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SOYSAL, PINAR

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PINAR
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Subject: Erectile dysfunction ×

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Now showing 1 - 3 of 3
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    PublicationOpen Access
    Social environmental impact of COVID-19 and erectile dysfunction: an explorative review.
    (2021-09-24T00:00:00Z) Pizzol, D; Shin, J I; Trott, M; Ilie, P-C; Ippoliti, S; Carrie, A M; Ghayda, R A; Lozano, J M O; Muyor, J M; Butler, L; McDermott, D T; Barnett, Y; Markovic, L; Grabovac, Igor; Koyanagi, A; Soysal, PINAR; Tully, M A; Veronese, N; Smith, L; SOYSAL, PINAR
    Background: To date, no attempt has been made to collate literature on the relationship between the social environmental impact of COVID-19 and erectile dysfunction. The aim of this explorative review was to assess and compare the prevalence of erectile dysfunction (ED) in male healthcare workers and males during the COVID-19 pandemic. Methods: A systematic review of major databases from inception to February 2021 was conducted. Prevalence data were extracted, and a random-effects meta-analysis was undertaken. Outcomes: The pooled prevalence of ED amongst healthcare workers working in COVID-19 specific environments, and non-healthcare during the COVID-19 pandemic. Results: Of 52 initial studies, six were included for the final analysis. The pooled prevalence of ED in healthcare workers working in a COVID-19 environment was 63.6% (95% CI 20.3-92.3%), and in non-healthcare workers during the COVID-19 pandemic was 31.9% (95% CI 19.5-47.6%). Conclusion: The prevalence of ED in healthcare workers working in COVID-19 environments was higher than representative samples and is of concern. Sexual health (and by extension, overall health), should be a priority when considering ways to care for this population. Considering the social environmental impact of COVID-19 on sexual health and in particular on ED, it is important to provide adequate psychological support systems and to promote quality of life with particular attention to sexual health.
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    PublicationOpen Access
    Prevalence of erectile dysfunction in patients with chronic kidney disease: a systematic review and meta-analysis.
    (2020-05-01T00:00:00Z) Pizzol, D; Xiao, T; Yang, L; Demurtas, J; McDermott, D; Garolla, A; Nardelotto, A; Grabovac, I; Kazancioglu, Rümeyza; Veronese, N; Smith, L; SOYSAL, PINAR; KAZANCIOĞLU, RÜMEYZA
    Growing evidence reports that chronic kidney diseases (CKD) might play a role in erectile dysfunction (ED), but limited knowledge is available. Therefore, we performed a systematic review up to 21/08/2019 to investigate the associations between CKD and ED. The main analysis reported the prevalence of ED as absolute estimates (in %) with their 95% confidence intervals (CIs) and across CKD stages (when specified), hemodialysis and transplant, calculating the p for interaction across strata. Among 291 studies, we included 34 articles with 5986 men. We found an overall prevalence of 76% (95%CI: 72-79) with a high degree of heterogeneity (I2 = 84.2%; p < 0.0001). Analyzing the data by CKD stage, we found a significant higher prevalence of ED in CKD (78%; 95%CI: 75-81%; I2 = not possible) compared with hemodialysis stage (prevalence = 77%; 95%CI: 73-80%; I2 = 84.5) or to patients undergoing transplant (prevalence = 64%; 95%CI: 54-74%; I2 = 54%) (p across strata = 0.036). Considering the high prevalence of ED in men with CKD, health care practitioners should focus on issues of sexual health in men with CKD. Given the advancements in dialysis and therapy and the associated advancements in survival and life expectancy, maintaining the patients' sexual function is important for their well-being and quality of life.
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    PublicationOpen Access
    Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis.
    (2019-11-01) Soysal, PINAR; Pizzol, D; Demurtas, J; Stubbs, B; Mason, C; Isik, AT; Smith, L; Veronese, N; SOYSAL, PINAR
    Globally, there is increasing usage and legalization of cannabis. In addition to its reported therapeutic effects, cannabis has several health risks which are not clearly defined. Erectile dysfunction (ED) is the most common male sexual disorder and there are plausible mechanisms linking cannabis use to ED. No attempt has been made to collate the literature on this topic. The aim of this review was to summarize the prevalence and risk of ED in cannabis users compared to controls. A systematic review of major databases from inception to January 1, 2019, without language restriction, was undertaken to identify studies investigating cannabis use and presence of ED. The analysis compared the prevalence of ED in cannabis users versus controls. Consequently, the odds ratio (OR) with 95% confidence intervals (CI) was calculated, applying a random-effect model. Five case–control studies were included with data from 3,395 healthy men, 1,035 using cannabis (smoking) and 2,360 nonusers. The overall prevalence of ED in cannabis users was 69.1% (95% CI: 38.0–89.1), whilst the correspondent figure in controls was 34.7% (95% CI: 20.3–52.7). The OR of ED in cannabis users was almost four times that of controls (OR = 3.83; 95% CI: 1.30–11.28; p = .02), even if characterized by high heterogeneity (I2 = 90%) and the prediction intervals overlapped 1.00 (95% CI: 0.35–7.26). Data suggest that ED is twice as high in cannabis users compared to controls. Future longitudinal research is needed to confirm/refute this and explore if a dose–response relationship between cannabis and ED may be evident.