Person:
KIRPINAR, İSMET

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İSMET
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KIRPINAR
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Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment

2019-01-01, ÖZTÜRK, AHMET, Şahan, Ebru, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET, ÖZTÜRK, AHMET, ŞAHAN, EBRU, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET

Objective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.

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Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions?

2019-01-01, DEVECİ, ERDEM, Kocacenk, Tuba, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET, DEVECİ, ERDEM, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET

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Development of Hyperprolactinemia Induced by the Addition of Bupropion to Venlafaxine XR Treatment

2018-04-01, KILIÇ, Alperen, Ozturk, AHMET, Deveci, ERDEM, Kirpinar, Ismet, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET

Hyperprolactinemia is characterized by abnormally increased serum prolactin levels. Menstrual irregularities and hyperprolactinemia can be caused by a variety of medical conditions as well as due to the use of some psychopharmacological drugs, namely antipsychotics; it can also develop during antidepressant treatment. Bupropion is an antidepressant functioning via the inhibition of noradrenaline and dopamine reuptake. The endocrine and sexual adverse events of this agent are rare. In the literature, only one case reporting hyperprolactinemia or galactorrhea caused by bupropion use is available. Here, we present the case of a patient diagnosed with depressive disorder and receiving venlafaxine, who developed hyperprolactinemia and oligomenorrhea after the addition of bupropion the ongoing treatment and showed serum prolactin levels decreased to normal ranges shortly after the discontinuation of bupropion.

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Neuro cognitive functioning in young high-risk offspring having a parent with bipolar I disorder

2013-01-01, Deveci, ERDEM, Ozan, Erol, Kirpinar, Ismet, ORAL, Meltem, DALOGLU, Ali Gokhan, Aydin, Nazan, Ozturk, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET, ÖZTÜRK, AHMET

Aim: To investigate attention, memory, verbal-linguistic ability, and executive functions in symptom-free young offspring having a parent with bipolar I disorder (BD1O) in comparison with healthy controls (CO).

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Şiddetli Nörolojik Belirtilerle Giden Lityum İntoksikasyonunun Sağaltımı Bir Olgu Sunumu

2014-11-30, BAKAY, BETÜL, DEVECİ, ERDEM, ZİHNİ, DEMET, DURSUN, ALİ EMRE, ÖZTÜRK, AHMET, KIRPINAR, İSMET, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET

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Mirtazapinin Neden Olduğu Halüsinasyonlar Bir olgu sunumu

2015-11-29, KILIÇ, ALPEREN, ÖZTÜRK, AHMET, YILMAZ, ONUR, KIRPINAR, İSMET, ÖZTÜRK, AHMET, YILMAZ, ONUR, KIRPINAR, İSMET

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Depersonalization Associated with Kallman s Syndrome a Case Report

2015-04-19, ÖZTÜRK, AHMET, KILIÇ, ALPEREN, DURSUN, ALİ EMRE, DEVECİ, ERDEM, KIRPINAR, İSMET, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET

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Neurocognition in Patients with Acne Vulgaris

2014-11-01, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET, KOYUNCU, AHMET, ENGİN, İSMAİL, MELİKOĞLU, MEHMET, YILMAZ, ENVER DEMİREL, KOÇER, EMEL, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET

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Comparing remitted unipolar and bipolar depressive disorder according to the clinical features

2014-12-01, SOYUÇOK, ETEM, ÖZTÜRK, AHMET, AYDIN, NAZAN, KIRPINAR, İSMET, ÖZTÜRK, AHMET, KIRPINAR, İSMET

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Bupropion induced Hyperprolactonamia: A case report. Bulletin of Clinical Psychopharmacology

2015-04-19, KIRPINAR, İSMET, Kılıç, Alperen, Öztürk, AHMET, KIRPINAR, İSMET, ÖZTÜRK, AHMET