Person: KIRPINAR, İSMET
Şiddetli Nörolojik Belirtilerle Giden Lityum İntoksikasyonunun Sağaltımı Bir Olgu Sunumu
2014-11-30, BAKAY, BETÜL, DEVECİ, ERDEM, ZİHNİ, DEMET, DURSUN, ALİ EMRE, ÖZTÜRK, AHMET, KIRPINAR, İSMET, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET
Does psychotherapy improve alexithymia? A comparison study among patients with mild or moderate depression
2019-11-01, YILMAZ, ONUR, Mircik, Ali Barlas, Kunduz, Merve, Combas, Muge, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET, YILMAZ, ONUR, MIRÇIK, ALİ BARLAS, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET
Background: Alexithymia is reported to be a risk factor for depression. Psychotherapy is efficient for treatment of depression. Yet, the effect of psychotherapies on alexithymia is poorly understood. Objectives: We aimed to compare Cognitive Behavioral Therapy (CBT), Existential Psychotherapy (ExP) and Supportive Counseling (SUP) for therapeutic efficacy and effect on alexithymia in depression. Methods: There were 22 patients for each patient group. Sessions were performed as eight consecutive weekly and following two monthly boosters. Sixty six healthy controls were added. Prior to the sessions, patients received Sociodemographic Data Form, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-1), Hamilton Depression Rating Scale (HDRS) and 20-item Toronto Alexithymia Scale (TAS-20). The control group received Sociodemographic Data Form, SCID-1 and TAS-20. Patients additionally received HDRS and TAS-20 after their weekly and booster sessions. Results: Patients- mean TAS-20 score was greater than of controls, however, it did not have a significant change throughout the study. Mean HDRS scores of ExP and CBT groups were lower than SUP group at the end. Discussion: Alexithymia did not improve with psychotherapy. The exception was effect of ExP on externally oriented thinking. Psychotherapies all improved depression. CBT and ExP were more helpful than SUP.
Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment
2019-01-01, ÖZTÜRK, AHMET, Şahan, Ebru, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET, ÖZTÜRK, AHMET, ŞAHAN, EBRU, MIRÇIK, ALİ BARLAS, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET
Objective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.
Investigation of facial emotion recognition, alexithymia, and levels of anxiety and depression in patients with somatic symptoms and related disorders
2016-04-29, ÖZTÜRK, AHMET, KILIÇ, Alperen, DEVECİ, ERDEM, KIRPINAR, İSMET, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET
Background: The concept of facial emotion recognition is well established in various neuropsychiatric disorders. Although emotional disturbances are strongly associated with somatoform disorders, there are a restricted number of studies that have investigated facial emotion recognition in somatoform disorders. Furthermore, there have been no studies that have regarded this issue using the new diagnostic criteria for somatoform disorders as somatic symptoms and related disorders (SSD). In this study, we aimed to compare the factors of facial emotion recognition between patients with SSD and age- and sex-matched healthy controls (HC) and to retest and investigate the factors of facial emotion recognition using the new criteria for SSD. Patients and methods: After applying the inclusion and exclusion criteria, 54 patients who were diagnosed with SSD according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria and 46 age- and sex-matched HC were selected to participate in the present study. Facial emotion recognition, alexithymia, and the status of anxiety and depression were compared between the groups. Results: Patients with SSD had significantly decreased scores of facial emotion for fear faces, disgust faces, and neutral faces compared with age- and sex-matched HC (t=-2.88, P=0.005; t=-2.86, P=0.005; and t=-2.56, P=0.009, respectively). After eliminating the effects of alexithymia and depressive and anxious states, the groups were found to be similar in terms of their responses to facial emotion and mean reaction time to facial emotions. Discussion: Although there have been limited numbers of studies that have examined the recognition of facial emotion in patients with somatoform disorders, our study is the first to investigate facial recognition in patients with SSD diagnosed according to the DSM-5 criteria. Recognition of facial emotion was found to be disturbed in patients with SSD. However, our findings suggest that disturbances in facial recognition were significantly associated with alexithymia and the status of depression and anxiety, which is consistent with the previous studies. Further studies are needed to highlight the associations between facial emotion recognition and SSD.
Neurocognition in Patients with Acne Vulgaris
2014-11-01, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET, KOYUNCU, AHMET, ENGİN, İSMAİL, MELİKOĞLU, MEHMET, YILMAZ, ENVER DEMİREL, KOÇER, EMEL, DEVECİ, ERDEM, ÖZTÜRK, AHMET, KIRPINAR, İSMET
Effects of Cognitive Behavioral Therapy, Existential Psychotherapy and Supportive Counselling on Facial Emotion Recognition Among Patients with Mild or Moderate Depression
2019-07-01, YILMAZ, ONUR, Kunduz, Merve, ÇOMBAŞ, MÜGE, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET, YILMAZ, ONUR, MIRÇIK, ALİ BARLAS, ÖZTÜRK, AHMET, DEVECİ, ERDEM, KIRPINAR, İSMET
Objective: This study compared the effects of cognitive behavioral therapy (CBT), existential psychotherapy (ExP) and supportive counseling (SUP) on facial emotion recognition among mildly and moderately depressed patients. Methods: 21 patients for CBT, and 20 each for ExP and SUP groups with 60 healthy controls were investigated. Eight consecutive weekly sessions and following two monthly boosters were performed. Prior to the sessions, all subjects received Sociodemographic Data Form, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-1), and Facial Emotion Recognition Test (FERT). Patients received Hamilton Depression Rating Scale (HDRS) and FERT at the onset and after weekly and booster sessions. Results: Patients' ability to recognize surprised and neutral emotions were lower than controls. ExP group improved recognition of almost all emotions, CBT group improved only happy emotions and SUP group did not improve any emotions. HDRS scores declined in all patient groups, ExP and CBT groups had lower scores than SUP. Conclusion: MDD patients recognized surprised and neutral emotions lower than controls. ExP improved ability to recognize almost all emotions, CBT improved only happy emotions, SUP did not improve at all. ExP, CBT and SUP all led to a reduction in MDD. ExP and CBT had comparable effects and both were more helpful than SUP.
Comparing remitted unipolar and bipolar depressive disorder according to the clinical features
2014-12-01, SOYUÇOK, ETEM, ÖZTÜRK, AHMET, AYDIN, NAZAN, KIRPINAR, İSMET, ÖZTÜRK, AHMET, KIRPINAR, İSMET
Depresyon Tedavisine Ortalama Trombosit Hacmi ve Nötrofil Lenfosit Oranı Yanıtı
2016-11-20, MIRÇIK, ALİ BARLAS, ÖZTÜRK, AHMET, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET, MIRÇIK, ALİ BARLAS, ÖZTÜRK, AHMET, DEVECİ, ERDEM, YILMAZ, ONUR, KIRPINAR, İSMET
Mirtazapinin Neden Olduğu Halüsinasyonlar Bir olgu sunumu
2015-11-29, KILIÇ, ALPEREN, ÖZTÜRK, AHMET, YILMAZ, ONUR, KIRPINAR, İSMET, ÖZTÜRK, AHMET, YILMAZ, ONUR, KIRPINAR, İSMET
Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions?
2019-01-01, DEVECİ, ERDEM, Kocacenk, Tuba, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET, DEVECİ, ERDEM, ŞAHAN, EBRU, YILMAZ, ONUR, ÖZTÜRK, AHMET, KIRPINAR, İSMET