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KIRPINAR, İSMET

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İSMET
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KIRPINAR
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2013 - 20184
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Author: Kirpinar, Ismet × Author: Deveci, ERDEM × Has files: true ×

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Now showing 1 - 4 of 4
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    PublicationOpen Access
    Clozapine Treatment and Thrombocytopenia: a Case Report
    (2014-09-01) Ozturk, AHMET; Deveci, ERDEM; DURSUN, Ali Emre; Soyucok, Etem; Kirpinar, Ismet; DEVECİ, ERDEM; KIRPINAR, İSMET
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    PublicationOpen Access
    Development of Hyperprolactinemia Induced by the Addition of Bupropion to Venlafaxine XR Treatment
    (2018-04-01) KILIÇ, Alperen; Ozturk, AHMET; Deveci, ERDEM; Kirpinar, Ismet; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMET
    Hyperprolactinemia is characterized by abnormally increased serum prolactin levels. Menstrual irregularities and hyperprolactinemia can be caused by a variety of medical conditions as well as due to the use of some psychopharmacological drugs, namely antipsychotics; it can also develop during antidepressant treatment. Bupropion is an antidepressant functioning via the inhibition of noradrenaline and dopamine reuptake. The endocrine and sexual adverse events of this agent are rare. In the literature, only one case reporting hyperprolactinemia or galactorrhea caused by bupropion use is available. Here, we present the case of a patient diagnosed with depressive disorder and receiving venlafaxine, who developed hyperprolactinemia and oligomenorrhea after the addition of bupropion the ongoing treatment and showed serum prolactin levels decreased to normal ranges shortly after the discontinuation of bupropion.
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    PublicationOpen Access
    Improvement in attention and executive functions during isotretinoin treatment in patients with acne
    (2013-06-01) Deveci, ERDEM; Ozturk, AHMET; Kirpinar, Ismet; ENGIN, Ragip Ismail; MELIKOGLU, Mehmet; SAKAT, Selcen Caferoglu; DEMIR, Muhammet; CANPOLAT, Serpil; DEVECİ, ERDEM; ÖZTÜRK, AHMET; KIRPINAR, İSMET
    Background and Design: We assessed attention, memory, verbal-linguistic ability, and executive functions in acne vulgaris patients before and during isotretinoin treatment.
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    PublicationOpen Access
    Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder
    (2014-01-01) CANPOLAT, Serpil; Kirpinar, Ismet; Deveci, ERDEM; Aksoy, Hulya; BAYRAKTUTAN, Zafer; EREN, Ibrahim; Demir, Recep; Selek, Salih; Aydin, Nazan; KIRPINAR, İSMET; DEVECİ, ERDEM
    Abstract We investigated the relationship of serum nitric oxide (NO) and asymmetrical dimethylarginine (ADMA) levels with cognitive functioning in patients with major depressive disorder (MDD). 41 MDD patients (Beck depression scale scores>16) and 44 controls were included in the study. Rey verbal learning and memory test, auditory consonant trigram test, digit span test, Wisconsin card sorting test, continuous performance task (TOVA), and Stroop test scores were found to be impaired in patients with major depressive disorder when compared to healthy controls. There was no significant difference between patient and control groups in terms of serum NO and ADMA. Serum NO levels were correlated with TOVA test error scores and Stroop test time scores, whereas serum ADMA levels were negatively correlated with TOVA test error scores. Metabolic detriments especially in relation to NO metabolism in frontal cortex and hypothalamus, psychomotor retardation, or loss of motivation may explain these deficits.