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KOLUKISA, MEHMET

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MEHMET
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Now showing 1 - 9 of 9
  • PublicationMetadata only
    Evaluation of cerebral hemodynamic status in patients with unilateral symptomatic carotid artery stenosis during motor tasks, through use of transcranial Doppler sonography
    (2022-04-01T00:00:00Z) Milanlıoğlu, Aysel; YAMAN KULA, ASLI; KOLUKISA, MEHMET; ASİL, Talip; YAMAN KULA, ASLI; KOLUKISA, MEHMET; ASİL, TALIP
    Background: Carotid artery stenosis increases cerebral ischemic event risk through changing different cerebral hemodynamic parameters. Objective: To investigate how cerebral hemodynamics in the M1 segment of middle cerebral artery change in patients with carotid artery stenosis, after motor tasks using transcranial Doppler sonography (TCD). Methods: Thirty-two healthy subjects and 30 patients with unilateral symptomatic carotid artery stenosis were recruited. The patient population was divided into three groups according to the degree of stenosis (group 1: ≥50 to 69%, group 2: 70 to 89% and group 3: ≥90 to 99%). TCD was used to measure the pulsatility index (PI) and cerebral vasomotor reactivity (CVR). Results: In the patient group, significant differences for symptomatic side PI values (p=0.01) and mean CVR increases (p=0.05) were observed, compared with the healthy controls. However, the difference was not statistically significant for asymptomatic side PI values and mean CVR increases. The results from the intergroup comparison showed significantly higher percentages of symptomatic and asymptomatic side CVR increases in group 1, compared with groups 2 and 3 (p=0.001 and p=0.002, respectively). Conclusions: Our study showed that cerebral autoregulation and hemodynamic mechanisms are impaired in patients with carotid artery stenosis. Furthermore, the impairment of PI and CVR tends to get worse with increasing degrees of stenosis. In addition, this study demonstrated that assessment of these two hemodynamic parameters in clinical practice might be helpful for monitoring the progress of carotid artery stenosis.
  • PublicationOpen Access
    Endovascular Therapy of Acute Ischemic Stroke by Interventional Cardiologists: National Initial Experience
    (2013-10-29) TASAL, Abdurrahman; Bacaksiz, AHMET; VATANKULU, Mehmet Akif; SONMEZ, Osman; TURFAN, Murat; ERDOGAN, Ercan; KARADELI, Hasan Huseyin; Kolukisa, MEHMET; KUL, Seref; ALTINTAS, Ozge; Asil, TALİP; GOKTEKIN, Omer; BACAKSIZ, AHMET; KOLUKISA, MEHMET; ASİL, TALIP
    Objectives: We report our initial experience with thrombectomy devices in patients with acute ischemic stroke. Study design: Demographic, clinical, and angiographic findings of 19 consecutive patients (7 females and 12 males; mean age 61.4±12.5 years) with acute ischemic stroke were evaluated retrospectively. Results: The mean initial National Institutes of Health Stroke Scale (NIHSS) score was 19.5±5.6. Middle cerebral artery was the occluded artery in all of the patients (proximal occlusion in 11, distal in 8 and tandem occlusions in 7 patients). Successful revascularization was achieved in 16 patients (84%). The mean NIHSS score was 8.4±8.2 at 24 hours after the procedure, and 60% of patients showed a modified Rankin scale score of ≤2 at 90 days. New occlusion by migrated emboli was observed in 2 (11%) cases. None of the patients had experienced post-procedural symptomatic intracerebral hemorrhage; 3 patients died during the three-month follow-up. In all patients, thrombectomy was performed with retrievable Solitaire AB stent system. Conclusion: This single-center experience with mechanical thrombectomy devices demonstrated that high success rates can be achieved by experienced interventional cardiologists in equipped cath labs throughout the country.
  • PublicationOpen Access
    One-year follow-up in patients with brainstem infarction due to large-artery atherothrombosis
    (2015-01-01) Kolukisa, MEHMET; GUELTEKIN, Tugce Ozdemir; BARAN, Gozde Eryigit; Aralasmak, AYŞE; KOCAMAN, Guelsen; GUERSOY, Azize Esra; Asil, TALİP; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; GÜRSOY, AZIZE ESRA; ASİL, TALIP
    Background: Posterior circulation infarction accounts for approximately 25% of the ischemic strokes. A number of different conditions may be associated with the development of brainstem infarction. Prognosis and recurrence rate of brainstem infarction due to large-artery atherothrombosis is still controversial. Methods: A total of 826 patients with ischemic stroke were admitted to our clinic during a 15-month period. Patients with clinical and radiological evidence of brainstem infarction were comprehensively assessed with appropriate vascular imaging modalities and for cardiological causes. Subjects with an established diagnosis of large-artery atherothrombosis were followed up for 1 year in terms of prognosis and recurrence rates. Results: Of the 101 patients with an established brainstem infarction, the diagnostic work-up indicated the presence of large-artery atherothrombosis as the causative factor in 53. A recurrent stroke was detected in the posterior circulation within the first 3 months in 5.8% and within 1 year in 9.8% of these individuals. The 1-year mortality rate was 11.7%. All patients with recurrent stroke had intracranial vascular narrowing at baseline. Conclusion: Our findings demonstrate a particularly high rate of recurrence and mortality at 1 year among patients who have a brainstem infarction due to intracranial arterial stenosis. Keywords: posterior circulation, intracranial arteries, extracranial arteries, stroke, vertebral artery, basilar artery
  • PublicationMetadata only
    Endovascular therapy of acute ischaemic stroke by interventional cardiologists: single-centre experience from Turkey
    (2014-11-01) GOKTEKIN, Omer; TASAL, Abdurrahman; UYAREL, Huseyin; VATANKULU, Mehmet Akif; SONMEZ, Osman; AY, Nuray; KUL, Seref; YAMAC, Hatice; ALTINTAS, Ozge; KARADELI, Hasan; Kolukisa, MEHMET; Aralasmak, AYŞE; Asil, TALİP; KAHRAMAN AY, NURAY; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; ASİL, TALIP
    Aims: We report our single-centre experience with the Solitaire AB self-expanding retrievable stent system in patients with acute ischaemic stroke.
  • PublicationMetadata only
    CREUTZFELDT-JAKOB DISEASE: A SINGLE CENTER EXPERIENCE AND SYSTEMIC ANALYSIS OF CASES IN TURKEY
    (2020-05-01T00:00:00Z) Uslu, Ferda; Gokcal, Elif; GÜRSOY, Azize Esra; KOLUKISA, MEHMET; Yildiz, Gulsen Babacan; USLU, FERDA; GÖKÇAL, ELİF; GÜRSOY, AZIZE ESRA; KOLUKISA, MEHMET
    Introduction - We aimed to analyze the clinical, laboratory and neuroimaging findings in patients with sporadic Creutzfeldt-Jakob disease (CJD) in a single center as well as to review other published cases in Turkey.
  • PublicationOpen Access
    Relationship between electrodiagnostic severity and neuropathic pain assessed by the LANSS pain scale in carpal tunnel syndrome.
    (2013-01-01T00:00:00Z) KOLUKISA, MEHMET; Gürsoy, AZİZE ESRA; YıLDıZ, GB; KOCAMAN, G; CELEBI, A; KOÇER, A; GÜRSOY, AZIZE ESRA; KOLUKISA, MEHMET; BABACAN YILDIZ, GÜLSEN
    Objective: The aim of the study was to investigate the relationship between the presence of neuropathic pain assessed by the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale and electrophysiological findings in patients with carpal tunnel syndrome (CTS). Methods: We studied 124 hands with idiopathic CTS with pain complaints involving hand and wrist. All hands were assessed by the LANSS with which a score of 12 or more is defined as pain dominated by neuropathic mechanisms. These hands were assigned to minimal, mild, moderate, severe, or extreme severe groups according to the results of the median nerve conduction studies. Results: A LANSS score $ 12, suggestive of pain dominated by neuropathic mechanisms, was defined in 59 (47.6%) CTS hands. Pain intensity was significantly higher in CTS hands with a LANSS score $ 12 (P , 0.001). Among electrophysiological findings, compound muscle action potential amplitude was significantly lower in hands with a LANSS score $ 12 compared with hands with a LANSS score , 12 (P = 0.020). Severity of CTS was not significantly different between LANSS $ 12 and LANSS , 12 groups. Electrophysiological severity was significantly higher in CTS hands with evoked pain (P = 0.005) and allodynia (P , 0.001) in LANSS subscore analysis. Conclusion: We suggest that the presence of pain dominated by neuropathic mechanisms in CTS is not related to electrophysiological CTS severity. Neuropathic pain should be assessed carefully in patients with CTS, and an appropriate treatment plan should be chosen, taking into account the clinical and electrophysiological findings together with the true pain classification. Keywords: electrodiagnostic evaluation, carpal tunnel syndrome, LANSS, neuropathic pain
  • PublicationOpen Access
    Craniocervical Dissections: Radiologic Findings, Pitfalls, Mimicking Diseases: A Pictorial Review
    (2018-01-01) MEHDI, Elnur; Aralasmak, AYŞE; Toprak, HÜSEYİN; Yildiz, Seyma; Kurtcan, SERPİL; Kolukisa, MEHMET; Asil, TALİP; Alkan, ALPAY; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; YILDIZ, ŞEYMA; KURTCAN, SERPİL; KOLUKISA, MEHMET; ASİL, TALIP; ALKAN, ALPAY
    Background: Craniocervical Dissections (CCD) are a crucial emergency state causing 20% of strokes in patients under the age of 45. Although DSA (digital substraction angiography) is regarded as the gold standard, noninvasive methods of CT, CTA and MRI, MRA are widely used for diagnosis. Aim: Our aim is to illustrate noninvasive imaging findings in CCD. Conclusion: Emphasizing on diagnostic pitfalls, limitations and mimicking diseases.
  • PublicationMetadata only
    Idiopathic spinal accessory nerve palsy: A case report and review of the literature.
    (2013-01-01T00:00:00Z) Gürsoy, AZİZE ESRA; BABACAN-YıLDıZ, G; KOLUKıSA, MEHMET; CELEBI, A; GÜRSOY, AZIZE ESRA; BABACAN YILDIZ, GÜLSEN; KOLUKISA, MEHMET
  • PublicationOpen Access
    Bilateral Thalamic Infarction
    (2015-04-01) HALAÇ, Gülistan; Tektürk, Pınar; Deniz, Çiğdem; Kolukısa, Mehmet; OZCAN, Muhammet Emin; Asil, Talip; DENİZ, ÇİĞDEM; KOLUKISA, MEHMET; ASİL, TALIP
    Bilateral thalamic infarction is a rare cerebral vascular disease. The most common findings are acute impairment of consciousness, vertical gaze paresis, cognitive disturbances, and abnormal behavioral symptoms. In this paper, we report a case of bilateral thalamic infarction that resulted in abnormal behavior.