:00Z) Bozkurt, SÜLEYMAN; GUNER, Ali; Kadioglu, HÜSEYİN; KECE, Can; REIS, Erhan; COSKUN, HALİL; BOZKURT, SÜLEYMAN; KADIOĞLU, HÜSEYİN; COŞKUN, HALIL
    Background/aims: To investigate the effects of different mechanisms on the development of pancreatitis after endoscopic retrograde cholangiopancreatography. Material and Methods: 40 male rats were randomly divided into four groups. After laparotomy, in Group 1, only duodenum was reached by a 24G cannula without performing any other procedure. In Groups 2, 3, and 4, biliopancreatic duct was cannulated transduodenally. Group 2 received no additional intervention after the cannulation. Group 3 received saline, whereas Group 4 received contrast agent into the duct. After a period of 24 hours, all rats were sacrificed. Laboratory tests for blood samples were performed and pancreatic tissue was also evaluated histopathologically. Results: Leukocyte, blood sugar, serum glutamic oxaloacetic transaminase, lactate dehydrogenase, amylase, C-reactive protein, and base excess parameters were evaluated. The values in Groups 2, 3, and 4 were found to be significantly higher than those in the control group, except for leukocyte count and base excess (p=0.551, p=0.031, p=0.0001, p=0.0001, p=0.0001, p=0.0001, p=0.683, respectively). Histopathological results demonstrated significant differences between the groups. Highest pathological damage scores were observed in Groups 3 and 4. Conclusion: Among different theories for the pathogenesis of post-endoscopic retrograde cholangiopancreatography pancreatitis, elevated intraductal hydrostatic pressure was observed to be the main underlying cause.
  • PublicationOpen Access
    Remission of ulcerated necrobiosis lipoidica diabeticorum after bariatric surgery.
    (2013-01-01) BOZKURT, SÜLEYMAN; COSKUN, HALİL; Kadioglu, HÜSEYİN; MEMMI, NAİM; CIPE, G; ERSOY, YELİZ EMİNE; LEBE, B; MUSLUMANOGLU, M; BOZKURT, SÜLEYMAN; COŞKUN, HALIL; KADIOĞLU, HÜSEYİN; MEMMİ, NAİM; ERSOY, YELIZ EMINE
    A 32-year-old woman with type 2 diabetes mellitus suffering from morbid obesity with BMI 45,14 kg/m2 was operated on. Not only the type 2DM but also one of its complication known as necrobiosis lipoidica diabeticorum remitted postoperatively. Obesity should no longer be regarded simply as a cosmetic problem affecting certain individuals but an epidemic that threatens global well-being. It causes or exacerbates many health problems, and in particular, it is associated with the type 2 diabetes. Necrobiosis lipoidica is a granulomatous skin disease of unknown etiology, associated mainly with diabetes mellitus. We presented in this paper a morbid obese case of necrobiosis lipoidica diabeticorum with dramatic good response to bariatric surgery.
  • PublicationOpen Access
    Single Incision Laparoscopic Cholecystectomy in situs Inversus Totalis.
    (2012-07-01T00:00:00Z) BOZKURT, SÜLEYMAN; COSKUN, HALİL; ATAK, T; Kadioglu, HÜSEYİN; BOZKURT, SÜLEYMAN; COŞKUN, HALIL; KADIOĞLU, HÜSEYİN