Person: SOYSAL, PINAR
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Publication Metadata only Decreased Basal Metabolic Rate Can Be an Objective Marker for Sarcopenia and Frailty in Older Males.(2019-01-01) Soysal, PINAR; Ates, Bulut; YAVUZ, I; SOYSAL, PINARPublication Metadata only Malnutrition in older age(2019-11-01T00:00:00Z) Kalan, Ugur; Arik, Ferhat; Soysal, Pınar; SOYSAL, PINARPublication Metadata only The association between physical activity and urinary incontinence among adults residing in Spain(2023-02-01) Smith L.; Soysal P.; Sánchez G. L.; Isik A. T.; Veronese N.; Demurtas J.; Ilie P.; Koyanagi A.; Jacob L.; SOYSAL, PINARPublication Metadata only Ethnic Differences in Magnesium Intake in US Older Adults: Findings from NHANES 2005-2016(2018-12-01) Jackson S. E.; Smith L.; Grabovac I.; Haider S.; Demurtas J.; Lopez-Sanchez G. F.; SOYSAL P.; Redsell S.; IŞIK A. T.; Yang L.; SOYSAL, PINARMagnesium plays a crucial role in hundreds of bodily processes relevant to aging, but consumption of dietary magnesium intake has been shown to be inadequate in a large proportion of older adults. Identifying groups at risk of low magnesium intake is important for informing targeted advice. Using data from the National Health and Nutrition Examination Survey (NHANES) 2005-2016, we examined the association between ethnicity (Caucasian/African American/Hispanic/other) and magnesium intake in a large representative sample of U.S. older adults (65 y, n = 5682, mean (SD) 72.9 (0.10) y). Analyses adjusted for total energy intake and a range of relevant covariates. Overall, 83.3% of participants were not meeting the recommended level of dietary magnesium intake, ranging from 78.1% of other ethnic groups to 90.6% of African Americans. In the fully adjusted model, magnesium intake was lower among African American older adults (-13.0 mg/d, 95% CI: -18.8 to -7.2), and higher among Hispanics (14.0 mg/d, 95% CI: 7.5 to 20.5) and those from other ethnic groups (17.2, 95% CI: 3.8 to 30.5) compared with Caucasian older adults. These results highlight the need for targeted interventions to increase magnesium intake in U.S. older adults, with a focus on African Americans, in order to reduce the burden of morbidity and ethnic inequalities in health in later life.Publication Metadata only Telomere length and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies.(2019-05-01) SMITH, L; LOPEZ-SANCHEZ, GF; FIRTH, J; KOYANAGI, A; ROBERTS, J; WILLEIT, P; WALDHOER, T; LOOSEMORE, M; ABBS, AD; JOHNSTONE, J; YANG, L; VERONESE, N; Soysal, PINAR; LUCHINI, C; DEMURTAS, J; STUBBS, B; HAMER, M; NOTTEGAR, A; LAWLOR, RT; SOYSAL, PINARPublication Metadata only Inflammation, Frailty and Cardiovascular Disease(2020-01-01T00:00:00Z) SOYSAL, PINAR; Arik, Ferhat; Smith, Lee; Jackson, Sarah E.; IŞIK, AHMET TURAN; SOYSAL, PINARChronic inflammation, which is called -inflamm-aging-, is characterized by an increased level of inflammatory cytokines in response to physiological and environmental stressors, and causes the immune system to function consistently at a low level, even though it is not effective. Possible causes of inflammaging include genetic susceptibility, visceral obesity, changes in gut microbiota and permeability, chronic infections and cellular senescence. Inflammation has a role in the development of many age-related diseases, such as frailty. Low grade chronic inflammation can also increase the risk of atherosclerosis and insulin resistance which are the leading mechanisms in the development of cardiovascular diseases (CVD). As it is well known that the risk of CVD is higher in older people with frailty and the risk of frailty is higher in patients with CVD, there may be relationship between inflammation and the development of CVD and frailty. Therefore, this important issue will be discussed in this chapter.Publication Metadata only Which Cholinesterase Inhibitor is the Safest for the Heart in Elderly Patients With Alzheimer-s Disease?(2012-05-01T00:00:00Z) ISIK, Ahmet Turan; BOZOGLU, Ergun; YAY, Adnan; Soysal, PINAR; ATESKAN, Umit; SOYSAL, PINARObjective: Cholinesterase inhibitors (ChEIs) are widely used for the treatment of Alzheimer-s disease (AD); however, their cholinergic side effects on the cardiovascular system are still unclear. In this study, we aimed to examine the side effects caused by donepezil, rivastigmine, and galantamine on cardiac rhythm and postural blood pressure changes in elderly patients with AD. Methods: Of 204 consecutive elderly patients who were newly diagnosed with AD, 162 were enrolled and underwent comprehensive geriatric assessments. The electrocardiographs (ECGs) and blood pressures were recorded at the baseline and 4 weeks after the dose of 10 mg/d of donepezil, 10 cm2/d of rivastigmine, and 24 mg/d of galantamine. Results: There were no changes relative to the baseline in any of the ECG parameters or arterial blood pressure with any of the administered ChEIs. Conclusion: It was demonstrated that none of the 3 ChEIs were associated with increased negative chronotropic, arrhythmogenic, and hypotensive effects for the elderly patients with AD.Publication Metadata only Investigation of optimum hemoglobin levels in older patients with chronic kidney disease.(2022-09-22T00:00:00Z) Kara, O; Soysal, P; Kiskac, M; Smith, L; Karışmaz, A; Kazancioglu, Rümeyza; SOYSAL, PINAR; KAZANCIOĞLU, RÜMEYZAPublication Metadata only Physical multimorbidity and incident urinary incontinence among community-dwelling adults aged ≥50 years: findings from a prospective analysis of the Irish Longitudinal Study on Ageing.(2021-07-17T00:00:00Z) Smith, Lee; Shin, Jae Il; Ghayda, Ramy Abou; Hijaz, Adonis; Sheyn, David; Pope, Rachel; Hong, Sun Hwi; Kim, Sung Eun; Ilie, Petre Cristian; Carrie, Anne Marie; Ippoliti, Simona; Soysal, PINAR; Barnett, Yvonne; Pizzol, Damiano; Koyanagi, Ai; SOYSAL, PINARPublication Metadata only Prevalence of depressive symptoms in elderly cancer patients receiving chemotherapy and influencing factors.(2018-09-01T00:00:00Z) ATAG, E; MUTLAY, F; Soysal, PINAR; SEMIZ, HS; KAZAZ, SN; KESER, M; ELLIDOKUZ, H; KARAOGLU, A; SOYSAL, PINAR