Person:
MALYA, FATMA ÜMİT

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Kurumdan Ayrılmıştır
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FATMA ÜMİT
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MALYA
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Now showing 1 - 10 of 23
  • PublicationOpen Access
    A rare tumor in a patient with hepatic hydatic cyst: adrenal hepatoid adenocarcinoma.
    (2014-01-01T00:00:00Z) Malya, FATMA ÜMİT; BOZKURT, SÜLEYMAN; HASBAHCECI, M; CIPE, G; AHMAD, IC; GÜCIN, ZÜHAL; KARATEPE, O; MUSLUMANOGLU, M; MALYA, FATMA ÜMİT; BOZKURT, SÜLEYMAN; GÜCİN, ZÜHAL
  • PublicationMetadata only
    Clinical Significance of Intraoperative Frozen Section Analysis of Pancreatic Cancer Surgical Margin at the Time of Pancreaticoduodenectomy.
    (2015-09-01) BENDER, O; BOZKURT, SÜLEYMAN; BUYUKPINARBASILI, NUR; Malya, FATMA ÜMİT; BATTAL, M; KARATEPE, O; BOZKURT, SÜLEYMAN; BÜYÜKPINARBAŞILI, NUR; MALYA, FATMA ÜMİT
  • PublicationOpen Access
    Jejunogastric intussusception: a rare complication of gastric surgery.
    (2013-01-01) CIPE, G; Malya, FATMA ÜMİT; HASBAHCECI, M; ERSOY, YELİZ EMİNE; KARATEPE, O; MUSLUMANOGLU, M; MALYA, FATMA ÜMİT; ERSOY, YELIZ EMINE
    Jejunogastric intussusception is a rare complication of gastric surgery. It usually presents with severe epigastric pain, vomiting, and hematemesis. A history of gastric surgery can help in making an accurate and early diagnosis which calls forth an urgent surgical intervention. Only reduction or resection with revision of the previously performed anastomosis is the choice which is decided according to the operative findings. We present a case of JGI in a patient with a history of Billroth II operation diagnosed by computed tomography. At emergent laparotomy, an efferent loop type JGI was found. Due to necrosis, resection of the intussuscepted bowel with Roux-en-Y anastomosis was performed. Postoperative recovery was uneventful.
  • PublicationOpen Access
    Co-existence of acute appendicitis and inflammatory myofibroblastic tumor of the small intestine: A case report
    (2015-09-01) Unver, NURCAN; Coban, GANİME; ONARAN, Oyku Izel; ARSLAN, ADNAN; Malya, FATMA ÜMİT; HASBAHCECI, Mustafa; ÜNVER, NURCAN; ÇOBAN, GANİME; KUNDUZ, ENVER; ARSLAN, ADNAN; MALYA, FATMA ÜMİT
    Introduction: Inflammatory myofibroblastic tumor as a rare neoplastic lesion is seen most commonly in the pulmonary system. Beside the presence of limited number of inflammatory myofibroblastic tumors of the gastrointestinal tract in the literature, co-existence with acute appendicitis has not been reported before. Presentation of case: A 27-year-old woman admitted to emergency department with acute abdominal pain at the right lower quadrant. The initial diagnosis was as acute appendicitis. Intraoperatively, a mass with a diameter of almost 5 cm originated from the distal ileal segments neighboring the appendix was seen. The patient was managed by segmental resection of the small intestine including the mass with appendectomy. Histologically, there were bundles of spindle cells accompanied by lymphoplasmocytic infiltration. The immunohistochemical studies showed that tumor cells were positive for smooth muscle actin, vimentin, perinuclear activity for anaplastic lymphoma kinase and CD 68. The final pathologic diagnosis was inflammatory myofibroblastic tumor. Discussion: Concomitant resection of tumoral lesions detected in the neighbor intestinal segments during appendectomy should be considered to diagnose and treat. For the diagnosis of inflammatory myofibroblastic tumor, immunohistochemistry pattern including positivity for actin, vimentin, CD 68 and anaplastic lymphoma kinase plays a crucial role. Therefore, detailed immunohistochemistry analysis should be performed in suspicious cases. Conclusion: Coexistence of inflammatory myofibroblastic tumor located in the gastrointestinal system with acute appendicitis is a rare event. Complete surgical excision should be regarded as the mainstay of the treatment. Long-term follow up with serial imaging techniques is recommended.
  • PublicationMetadata only
    Effect of pre-operative red blood cell distribution on cancer stage and morbidity rate in patients with pancreatic cancer.
    (2014-09-15T00:00:00Z) ŞENTÜRK, H; YILMAZ, A; Malya, FATMA ÜMİT; OZTURK, G; CITGEZ, B; OZDENKAYA, Y; ERSAVAS, C; AGAN, A; KARATEPE, O; MALYA, FATMA ÜMİT; ŞENTÜRK, HAKAN
  • PublicationOpen Access
    The correlation between breast cancer and urinary iodine excretion levels
    (2018-02-01) Malya, FATMA ÜMİT; Kadioglu, HÜSEYİN; Hasbahçeci, Mustafa; Dolay, KEMAL; Guzel, MEHMET; Ersoy, YELİZ EMİNE; MALYA, FATMA ÜMİT; KADIOĞLU, HÜSEYİN; DOLAY, KEMAL; GÜZEL, MEHMET; ERSOY, YELIZ EMINE
    Objective To compare urinary iodine excretion levels in patients with breast cancer and control subjects. Methods In this prospective pilot study, patients with breast cancer and normal controls were recruited. Age and menopausal status were recorded. Levels of serum thyroid-stimulating hormone, blood urea nitrogen and creatinine and urine iodine concentration (UIC) were measured. UIC levels were divided into three categories: low (<100 µg/l), normal (100-200 µg/l) or high (>200 µg/l). Results A total of 24 patients with breast cancer and 48 controls were included in the study. There were no statistically significant differences between the two groups with regard to thyroid-stimulating hormone, blood urea nitrogen or creatinine levels. When considered overall, there was no statistical difference in UIC between patients and controls. However, comparisons within each category (low, normal or high UIC) showed a significantly higher percentage of patients with breast cancer had a high UIC compared with controls. Conclusions A high UIC was seen in a significantly higher percentage of patients with breast cancer than controls. UIC may have a role as a marker for breast cancer screening. Further studies evaluating UIC and iodine utilization in patients with breast cancer are warranted.
  • PublicationOpen Access
    Comparison of Weight Loss, Ghrelin, and Leptin Hormones After Ligation of Left Gastric Artery and Sleeve Gastrectomy in a Rat Model.
    (2017-03-24) YARDIMCI, ERKAN; BOZKURT, SÜLEYMAN; CENGIZ, MB; Malya, FATMA ÜMİT; YARDIMCI, ERKAN; BOZKURT, SÜLEYMAN; MALYA, FATMA ÜMİT
    BACKGROUND Ligation of the left gastric artery (LLGA), which supplies the fundus of the stomach, may reduce the appetite hormone ghrelin, resulting in weight control. The aim of this study was to compare LLGA and sleeve gastrectomy (SG) in terms of postoperative outcomes in a rat model. MATERIAL AND METHODS Fifteen male Wistar albino rats, weighing >350 grams (range 350-525 grams), were enrolled in LLGA (N=5), SG (N=5), and control (N=5) groups. Blood samples were drawn preoperatively and also during the first and fourth week postoperatively to assay ghrelin and leptin hormone levels. Body weight was measured in each group. RESULTS The maximum reduction in ghrelin level (41.5%) was found in the LLGA group. Considerable% total weight loss (TWL) (mean 24.1%) was observed in the SG group, and slight%TWL was noted in the control and LLGA groups (means of 0.1% and 2.1%, respectively). There was no significant difference in mean percent weight change between the LLGA and the SG groups (p=0.08). Blood sample analysis revealed no statistically significant changes in ghrelin or leptin levels between the groups (p=0.9 and p=0.3, respectively). CONCLUSIONS We present evidence that LLGA causes the same reduction in ghrelin hormone levels as SG at 4 weeks after surgery in a rat model. However, LLGA did not cause the same%TWL as SG. The mechanism of weight loss in SG is most likely due to restriction and to the effects of the procedure, rather than due to neurohormonal changes.
  • PublicationMetadata only
    A novel reconstruction method for giant incisional hernia: Hybrid laparoscopic technique.
    (2015-10-01) OZTURK, G; Malya, FATMA ÜMİT; ERSAVAS, C; OZDENKAYA, Y; BEKTASOGLU, HÜSEYİN KAZIM; CIPE, G; CITGEZ, B; KARATEPE, O; MALYA, FATMA ÜMİT; BEKTAŞOĞLU, HÜSEYİN KAZIM
  • PublicationMetadata only
    Helicobacter pylori is undetectable in intraductal papillary mucinous neoplasm
    (2016-09-01) BAYSAL, Birol; Ince, ALİ TÜZÜN; Gucin, ZÜHAL; Malya, FATMA ÜMİT; TOZLU, Mukaddes; Senturk, HAKAN; BAĞCI, PELİN; Celikel, Cigdem Ataizi; Gultepe, Bilge; OZKARA, Selvinaz; PASAOGLU, Esra; DURSUN, Nevra; OZGUVEN, Banu Yilmaz; TUNCEL, Deniz; İNCE, ALİ TÜZÜN; SÜMBÜL, BİLGE; GÜCİN, ZÜHAL; MALYA, FATMA ÜMİT; ŞENTÜRK, HAKAN
    Background: About half of the world population is infected with Helicobacter pylori (H. pylori), a bacterium associated with gastric cancer and considered to be a risk factor for pancreatic ductal adenocarcinoma. Whether the bacterium is associated with intraductal papillary mucinous neoplasm, believed to be a precursor of pancreatic ductal adenocarcinoma, is unknown. The aim of this study was to investigate the presence of H. pylori DNA in tissue sections of intraductal papillary mucinous neoplasm.
  • PublicationOpen Access
    A novel sutureless colonic anastomosis with self-gripping mesh: an experimental model.
    (2014-05-15) CIPE, G; Malya, FATMA ÜMİT; HASBAHCECI, M; ATUKEREN, P; BUYUKPINARBASILI, NUR; KARATEPE, O; MUSLUMANOGLU, M; MALYA, FATMA ÜMİT; BÜYÜKPINARBAŞILI, NUR
    Introduction: Anastomotic leakage is one of the most feared complications of colorectal surgery. High morbidity and mortality rates are related to this complication and several studies had been performed to test new techniques which are suggested to reduce leakage rates. The aim of our study was to evaluate the safety and effectiveness of a novel technique sutureless anastomosis with self-gripping mesh in an animal model by examining wound healing process in anastomosis. Methods: In this study sixteen Norwegian Wistar Albino female rats were used. The rats' weights ranged from 250 to 300 g. The rats were divided into control and study groups. The control group underwent a colocolic anastomosis using the conventional method of hand-sewing with single-layer interrupted nonabsorbable sutures. The study group underwent a colocolic anastomosis using self-gripping mesh without sutures. These rats were sacrificed on the 10th postoperative day. The sample pieces obtained from the groups were subjected to anastomotic bursting pressure tests, to a test for hydroxyproline levels in the tissue and to histopathological examinations. The tissue was evaluated in terms of quantity of inflammatory cells, fibroblasts, neovascularization level and collagen content and classified according to the Ehrlich-Hunt model. Statistical analysis was done by using Mann-Whitney U test. Results: The burst pressure mean ± range of control and study groups were 162 ± 78 and 123 ± 35, respectively (P = 0.049). The mean peritoneal adhesion grades were 3.2 ± 0.7 in the study group and 2.3 ± 0.7 in the control group (P = 0.036). The operative time was significantly shorter in the study group. The difference between the groups by mean of hydroxyproline levels was found to be significant (P = 0.001). According to histopathological examinations by means of the Ehrlich-Hunt model, the fibroblast activation and collagen fiber ratio were higher in the study group and the difference between these measurements was statistically significant (P = 0.006; P = 0.028). Conclusion: This study showed that use of self-gripping meshes for colocolic anastomosis in rats is a safe and feasible method. It is suggested that the most important advantage of this technique is the shorter operative time.