Person:
AYDIN, SİNEM

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SİNEM
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AYDIN
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Now showing 1 - 9 of 9
  • PublicationOpen Access
    Thyroid Hormone Levels in Obese Children and Adolescents with Non-Alcoholic Fatty Liver Disease
    (2014-01-01) Torun, EMEL; Ozgen, Ilker Tolga; Gokce, Selim; Aydin, SİNEM; Cesur, YAŞAR; TORUN, EMEL; ÖZGEN, İLKER TOLGA; VEHAPOĞLU TÜRKMEN, AYSEL; AYDIN, SİNEM; CESUR, YAŞAR
    Objective: We aimed to determine the association of thyroid functions with the components of metabolic syndrome (MS) and non-alcoholic fatty liver disease (NAFLD) in pediatric obese patients. Methods: The study included 109 obese children (aged 9-15 years) and a control group of 44 healthy age and gender-matched children of normal weight. NAFLD was diagnosed by conventional ultrasound examination. We assessed the anthropometric data and serum biochemical parameters including lipid profile, alanine aminotransferase (ALT), fasting glucose and insulin levels and thyroid stimulating hormone (TSH), free thyroxine (fT4) and free triiodothyronine (fT3) levels. The homeostasis model assessment of insulin resistance (HOMA-IR) was calculated as a measure of IR. Results: The mean age and gender distributions in the groups were similar (p=0.23). The mean body mass index (BMI) z-scores of obese children with grade 2-3 NAFLD were significantly higher than those of the obese children without hepatic steatosis (p<0.001). Mean ALT, triglyceride (TG) and LDL cholesterol increased and HDL-cholesterol significantly decreased as the hepatic steatosis increased (p<0.05). HOMA-IR levels in obese subjects with grade 2-3 NAFLD were significantly higher than those in both obese children without NAFLD and grade 1 NADFL (p=0.05 and 0.001, respectively). In the obese subjects, TSH levels were increased significantly as the degree of steatosis increased (p=0.04) but fT3 and fT4 levels were not different. In correlation analysis, TSH was significantly correlated with ALT, BMI SDS and the degree of steatosis. Conclusions: Obese children demonstrate an increase in TSH levels as the degree of steatosis increased.
  • PublicationMetadata only
    Effects of 18-Month Vildagliptin Treatment on Portal Vein Pressure
    (2015-06-01) Karatoprak, CUMALİ; KILICARSLAN, Rukiye; Cakirca, MUSTAFA; Aydin, SİNEM; OZKAN, Tuba; KOCAMAN, Orhan; YOLBAS, Servet; Zorlu, MEHMET; Kiskac, MUHARREM; CIKRIKCIOGLU, Mehmet Ali; KOCAKOC, Ercan; ERKOC, Reha; KARATOPRAK, CUMALİ; ÇAKIRCA, MUSTAFA; AYDIN, SİNEM; ZORLU, MEHMET; KISKAÇ, MUHARREM
  • PublicationMetadata only
    Neuroimaging Features of Acquired Metabolic and Toxic Encephalopathies
    (2018-01-01) EDIZ, Suna Sahin; Kurtcan, SERPİL; Alkan, ALPAY; Aydin, SİNEM; Tüzün, Umit; Toprak, HÜSEYİN; Aralasmak, AYŞE; KURTCAN, SERPİL; ALKAN, ALPAY; AYDIN, SİNEM; TOPRAK, HÜSEYİN; ARALAŞMAK, AYŞE
    Background: Toxic and metabolic encephalopathies are easily misinterpreted or overlooked in daily neuroimaging practices.
  • PublicationMetadata only
    Imaging Spectrum of Breast Papillary Lesions: With Special Emphasis on Atypical Appearances
    (2016-01-01) Toprak, HÜSEYİN; Yildiz, Seyma; Aralasmak, AYŞE; Aydin, SİNEM; Bilgin, Sennur; TOPRAK, HÜSEYİN; YILDIZ, ŞEYMA; ARALAŞMAK, AYŞE; AYDIN, SİNEM
    Papillary breast tumors are rare breast tumors. Presentation of papillary breast lesions varies clinically and radiologically. Standard diagnostic work-up for papillary breast lesions includes various radiological modalities such as mammography, galactography, ultrasound and MRI. Papillary lesions often have a wide spectrum of appearance on different radiological modalities, so that optimal differentiation of papillary lesions is not easy with various imaging methods. The purpose of this review article is to describe the different imaging appearances of benign and malignant papillary lesions of the breast with special emphasis on atypical appearances.
  • PublicationOpen Access
    Vildagliptin Treatment on the Portal Venous Pressure and Hepatosteatosis in Patients with Type 2 Diabetes Mellitus
    (2018-01-01) Kilicarslan, Rukiye; Cakirca, MUSTAFA; Aydin, SİNEM; OZKAN, Tuba; KOCAMAN, Orhan; Yolbas, Servet; Zorlu, MEHMET; Karatoprak, CUMALİ; Kiskac, MUHARREM; CIKRIKCIOGLU, Mehmet Ali; ERKOC, Reha; KARATOPRAK, CUMALİ; ÇAKIRCA, MUSTAFA; AYDIN, SİNEM; ZORLU, MEHMET; KISKAÇ, MUHARREM
    Objective: This study investigated how vildagliptin (a di-peptidyl peptidase 4 inhibitor) affects portal vein pressure and hepatosteatosis in patients with type 2 diabetes mellitus.
  • PublicationOpen Access
    The effectiveness of Power Doppler vocal fremitus imaging in the diagnosis of breast hamartoma
    (2014-09-01) Yildiz, Seyma; BAKAN, Ayse Ahsen; Aydin, SİNEM; Kadioglu, HÜSEYİN; SERTER, Asli; Bilgin, Sennur; Alkan, ALPAY; YILDIZ, ŞEYMA; AYDIN, SİNEM; KADIOĞLU, HÜSEYİN; ALKAN, ALPAY
    Objectives: To evaluate the usefulness of power Doppler vocal fremitus (PDVF) breast sonography for differentiation of hamartomas from other breast (malign or benign) masses. Material and methods: Two hundred and six breast masses in 180 women were evaluated. The breast lesions were scanned first by mammography (MG), then by ultrasonography (US) with PDVF imaging. Finally, biopsy was performed on lesions suspicious for malignancy (n=172). We used PDVF imaging to evaluate whether the Power acoustic Doppler artifact existed in all breast lesions. Results: Pathology results of 172 biopsied lesions showed that 83 were malign and 89 masses were benign. Totally 39 breast hamartomas were diagnosed radiologically (n=25) or histopathologically (n=14). All hamartomas (n=39) produced the power acoustic Doppler artifact as the surrounding tissue at the same depth in PDVF imaging. On the other hand, none of the malign or benign lesions, apart from hamartomas, evidenced a similar vibrational artifact as the surrounding tissue at the same depth in the PDVF imaging. Conclusion: PDVF imaging during breast sonography is an invaluable technique in the identification of breast hamartomas from other benign or malign breast masses.
  • PublicationMetadata only
    Relationship between the corpus callosum and neurocognitive disabilities in children with NF-1: diffusion tensor imaging features
    (2016-11-01) Aydin, SİNEM; Kurtcan, SERPİL; Alkan, ALPAY; GULER, Serhat; FILIZ, Mekiya; YILMAZ, TEMEL FATİH; SAHIN, Turkan Uygur; Aralasmak, AYŞE; AYDIN, SİNEM; KURTCAN, SERPİL; ALKAN, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE
    Purpose: Mild neurocognitive disabilities are commonly observed in children with neurofibromatosis type 1 (NF-1). Enlargement of the corpus callosum (CC) is one of the findings in NF-1, but the pathogenesis has not yet been clarified. In this study, we investigated whether diffusion tensor imaging (DTI) features of CC differed between children with NF-1 and healthy control subjects, and we tried to evahlate the association between the microstructural integrity of CC and neurocognitive disabilities, based on apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values.
  • PublicationMetadata only
    A case of HELLP syndrome complicated with acute pancreatitis Akut Pankreatit ile Komplike HELPP Sendromu
    (2016-05-13) BAKAR, RABİA ZEHRA; AYDIN, SERDAR; Aydin, SİNEM; ARIOGLU AYDIN, Çaǧri; BATMAZ, Gonca; BAKAR, RABIA ZEHRA; AYDIN, SERDAR; AYDIN, SİNEM
  • PublicationOpen Access
    The association of breast arterial calcification and metabolic syndrome
    (2014-01-01) Yildiz, Seyma; Toprak, HÜSEYİN; Aydin, SİNEM; Bilgin, MEHMET; Oktay, Veysel; Abaci, Okay; Kocas, Cuneyt; YILDIZ, ŞEYMA; TOPRAK, HÜSEYİN; AYDIN, SİNEM; BİLGİN, MEHMET
    OBJECTIVES: We investigated the relationship between metabolic syndrome and breast arterial calcification detected via mammography in a cohort of postmenopausal subjects. METHODS: Among 837 patients referred to our radiology department for mammographic screening, 310 postmenopausal females (105 patients with and 205 patients without breast arterial calcification) aged 40 to 73 (mean 55.9¡8.4) years were included in this study. The groups were compared with respect to clinical characteristics and metabolic syndrome criteria. Univariate and multivariate analyses identified the factors related to breast arterial calcification. RESULTS: Age, postmenopausal duration and the frequencies of diabetes mellitus, hypertension and metabolic syndrome were significantly higher in the subjects with breast arterial calcification than in those without (p,0.05). Multivariate analysis indicated that age (OR = 1.3, 95% CI = 1.1–1.6, p = 0.001) and metabolic syndrome (OR = 4.0, 95% CI = 1.5210.4, p = 0.005) were independent predictors of breast arterial calcification detected via mammography. The independent predictors among the features of metabolic syndrome were low levels of high-density lipoproteins (OR = 8.1, 95% CI = 1.0264.0, p = 0.047) and high blood pressure (OR = 8.7, 95% CI = 1.5249.7, p = 0.014). CONCLUSIONS: The likelihood of mammographic detection of breast arterial calcification increases with age and in the presence of hypertension or metabolic syndrome. For patients undergoing screening mammography who present with breast arterial calcification, the possibility of metabolic syndrome should be considered. These patients should be informed of their cardiovascular risk factors and counseled on appropriate lifestyle changes.