Person: KIRPINAR, İSMET
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- PublicationMetadata onlyThe psychiatric assessment schedule for adults with developmental disability checklist: reliability and validity of Turkish version(2017-01-01) GORMEZ, Aynur; Kirpinar, Ismet; KIRPINAR, İSMETAim/background: There is a lack of psychometric instruments to measure psychopathology in people with intellectual disabilities (ID). This may lead to underdiagnosis of treatable psychiatric comorbidities in this population. Psychiatric assessment schedule for adults with developmental disabilities (PAS-ADD) Checklist was developed as a screening tool designed for lay people. The PAS-ADD Checklist was created in English and was later on validated for other languages, including French and German. There is no psychometric measure available in Turkish to screen for or detect psychiatric symptoms in adults with ID. The aim of the present study was to present a psychometric evidence of the Turkish language version of the PAS-ADD Checklist. This is the first study aiming to present and validate a psychiatric screening instrument for adults with ID in Turkey.
- PublicationMetadata onlyRole of Lymphocyte Subsets and T-Cell Profiles in the Immune Dysfunction of Schizophrenia(2018-05-01) SAHBAZ, Cigdem; Zibandeyeh, Noushin; Kurtulmus, AYŞE; AVAROGLU, Gamze; Kirpinar, Ismet; Sahin, Fikrettin; AKKOÇ, TUNÇ; ŞAHBAZ, ÇIĞDEM DILEK; KURTULMUŞ, AYŞE; KIRPINAR, İSMET
- PublicationMetadata onlyPsychiatric disorders in adults with mental retardation: prevalence and associated factors(2017-08-01) GÖRMEZ, AYNUR; Kirpinar, Ismet; KIRPINAR, İSMETObjective: Mental retardation (MR) is a spectrum of disorders characterized by deficits in intellectual and adaptive functioning which could result from several different etiological factors. Studies have shown that people with MR develop mental illness at rates similar to or higher than general population. We have not found any previous study carried out on adults with MR in Turkey. The aim of this study to determine the prevalence of mental disorders in Turkish population and to investigate associated factors. Methods: Participants aged 18 years and above and with a confirmed diagnosis of were recruited from care homes, rehabilitation centers and from people attending to outpatients for the first time for psychiatric assessment. A structured purpose designed Sociodemographic Form was used. Each participant underwent face to face assessment by a psychiatrist and their previous reports were also seen where available. Collateral history was provided by their families or caregivers who had known the person for at least 6 months. Diagnoses were established according to the DSM-5 criteria. Point prevalence of disorders were calculated and associated factors were investigated. Results: 63.5% of the participants met the criteria for one psychiatric disorder, whilst 21% received more than one diagnoses. The most common disorders were as follows: challenging behavior (34%), autism spectrum disorders (13.9%), anxiety-related disorders (13.9%) and attention deficit hyperactivity disorder (10.6%). Living in a care home and being young seemed to be associated with ill mental health. Conclusion: Our study demonstrates high psychiatric comorbidity in adults with MR. Young age and being in a care home seemed to be the only risk factors in our sample. These results highlight a need for increased awareness of mental health professionals and service providers about mental health of adults with MR for early diagnosis and interventions.
- PublicationMetadata onlyPrevalence of orthorexia among medical students in Erzurum, Turkey(2010-01-01T00:00:00Z) Fidan, Tulin; Ertekin, Vildan; Isikay, Sedat; Kirpinar, Ismet; KIRPINAR, İSMETOrthorevia is a new term about eating behavior disorder and consists of pathologic obsession for biologically pure foods, flee of herbicides, pesticides, and other artificial substances It is not an independent diagnostic category, but It has some similarities with other eating disorders. This study was conducted to examine the orthorexia among 878 medical students Of 878 students, 464 (52 8%) were male and 359 (40 9%) were female The mean age, height, weight. and body mass index were 21 3 2 1 years, 171 0 8 5 cm, 65 6 12 3 kg, 22 4 +/- 2 99. respectively The rates of the ORTO-11 scores between 0 and 15 was I 9%, between 16 and 30. 57 5%, and between 31 and higher, 21 1% There were 17 students with a score of 0 to 15 The mean score for the ORTO-11 test was 27 There were statistically significant differences between age, sex, and smoking habit of the students In the male students, there was a statistically significantly higher tendency for orthorexia (P = 001), and there was a statistically significant difference between the age groups for tendency lot orthorexia = 025) In logistic regression analysis, age, sex, Eating Attitude Test-40 (EAT-40), and height affected the ORTO-11 scores Crown Copyright (C) 2010 Published by Elsevier Inc All rights reserved
- PublicationMetadata onlyTemperament and Character Traits in Patients With Epilepsy Epileptic Personality(2013-05-01) YAZICI, Esra; YAZICI, Ahmet Bulent; Aydin, Nazan; Orhan, Asuman; Kirpinar, Ismet; Acemoglu, Hamit; KIRPINAR, İSMETPersonality and behavioral changes in epilepsy are well documented. However, neither the quantitative characteristics nor the etiology of these changes is clear yet. Cloninger has developed a psychobiological personality model that provides a way to evaluate personality in a dimensional way. This study examined the relationship between epilepsy and Cloninger-s dimensional psychobiological personality model. A total of 73 epilepsy outpatients and 79 healthy controls were examined using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I Disorders, the Turkish version of the Temperament and Character Inventory, and an epilepsy questionnaire. Epilepsy patients had higher harm avoidance ( HA) and lower persistence, self-directedness (SD), and cooperativeness scores than healthy controls did. In epileptic subjects, there was no correlation between age and duration of epilepsy. Subjects with partial seizures had higher HA scores and lower SD scores than generalized ones. Comorbid depression was represented with lower SD scores. In multiple linear regression models, only major depressive disorder predicted lower scores of SD. This study confirms specific personality changes among epileptics according to Cloninger-s dimensional personality model and indicates a relationship between the characteristics of epilepsy and psychiatric comorbidity.
- PublicationMetadata onlyMale Genital Self-mutilation as a Psychotic SolutionOzan, Erol; Deveci, Erdem; ORAL, Meltem; Yazici, Esra; Kirpinar, Ismet; DEVECİ, ERDEM; KIRPINAR, İSMETBackground: Male genital self-mutilation (GSM) is a rare, but serious phenomenon. Some of the risk factors for this act are: presence of religious delusions, command hallucinations, low self-esteem and feelings of guilt associated with sexual offences. Other risk factors include failures in the male role, problems in the early developmental period, such as experiencing difficulties in male identification and persistence of incestuous desires; depression and having a history of GSM. The eponym Klingsor Syndrome, which involves the presence of religious delusions, is proposed for GSM.
- PublicationMetadata onlyNeuropsychiatric disorders and risk factors in carbon monoxide intoxication(2011-06-01T00:00:00Z) KATIRCI, Yavuz; Kandis, Hayati; Aslan, Sahin; Kirpinar, Ismet; KIRPINAR, İSMETNeuropsychiatric sequelae may be observed in the late phases of carbon monoxide (CO) intoxication. Establishing a link between CO-related neuropsychiatric disorders and associated risk factors may decrease morbidity and mortality by means of appropriate treatment and counseling. The aim of the present study was to determine the relationship between neuropsychiatric outcomes of CO intoxication and demographic and clinical variables. Thirty patients who presented with CO intoxication and had no known neuropsychiatric disease, and 30 healthy controls were included. Physical examinations and laboratory tests were performed. Following the 1st therapy, they underwent mental and psychiatric tests 5 times (the time of discharge, during the 1st week, and during the 1st, 3rd, and 6th months). They underwent cerebral magnetic resonance imaging (MRI) at the end of the 1st month. They were evaluated by cognitive function tests at the 6th month. Lesions relevant to CO intoxication were detected in 46.7% of the patients via cranial computed tomography and in 13.3% via MRI. Evaluation of psychiatric tests revealed a clear decrease in cognitive functions, such as immediate memory, learning, reaching the criterion, spontaneous recall, attention, visual memory, and logical memory. It was found that the patients had anxiety within the 1st month, and the frequency of anxiety reached to the value of the control group by the end of the 6th month. In conclusion, we suggested that CO intoxication might lead to neuropsychiatric disorders. Our results emphasized that in addition to standard treatment, neuropsychiatric evaluation should also be performed in patients with CO intoxication.
- PublicationOpen AccessAssessing and Managing Delirium in Surgical and Internal Medicine: an Overview(2016-12-01) Kirpinar, Ismet; KIRPINAR, İSMETDelirium is most common neuropsychiatric disorder that affects patients in surgical and internal medicine clinics. It is defined as a transient, usually reversible organic mental disorder that has a rapid onset and fluctuating course. Clinically, delirium is an acute or subacute organic mental syndrome that is characterized by a disturbance in attention (reduced ability to direct, focus, sustain, and shift attention), awareness (reduced orientation to the environment), and other cognitive abilities (e.g., memory deficit and disorientation) and is not better explained by preexisting, established, or other evolving neurocognitive disorders. Studies have found that between 10% and 20% of all adult inpatients are diagnosed with delirium and that it occurs in up to 50% of elderly inpatients. Delirium itself is not a disease but rather a clinical syndrome, which results from an underlying disease. There is evidence from the history, physical examination, or laboratory findings that the disturbance is a physiological consequence of an underlying medical condition, substance intoxication or withdrawal, use of a medication, or a toxin exposure, or it is a combination of these factors. Accurate identification of underlying causes and risk factors is essential in early stage diagnosis and treatment. Treatment of delirium requires the treatment of the underlying causes. Psychotropic medications are used to comfort patients or enable better patient management. This study aims to review the clinical characteristics, etiological and risk factors, and different methods to obtain an accurate diagnosis and treatment of delirium.
- PublicationMetadata onlyThe relationship between nine types temperament model with psychobiological personality model and affective temperament model(2015-04-01) YILMAZ, Enver Demirel; GENCER, Gorkem; UNAL, Ozge; OREK, Alp; Aydemir, Omer; Deveci, ERDEM; Kirpinar, Ismet; DEVECİ, ERDEM; KIRPINAR, İSMETObjective: This study aims to determine Nine Types Temperament Model (NTTM), which is a new temperament model, with Psychobiological Personality Model (PPM) and Affective Temperament Model (ATM) and define the possible relations between categories and dimensions and their degrees of predicting each other. Methods: The sample group consists of 206 healthy volunteers who did not receive any psychiatric treatment in their life and do not have any chronic disease. Structured Clinical Interview for DSM-IV (SCID-I), Structured Clinical Interview for DSM-III-R personality disorders (SCID-II), Temperament and Character Inventory (TCI), Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire Version (TEMPS-A) and Nine Type Temperament Scale (NTTS) were used to collect data. Results: Except for NTM3, NTM8 and NTM9 temperament categories, all NTTS categories have significant correlation with various TCI dimensions at a level r=0.40 and above. Except for NTM1, NTM5 and NTM9 temperament categories, all NTTS categories have significant correlation with various TEMPS-A categories at a level r=0.40 and above. According to the results of regression analyses, it is found that TCI dimensions and TEMPS-A categories can explain 29-63% of variance of NTTS temperament categories. Conclusion: This study indicates that although there are consistent and significant correlations between dimensions and categories of NTTS and the two scales widely used in psychiatry, there are conceptual differences between NTTM, PPM and ATM and temperament categories of NTTM have unique features.
- PublicationOpen AccessRelationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder(2014-01-01) CANPOLAT, Serpil; Kirpinar, Ismet; Deveci, ERDEM; Aksoy, Hulya; BAYRAKTUTAN, Zafer; EREN, Ibrahim; Demir, Recep; Selek, Salih; Aydin, Nazan; KIRPINAR, İSMET; DEVECİ, ERDEMAbstract We investigated the relationship of serum nitric oxide (NO) and asymmetrical dimethylarginine (ADMA) levels with cognitive functioning in patients with major depressive disorder (MDD). 41 MDD patients (Beck depression scale scores>16) and 44 controls were included in the study. Rey verbal learning and memory test, auditory consonant trigram test, digit span test, Wisconsin card sorting test, continuous performance task (TOVA), and Stroop test scores were found to be impaired in patients with major depressive disorder when compared to healthy controls. There was no significant difference between patient and control groups in terms of serum NO and ADMA. Serum NO levels were correlated with TOVA test error scores and Stroop test time scores, whereas serum ADMA levels were negatively correlated with TOVA test error scores. Metabolic detriments especially in relation to NO metabolism in frontal cortex and hypothalamus, psychomotor retardation, or loss of motivation may explain these deficits.
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